2016 MADC Pilot Project Program

The MADC has extended the pilot project program submission from 12/16/2016 to 01/06/2017

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All Applicants can apply through this Application Portal

  • Internal Submission Deadline: Friday, January 6, 2017
  • Award Cycle: 2017
  • Discipline/Subject Area: Neurology
  • Funding Available: 35,000.00
  • Description:

As we seek to understand and cure Alzheimer’ disease (AD) and related dementias, the University of Michigan Alzheimer’s Disease Center (MADC) considers it among our highest priorities to support innovative, high impact research. The MADC Pilot Project Program is partially supported by the Alzheimer’s Disease Core Center (ADCC) linking the University of Michigan, Michigan State University and Wayne State University. The ADCC’s central theme focuses on identifying, understanding and modulating the numerous non-β-amyloid factors that contribute to brain dysfunction and neurodegeneration. The MADC Pilot Project Program provides “kick-starter” funds to University of Michigan (UM), Michigan State University (MSU), Wayne State University (WSU), and Veteran Affairs Ann Arbor Health System (VAAAHS) investigators to test new ideas about the causes and treatment of dementing disorders. Pilot projects should emphasize one or more of the following:

    • Center’s thematic focus on non-beta amyloid factors contributing to neuronal dysfunction and degeneration in dementia
    • Leveraging of resources available at the MADC and its Cores and co-enrollment of participants in the MADC’s longitudinal cohort
    • Utilization of databases available at the MADC, the Michigan Brain Bank via the MADC Neuropathology Core, the National Alzheimer’s Coordinating Center (NACC), or the Alzheimer’s Diseases Neuroimaging Initiative (ADNI)
    • Novel methods of detecting/treating cognitive changes
    • Emphasis on studying cognition and unique challenges to diagnosing and treating age-related dementia in underrepresented minorities
    • Focus on aging, frailty and cognitive changes due to aging in older adults

The MADC is committed to funding two pilot projects this year, open to any investigator at the three Universities (UM, MSU & WSU). The MADC invites members of the scientific community from these partner institutions to submit applications for pilot project funding. The proposed research must be relevant to Alzheimer’s disease and/or non-amyloid related dementias. We anticipate funding at least two $35,000 (direct cost only) projects for a period of one year, beginning 02/1/17 and ending 01/31/18.

We encourage UM/MSU/WSU investigators at all levels to apply. Applications received from junior investigators, established investigators new to Alzheimer’s disease or dementia research, and investigators who have not previously received pilot project funding through the MADC, will be looked upon most favorably. Emphasis will also be given to projects that link researchers from multidisciplinary fields and across the Universities. Applications should be no more than three pages in length, and describe research commensurate with a one year award. Reviewers will rank proposals based on their potential significance and impact, investigator and investigative team, research plan, likelihood of leading to future NIH or private foundation funding, relevance to AD and related dementias, and relevance to the MADC’s thematic focus on non-amyloid factors. Applications are due by Friday, Jaunary 6, 2017.

Successful applicants will be required to provide a six month progress report and a final end-of-year report and presentation to the MADC Executive Committee. At the end of the funding period or soon thereafter, the MADC is looking to see one or more publications as a result of the pilot project, and/or continued funding in the form of a new R01 or equivalent grant.

The award can be used for the direct support of salary and/or supplies (no indirect support is allowed). No tuition support is available. Equipment in excess of $5000 needs special justification and is generally not encouraged.

Submission: Applications should be submitted through the University of Michigan Medical School Office of Research Competition Space portal: https://umms.infoready4.com/#homePage

Three page proposals that include a specific aims section are due by Friday, Jaunary 6, 2017. Budget and budget justification, biosketch in NIH format, and other support documents are also due at this time.

Biosketch, budget/budget justification, and other support templates are provided in the Competition Space. Start date is expected to be February 1, 2017, but is somewhat flexible.

Note: Any project involving animal or human samples must provide proof of IACUC or IRB approval prior to initiation of the project. If this is not obtained within 60 days of the funding date for the project, funding will be withdrawn.

For questions please contact Arijit Bhaumik at 734-936-8281, email: arijit@umich.edu

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