July 12, 2016

About Us

  • Established at Michigan Medicine and based in the Department of Neurology, the Michigan Alzheimer’s Disease Center aims to

    • Conduct and support research on Alzheimer’s disease and related disorders;
    • Promote state-of-the-art care and wellness for individuals and families affected by memory loss;
    • Increase dementia awareness through collaborative education and outreach efforts.

    Our Center goals are guided by an Internal Advisory Board and a Community Advisory Board.  To reach our goals, we

    • Support recruitment for memory and aging research.
    • Connect interested volunteers to research opportunities.
    • Provide programs focusing on whole-body health and well-being through our Wellness Initiative.
    • Collaborate with three local chapters of the Alzheimer’s Association to enhance our community outreach through education programs.

    Please view a video from Center Director, Henry Paulson, MD, PhD here.

  • A portion of the larger Center is dedicated to research, funded by the National Institutes of Health. Taking advantage of the University of Michigan’s deep infrastructure in dementia and aging research, the Michigan Alzheimer’s Disease Research Center fosters and enhances innovative research in Alzheimer’s disease and related dementias toward better understanding of, and eventual preventive treatment for, these devastating diseases. Our Center is one of 30 other National Institutes of Health-funded Alzheimer’s Disease Research Centers across the country.

    The Michigan Alzheimer’s Disease Research Center is a truly regional Alzheimer’s Disease Research Center linking three universities across the state of Michigan – University of Michigan in Ann Arbor, Wayne State University in Detroit, and Michigan State University in Lansing and Grand Rapids. The regional presence of our Alzheimer’s Disease Research Center formally links efforts at all three major Michigan universities providing a critically important statewide resource for researchers, trainees, health care professionals and the broader public.

    To support research efforts, our Center is structured in the following way:

    Administrative Core

    Led by Director Hank Paulson, MD, PhD, the administrative core is responsible for creating and implementing structural improvements within the center while managing staffing, financial and research related resources. This core helps to sustain the wide range of research studies and programs supported by the Center.

    Clinical Core

    The clinical core, led by Benjamin Hampstead, PhD, Judy Heidebrink, MD, and Bruno Giordani, PhD, oversees the wide range of research studies supported by the Center and creates new opportunities for innovative and cutting edge research. A full list of supported research can be found under the Research tab. The clinical core works with the data management and statistical core and the outreach and recruitment core to develop materials for research dissemination into everyday patient care.

    Data Management and Statistical Core

    The data management and statistical core, led by Hiroko Dodge, PhD, and Ivo Dinov, PhD, helps maintain the academic and research productivity of the Center by integrating data and helping to disseminate data to supported research investigators. This core focuses on predictive Big Data analytics, taking advantage of the unique investigators and infrastructures available at the University of Michigan.

    Neuropathology Core

    The neuropathology core helps to maintain the University of Michigan Brain Bank and the Protein Folding Diseases Initiative. Resources from the neuropathology core foster studies of the underlying proteinopathies of dementias with the goal of translating discoveries into new therapeutic strategies. Andrew Leiberman, MD, PhD serves as core leader of the neuropathology core, with Scott Counts, PhD, as the Michigan State University liaison for building Brain Bank resources in western Michigan.

    Outreach and Recruitment Core 

    The outreach and recruitment core leads education and outreach efforts in order to promote community participation in Center research and educational activities. This core, led by Scott Roberts, PhD, helps to maintain successful relationships with community partners across the state.

    Research Education Component Core

    Led by Roger Albin, MD, and Co-led by Peter Lichtenberg, PhD, ABPP, the research education component core is dedicated to training and mentoring junior investigators. This core hopes to foster career development in interdisciplinary dementia research and has developed a curriculum to educate junior investigators on dementia and dementia research.

  • Staff

    Arijit K. Bhaumik, BA, CCRP - Research Administrator

    Arijit Bhaumik, BA, CCRP - Research Administrator 

    Contact: arijit@med.umich.edu or 734-936-8281

    Arijit has worked at the Michigan Alzheimer’s Disease Center since 2007, managing neurodegenerative clinical trials and longitudinal research projects. He has been the Center's Research Administrator since 2016. Ari's expertise lies in clinical research protocol management and working with cross-generation populations. He has a deep understanding of highly intricate grants that involve multiple investigators at multiple universities, complex budgets, and multiple sub-awards. Ari possesses all of these skills and is recognized by his peers for his ability to bridge the gap between research budgeting, research operations planning and execution of the research strategy. He is an excellent communicator, emphasizing creative and dynamic strategies for multicultural, cross-generational and multipurpose understanding of research within our Center. He earned his Bachelor’s degree in Clinical Psychology and Counseling at Richmond University, London, UK, and studied Cognitive Psychology at the post-baccalaureate level at McGill University in Montreal, Quebec, Canada. He is also a Certified Clinical Research Professional (SoCRA). In 2018 he was awarded the Camille Mrozowski Award for Service and Excellence in Research sponsored by the University of Michigan Medical School Office of Research.

    Holly Bunker, MS - Memory & Aging Project Recruitment Coordinator

    Holly Bunker, MA - Memory & Aging Project Recruitment Coordinator 

    Contact: hlbunker@med.umich.edu or 734-615-5319

    Holly Bunker joined the Center in 2018 as the Memory & Aging Project Recruitment Coordinator. Holly has a BA in Psychology from Michigan State University and a master's degree in Health Education from Wayne State University. Holly is responsible for enrolling participants into the Center's primary research study, the University of Michigan Memory and Aging Project (UM-MAP), and is our research participants’ main point of contact throughout their participation in this longitudinal study. In addition to managing the UM-MAP study, Holly works closely with study coordinators for other Center-supported studies.

    Stephen Campbell, LMSW - Research Projects Manager

    Stephen Campbell, LMSW - Research Projects Manager 

    Contact: stepcamp@umich.edu or 734-763-2361

    Stephen is responsible for a variety of activities within the Clinical Core. He manages the Center's core study, the University of Michigan Memory and Aging Project (UM-MAP) which includes direction of study related activities and regulatory issues. Stephen also manages collaborative efforts between the University of Michigan and other research institutions. Stephen received Master’s and Bachelor’s degrees from Eastern Michigan University.

    Katrail Davis, BS - Research Assistant

    Katrail Davis, BS - Research Assistant 

    Contact: dkatrail@med.umich.edu

    Katrail Davis is a Wayne State University graduate, having earned a BS degree in psychology. She joined the Center in 2019 as a Research Assistant. At the Center, Katrail helps to administer neuropsychological assessments. She is currently preparing to apply to graduate schools with the goal of becoming a clinical psychologist.

    Erin Fox, BA - Communications Specialist

    Erin Fox, BA - Communications Specialist

    Contact: eefox@med.umich.edu or 734-232-2459

    Erin Fox is the Center's Communications Specialist. She is responsible for coordinating the Center's communications channels including the website, newsletters, e-newsletters, social media, flyers, presentations and more. She also markets and advertises Center activities and programs in the community and to professionals. Erin plans events for the Center including health fairs, symposiums, and fundraisers. She graduated from the University of Michigan with a BA degree in Communication Studies.

    Kimberly Foxworthy, BS - Phlebotomist & Data Assistant

    Kimberly Foxworthy, BS - Phlebotomist & Data Assistant 

    Contact: foxwortk@med.umich.edu

    Kimberly Foxworthy joined the Center in 2019. She works as both a phlebotomist in the Clinical Core and as an assistant in the Data Core. Kimberly graduated Michigan State University in 2017 with a BS degree in neuroscience. She is currently in the process of applying to medical schools and hopes to one day become a Michigan physician.

    Renee Gadwa, MBA - Outreach and Education Program Manager

    Renee Gadwa, MBA - Outreach & Education Program Manager 

    Contact: rgadwa@med.umich.edu or 734-764-5137

    Renee is responsible for the management, performance and completion of outreach and recruitment activities at the Center and in the community. She leads a wide range of educational events, including health fairs, lectures and community presentations. Renee's job also focuses on the development, implementation and evaluation of all activities and programs of the Carl Rinne Lewy Body Dementia Initiative. Renee has nearly ten years of experience in dementia care, education, and support in the long term care setting and has been at the Center since 2015. She earned her Bachelor’s degree in Health Science with a minor in Psychology from Grand Valley State University and her MBA in Healthcare Management from Southern New Hampshire University.

    Theresa Gierzynski, MSW - Research Coordinator

    Theresa Gierzynski, MSW - Research Coordinator 

    Contact: gierzyns@med.umich.edu or 734-615-0612

    Theresa Gierzynski joined the Center in 2018 as a Research Coordinator. Her role includes administering and scoring neuropsychology assessments, study coordination, and recruiting and managing research participants for a multi-phase study. Theresa has been a professional in the field of aging and dementia for nearly a decade. She has formerly worked as a Research Technician at Wayne State University’s Institute of Gerontology on several research projects and was a lead author on a peer-reviewed publication. Theresa was also employed as a Program Coordinator at the Alzheimer’s Association – Greater Michigan Chapter and provided education and outreach to healthcare professionals, family caregivers, and those living with dementia. Theresa Gierzynski earned her Bachelor’s degree in Psychology from Madonna University in 2011 and her Master of Social Work degree from Wayne State University in 2018.

    Kate Hanson, MA - Recruitment Coordinator

    Kate Hanson, MA - Recruitment Coordinator 

    Contact: katsch@med.umich.edu or 734-764-0212

    Kate Hanson joined the Center in 2018 working for the Data Core in Research Support. In 2019, Kate joined the Outreach & Recruitment Core where she recruits participants into the many studies affiliated with the Center and acts as a liaison between the Data, Outreach, and Clinical Cores. Kate earned both a BA in Psychology and an MA in Education at the University of Michigan. She lives in Ann Arbor with her son and their dog and two cats.

    Molly Hutchison, MPH Candidate - Outreach & Recruitment Intern

    Molly Hutchison, MPH Candidate - Outreach & Recruitment Intern 

    Contact: hutchme@med.umich.edu

    Molly Hutchison is an intern with the Outreach and Recruitment Core. She assists with communications and planning events for the community. She holds a Bachelor of Science from Central Michigan University in Community Health Education. Also, Molly is a graduate student at the School of Public Health within the Health Behavior and Health Education Department at the University of Michigan. Her background is in health communications, education, and event planning from working in several sectors including a health department, non-profits, and university health. She is excited to continue her passion of health communications and education within the field of Alzheimer’s and dementia.

    Marisa Kelly, BA - Research Assistant

    Marisa Kelly, BA - Research Assistant 

    Contact: bkelly@med.umich.edu or 734-936-8803

    Marisa Kelly joined the Center as a Research Assistant in 2018. Her role includes administering neuropsychological assessments and serving as IRB/Regulatory Affairs support. Marisa earned her BA degree in Psychology from Michigan State University and is currently completing her second year as a Premedical Postbaccalaureate through the University of Michigan Medical School's MEDPREP program.

    Nancy Laracey, BA - Center Administrator

    Nancy Laracey, BA - Center Administrator 

    Contact: laracey@med.umich.edu or 734-936-8764

    Nancy oversees the Center's daily operations and is responsible for administrative, financial and human resources activities. Nancy earned her BA degree from Michigan State University. She has an outstanding record of service, having dedicated over thirty years of her career to the University of Michigan in various positions in the Medical School.

    Kelly Mattingly, LMSW - Support Group Facilitator

    Kelly Mattingly, LMSW - Support Group Facilitator

    Contact: mattingke@med.umich.edu

    Kelly joined the Center in 2017 as a support group facilitator for care partners of people living with Lewy body dementia. With a background in hospice, home health, and long term care settings, Kelly has nearly ten years of experience in dementia care.  She earned her bachelor’s degree in Social Work from Western Michigan University and her masters from the Denver University School of Social Work in 2009.  Kelly currently supports the Rinne Lewy Body Dementia Initiative’s Ann Arbor, Brighton, and Southfield Lewy body dementia support groups.

    Shehroz Malik - Brain Bank Laboratory Technician

    Shehroz Malik - Brain Bank Laboratory Technician 

    Contact: samalik@med.umich.edu

    Shehroz Malik joined the Center as the Michigan Brain Bank Laboratory Technician in 2017. Shehroz plays an important role in distributing samples to Michigan Brain Bank collaborators across the University of Michigan campus and throughout the United States. He is earning a Bachelor’s degree in Cell and Molecular Biology & Biomedical Engineering from the University of Michigan with an expected graduation date in 2021. He is interested in learning about the brain anatomy and investigating the crucial factors of neurodegenerative pathology. Shehroz intends to attend medical school and one day become a neurosurgeon.

    Nicolas May, MS - Database Specialist

    Nicolas May, MS - Database Specialist 

    Contact: ldmay@med.umich.edu or 734-615-3593

    Nic joined the Michigan Alzheimer's Disease Center in 2018 as a database specialist working most closely with the Data Management and Statistical Core and the Clinical Core. When it comes to data, he does the munging, helps automate pipelines, ensures that everything the Center stores is harmonized and unified, and generally uses technology to help speed things up, answer questions, and solve problems. He earned a Master's degree in Applied Linguistics at the University of Illinois at Chicago.

    Rebecca Pantis, BS - Research Coordinator

    Rebecca Pantis, BS - Research Coordinator 

    Contact: repantis@med.umich.edu or 734-615-7421

    Rebecca joined the Center as a Research Coordinator in 2018. She works with the Clinical Core on the University of Michigan Memory and Aging Project (UM-MAP). Her role in the Clinical Core is to educate participants about the UM-MAP study, collect demographic information, and administer neuropsychological assessments. She also assists with the coordination and supervision of MRI scans and computerized testing. Rebecca graduated from the University of Michigan with her BS degree in Biopsychology, Cognition, and Neuroscience. Rebecca is interested in getting to know more about neurodegenerative diseases and hopes to continue doing more research after she attends medical school.

    Matthew Perkins, BS - Michigan Brain Bank Coordinator

    Matthew Perkins, BS - Michigan Brain bank Coordinator 

    Contact: perkmd@med.umich.edu or 734-647-7648

    For autopsy assistance: 734-936-6267 (pager #9198)

    Matthew Perkins is the coordinator of the Michigan Brain Bank. He has been involved in research at the University of Michigan since 2012. Matthew coordinates the Center's brain autopsy services and collaborates with research groups across the University of Michigan campus. He is passionate about improving clinical care and research through his involvement in autopsy services. Matthew earned his BS degree in Brain, Behavior, and Cognitive Science from the University of Michigan. For more information about the Michigan Brain Bank, visit the website here.

    Betsy Posby, NP - Nurse Practitioner

    Betsy Posby, NP

    Contact: blwar@med.umich.edu

    Betsy Posby joined the Center in 2018. Her role includes administering neurological assessments, recruiting for studies, and providing education to research participants. Betsy completed her undergraduate nursing degree at the University of Michigan. She spent six years as a research Registered Nurse at the Rush Alzheimer's Disease Center in Chicago. She spent the second half of those six years completing her Doctorate in Nursing Practice at Rush University, studying to be an Adult/Gerontology Nurse Practitioner. As a nurse practitioner, Betsy has worked in palliative care, long-term care and home health.

    Laura Rice-Oeschger, LMSW - Wellness Coordinator

    Laura Rice-Oeschger, LMSW - Wellness Coordinator 

    Contact: lerice@umich.edu or 734-936-8332

    Since 2012, Laura has led the Wellness Initiative where she designs, implements, and evaluates wellbeing and self-care programming for family caregivers. Moved by family experiences with long-term illness and memory loss, Laura has worked in dementia care for over twenty years in a variety of capacities. She was the first Director of Michigan Medicine’s Silver Club Memory Loss Programs prior to serving as the clinical manager for the Early Stage Initiative at the Los Angeles regional Alzheimer’s Association. Laura is a national and state presenter on memory loss and caregiver wellbeing, has advanced professional training in mindfulness-based interventions and holds professional certifications in aging, dementia and contemplative clinical care.  Laura is an Anthony V. DeVito II Memorial Award recipient. This award is presented annually by the U-M Geriatrics Center to recognize outstanding service, dedication and commitment to excellence in geriatrics education in Michigan. She received her MSW from the University of Michigan School of Social Work in 1997.

    Edna Rose, PhD, MSW, RN-BC - Minority Outreach Specialist

    Edna Rose,PhD, MSW, RN-BC - Minority Outreach Specialist 

    Contact: ednarose@med.umich.edu or 734-936-8329

    Since 2008, Dr. Edna Rose has provided education about the risk factors associated with dementia and the benefits of participating in research to minority communities. She has successfully enhanced minority inclusion in Center-supported studies through linkages at local churches, sororities, fraternities and other social organizations. Dr. Rose received her MSW and PhD from Clark Atlanta University in Social Work Planning and Administration, and her undergraduate nursing degree from Kennesaw University in Atlanta.

    Sarah Shair, MS - Research Coordinator

    Email: sshair@med.umich.edu

    Phone: 734-615-0612

    Sarah administers and scores the neuropsychological assessments for the Memory and Aging Project. In addition, she assists in managing the daily operations of ongoing research studies and participates in outreach and education activities. She earned her Bachelor’s degree in Psychology from the University of Michigan and her Master’s degree in Clinical Psychology from Wayne State.

    Sherry Teboe - Data Manager

    Sherry Teboe - Data Manager

    Contact: steboe@umich.edu or 734-936-0836

    Sherry has made her career at the University of Michigan for over forty years and has been a vital member of the Center for more than thirty of those years.  Sherry is involved in creating the secure data entry system. She ensures that all data collected from Center-supported studies remain confidential and ready for analysis by research investigators who are interested in enhancing our understanding of memory loss and dementia. She is very interested in spending time with the elderly to grow from their years of wisdom and their wonderful sense of humor.

    Jalyn Walker, MPH Candidate - Outreach & Recruitment Intern

    Jalyn Walker, MPH Candidate - Outreach & Recruitment Intern

    Contact: jalynw@med.umich.edu

    Jalyn Walker is currently an Outreach & Recruitment Intern. Jalyn is affiliated with the University of Michigan School of Public Health as a Masters Candidate studying Health Behavior & Health Education, with a certificate in Injury Science. She earned her Bachelor’s Degree in Sociology, with a focus in Health & Medicine, at the University of Michigan. Jalyn’s interests lie in community outreach coordination, chronic disease and illness, and preventable injuries and disease. She is able to comprehensively explain the intricacies that exist between social networks and their effect on ones health, create intervention plans for at risk communities, and expand social outreach functions and methods.

    Louann Walch, BA - Data Entry Specialist

    Louann Walch, BA - Data Entry Specialist 

    Contact: louann@med.umich.edu

    Louann has been at the University of Michigan for over ten years and became a member of the Center in 2019. She works as a Data Entry Specialist in the Data Core. She obtained her Bachelors of Business Management Healthcare in 2012 at Cleary University. She enjoys spending time with her husband, daughter, and her two dogs.

    Amber Williams, MSA - Education Program Coordinator

    Amber Williams, MSA - Education Program Coordinator

    Email: amcwi@med.umich.edu

    Amber Williams is the Center's Education Program Coordinator. She has a dual degree in Nutrition Science and Dietetics from Michigan State University as well as a specialization in Latin American and Caribbean Studies. She attained her Master of Science in Health Services Administration from Central Michigan University. She has over 10 years of experience in education, wellness, nutrition and community outreach. She has found much success in her career by promoting education, creating relationships, and building rapport with the community. Amber is the lead for Center's Detroit Advisory group. She works with clinical and outreach faculty and staff to enhance recruitment into research studies, especially recruitment from underrepresented groups. She continues to build already established connections with a particular focus on African American organizations. She is also responsible for coordinating the Center's events.

    Jonathan Reader, MS - Database Administrator Associate

    Jonathan Reader, MS - Database Administrator Associate 

    Contact: readerj@med.umich.edu or 734-936-9048

    Jonathan joined the Michigan Alzheimer's Disease Center in July 2019 as a database administrator associate. He earned his master's degree in Human Development & Family Studies from The Pennsylvania State University. He is interested in using technology to improve the efficiency of the research process as a whole. This includes working with data from collection to publication with the ultimate goal of improving individuals’ lives via policy-level impact. In his spare time, he enjoys Netflix, reading, and spending time with his friends and family (including his cat, Albany).

    Olivia Cross - Michigan Brain Bank Research Technician

    Olivia Cross - Michigan Brain Bank Research Technician 

    Contact: ocabedi@med.umich.edu or 734-647-7648

    Olivia is a research technician at the Michigan Brain Bank and a recent graduate of the University of Michigan. Olivia earned her Bachelor’s in Biopsychology, Cognition, and Neuroscience and hopes to continue her education in Biochemistry while preparing for medical school. As a Brain Bank research technician Olivia plays a critical role in tissue collection via autopsy services and distribution to researchers throughout the country. Prior to the Brain Bank Olivia’s research included use of animal models to study the role of abnormalities in the cortical cholinergic system leading to attentional deficits that characterize a variety of both neuropsychiatric and neurodegenerative disorders. Olivia is very excited to converge her research of animals to translational clinical research in humans and to further develop an understanding of the intricacies of clinico-pathologic diagnoses in neuro and psychopathology.

     

  • Faculty & Investigators

    Roger Albin, MD

    Roger AlbinAssociated with the MADC as the Research Education Component Core Leader, Dr. Albin is a Professor of Neurology at the University of Michigan. He held the title of Brain Bank Director at the University of Michigan from 1998 through January of 2016. In addition to caring for patients with cognitive disorders, he studies basic disease mechanisms and participates in human imaging studies seeking to improve our diagnosis of dementing disorders. He also performs research on brain chemical factors that influence the production of beta-amyloid, a key disease protein in Alzheimer’s disease. Dr. Albin is passionate about advancing disease knowledge so that we can treat patients better. He attended medical school at the University of Pittsburgh and received his Neurology training at the University of Michigan.

    Neil Alexander, MD, MS

    Dr. Alexander graduated from the University of Minnesota Medical School, Minneapolis and received a clinical research design and biostatistics master’s degree from University of Michigan. He completed his internal medicine residency at the University of New Mexico Affiliated Hospitals and a geriatrics fellowship at the University of Michigan. He is a past research fellow at the University of Michigan Institute of Gerontology. Dr. Alexander is board-certified in internal medicine and geriatrics. He has a special interest in exercise, mobility, falls and rehabilitation in older adults. He is the Director of the VA Ann Arbor Geriatric Research Education and Clinical Center.

    Nancy Barbas, MD, MSW

    nancy_barbas-e1364239437708Associated with the MADC for many years, Dr. Barbas is Associate Professor of Neurology and Director of the Cognitive Disorders Clinic at the University of Michigan Health System. She has been on the faculty of University of Michigan Medical School and Health System since 1991. Dr. Barbas’s clinical interests include cognitive disorders in adults, such as Alzheimer’s disease and related dementias, and general geriatric neurology. She is active in clinical trial research for treatment development for Alzheimer’s disease and other dementias. She actively trains the next generation of professionals, teaching them state-of-art dementia care techniques and research skills. She has published articles and chapters on dementia topics. Nan has spent the majority of her years in higher education in Ann Arbor, Michigan obtaining Bachelors of Arts (BA), Masters in Social Work (MSW), and Doctor of Medicine (M.D.) degrees from the University of Michigan. She continued her training at Tufts New England Medical Center in Boston completing a Neurology Residency and a Neuro-ophthalmology Fellowship.

    Sami Barmada, MD, PhD

    Dr. Barmada currently serves as Assistant Professor of Neurology at the University of Michigan. He was recruited from UCSF to the University of Michigan in 2013. Dr. Barmada divides his time between the laboratory, Cognitive Disorders Program, and the classroom. In his investigations of molecular mechanisms in FTD including TDP43 proteinopathies, Dr. Barmada employs automated microscopy. He treats patients in the Cognitive Disorders Program, with an emphasis on individuals with dementia and motor neuron disease. Dr. Barmada is also an Assistant Professor of Neurology.

    Andrea Bozoki, MD

    andreabozokiDr. Andrea Bozoki is an Associate Professor in the Department of Neurology and Department of Radiology at Michigan State University. The focus of her individual scholarship has been the exploration of cognitive function during the transition between healthy aging and early dementia. In particular, she is interested in the structure-function relationships underlying the evolution of de novo Mild Cognitive Impairment and Alzheimer’s disease, as well as understanding what factors can prevent or allay cognitive decline during aging. Her work has utilized primarily neuropsychometric testing along with functional and structural MR imaging. More recently, she has included amyloid and FDG-PET data to examine the relative advantages of using a broader multi-modal imaging approach to biomarker development.

    Charles Burant, MD, PhD

    Dr. Burant directs a research program that integrates molecular phenotyping (including metabolomics) with dietary, clinical and behavioral phenotypes to understand the development of obesity, insulin resistance and diabetes. He has a specific interest in intermediary metabolism and he has integrated metabolomics with other technologies to gain a more complete understanding of cellular metabolism. Dr. Burant directs the Michigan Regional Comprehensive Metabolomics Resource Core (U24), which is one of six NIH-funded metabolomics centers. At the MADC, he provides advice on the use of metabolomics profiling to gain insights into the pathophysiology of neurodegenerative diseases and the potential relationship to metabolic syndrome, obesity, diabetes and other metabolic states.

    David Burke, PhD

    David Burke, PhD, is a Professor of Human Genetics and a Clinical Core Consultant for the MADC. His research interests include the development of low cost, single nucleotide variant DNA and RNA testing methods which are employed by the MADC in genetic risk factor assessment. The robust methods are currently used in the laboratory to perform over ten thousand human, mouse, viral and bacterial SNP genotypes per year.

    Sandra Camelo-Piragua, MD

    Dr. Camelo-Piragua is a Clinical Assistant professor in the Neuropathology Division at the University of Michigan. She received her M.D. from the University of Antioquia in Medellin, Colombia, and did her post-doctoral research fellowship at the Center for Neurologic Disease, Brigham and Women’s Hospital, Boston, MA, where she was involved in the study of molecular signature of multiple sclerosis and analyzing the effects of histone deacetylase inhibitors on murine models of multiple sclerosis and amyotrophic lateral sclerosis. She received further training in Neuropathology at Massachusetts General Hospital, Boston, MA, from 2008-2010. In addition to her clinical and research interests, Dr. Camelo-Piragua enjoys teaching of neuroanatomy and neuropathology to medical students, residents and fellows. Dr. Camelo-Piragua is interested in developing information technology tools that help brings the teaching of neuropathology to a broader audience. Dr. Camelo-Piragua is member of American Association of Neuropathologists, European Confederation of Neuropathological Societies, United States and Canadian Academy of Pathology, the College of American Pathologists and is board certified in Anatomic and Clinical Pathology and in Neuropathology.

    Scott Counts, PhD

    scott-countsDr. Counts is an Associate Professor of Translational Science & Molecular Medicine at Michigan State University. The goal of his research is to understand the molecular pathogenic mechanisms of selective neuronal vulnerability in the preclinical and prodromal stages of Alzheimer’s disease (AD). His pre-doctoral training with Dr. Allan Levey at Emory emphasized the importance of combining carefully controlled human tissue research with cellular and molecular modeling to reveal potential pathways underlying AD progression. He is the MSU liaison for the UM ADC Neuropathology Core and Brain Bank. His duties include generating awareness and providing training to MSU investigators in the procurement and use of postmortem tissue and bio-specimens from UM for dementia research. He also serves as the MSU representative to the Brain Bank Tissue Request Committee.

    Hiroko Dodge, PhD

    hiroko4Dr. Dodge is the Milton and Carolyn Kevreson Research Professor of Neurology at the University of Michigan. She is a Fellow in the Gerontological Society of America (GSA). She serves as a statistical editor for Alzheimer’s & Dementia (the official journal of the Alzheimer’s Association) and a senior associate editor for Alzheimer’s & Dementia: Translational Research and Clinical Advancements, a sister journal of Alzheimer’s & Dementia. She also serves on the statistical editorial board for International Psychogeriatrics. Dr. Dodge joined the MADC as the Data Core Leader in 2010. She has been successfully directing two Alzheimer’s Disease Centers’ Biostatistics and Data Cores: the Michigan ADC and the NIA-funded Layton Aging ADC at Oregon Health & Science University, Portland, Oregon. These dual positions allow her to facilitate collaborations between the two centers. Dr. Dodge’s research interests are diverse and include a) distinguishing normal cognitive aging from pathological cognitive decline, b) testing whether stimulation through social interactions can improve cognitive functions, c) clinical trial methods, and d) examining lifestyle and environmental factors that lead to healthy cognitive aging. A native of Japan, she has a longitudinal cohort in Okinawa, Japan and collaborates with the Okinawa Centenarian Study group.

    For more information about Hiroko, visit her webpage here.

    Bruno Giordani, PhD

    giordaniDr. Giordani is a Chief of Psychology, and a tenured Professor in the Psychiatry, Neurology, and Psychology Departments as well as the School of Nursing. He is a University Faculty Ombuds at the University of Michigan. Associated with the MADC for over 25 years, Dr. Giordani has a longstanding history of connecting with the community to promote a better understanding of Alzheimer’s disease and related conditions. He has served on the Executive Board of the Alzheimer’s Association, Michigan Great Lakes Chapter (MGLC) since 2007 and has been both its Board Chair and National Representative, as well as a Steering Committee being a member of the national Association’s Assembly Steering Committee. His research initiatives focus on a cross-cultural perspective on the early assessment of cognitive and behavioral changes associated with medical illness and the interaction of cognition and mobility across the life-span. Dr. Giordani completed his MA and PhD in Clinical Psychology at the University of Virginia and received his postdoctoral training in Clinical and Research Neuropsychology at the University of Michigan.

    Yuangfang Guan, PhD

    yuanfang_guanDr. Guan is Assistant Professor in the Department of Computational Medicine & Bioinformatics at the University of Michigan. She received her PhD training in functional genomics at Princeton University followed by a brief postdoctoral fellowship, also at Princeton. In 2011, she joined the University of Michigan where her research as an independent investigator focused on developing generic, first-principle computational solutions to large-scale biomedical data. She has created seven best-performing algorithms in the past three years, breaking the record of DREAM’s (Dialogue of Reverse Engineering and Methods) 10 years of history. She has best-performing algorithms in areas such as population genetics, DNA variation, transcriptome data, proteomic data, medical imaging, biochemical structures, cancer, rheumatoid arthritis, and most notably, Alzheimer’s Disease and cognitive impairment.

    Mark Haacke, PhD

    markDr. Haacke is an original pioneer of MR angiographic imaging, fast imaging and cardiovascular imaging, and more recently has developed a powerful new method for imaging veins, micro-hemorrhaging and iron called Susceptibility Weighted Imaging (SWI). His research has focused on studying the role of magnetic field variations in the human body and applying the results to clinical translational research. SWI may in fact become an important biomarker not just for different forms of iron but in investigating the etiology of a number of key diseases such as aging, multiple sclerosis, stroke and trauma. More recently his work has focused on extending SWI to quantitative susceptibility mapping (QSM) as a means to map iron and oxygen saturation.

    Benjamin Hampstead, PhD, ABPP/CN

    bhampste-1

    Dr. Hampstead joined the U-M faculty in September 2014 as an Associate Professor in Psychiatry and Staff Neuropsychologist in the Ann Arbor VA Healthcare System. He is the Clinical Core Leader at the MADC. Dr. Hampstead is an expert in functional imaging and nonpharmacological approaches to enhance age-related memory function (e.g., cognitive rehabilitation and direct brain stimulation). Through his appointment in the Ann Arbor VA Healthcare System, he is well-positioned to ensure that our older veterans have access to cutting-edge research and clinical procedures.

    Judy Heidebrink, MD, MS

    judy_heidebrink-e1366663002363Dr. Heidebrink is a Richard D. and Katherine M. O’Connor Research Professor and has been affiliated with the Michigan Alzheimer’s Disease Center since 1995, when she began her fellowship training in Geriatric Neurology. She is also the Director of the Cognitive Disorders Clinic at the University of Michigan. Her clinical and research interests focus on improving the diagnosis and treatment of Alzheimer’s disease and related disorders. Dr. Heidebrink leads the University of Michigan’s participation in the Alzheimer’s Disease Neuroimaging Initiative (ADNI). This landmark study uses brain imaging and other biomarkers to evaluate the onset and progression of Alzheimer’s disease. ADNI data support the belief that brain changes occur many years before symptoms of Alzheimer’s disease emerge. ADNI techniques will soon be used to identify persons with very early Alzheimer’s pathology, in order to study therapies that might halt the disease even before symptoms appear. Judy attended medical school at the University of Texas Southwestern and received her Neurology training at the University of Michigan.

    Joan Ilardo, PhD

    joanDr. Ilardo is the Director of the Research Initiatives at the Michigan State University College of Human Medicine’s Office of Research and the Co-Director of the Geriatric Education Center of Michigan. As the Executive Director of the Michigan Aging Education Collaborative she interacts with all the major players in the aging network throughout Michigan on a regular basis. She currently has a leadership role in several statewide initiatives related to sustaining and scaling up evidenced-based educational programs in self-management (Stanford CDSMP model), caregiver training (dementia), and advance care planning. As a member of the Michigan Commission on Services to the Aging, she serves on a 15-member commission that oversees Michigan’s implementation of the Older Americans Act through the state aging unit (Michigan Aging and Adult Services Agency) and has access to government officials and legislators involved in aging policy and services in Michigan.

    Robert Koeppe, PhD

    rad_koeppe_bobDr. Koeppe is a Professor of Radiology at the University of Michigan and the Director of the PET Physics Section of the Division of Nuclear Medicine. His research interests center around the quantitative aspects of positron emission tomography (PET). Specific research areas include the development and implementation of tracer kinetic models for new and existing positron labeled radiotracers, development of optimal techniques for estimation of physiological quantities, and development and implementation of automated image analysis routines for use with PET. Another specific area of research is the use of PET cerebral blood flow activation studies to examine various cognitive and neurological functions of the brain. Other research interests include the correlation and comparison of information obtained from PET studies to that obtained from corresponding anatomic imaging procedures such as magnetic resonance imaging.

    Kenneth Langa, MD, PhD

    Dr. Langa is a Professor in the Department of Internal Medicine and Institute for Social Research, a Research Scientist in the Veterans Affairs Center for Clinical Management Research, and an Associate Director of the Institute of Gerontology, all at the University of Michigan. He is also Associate Director of the Health and Retirement Study (HRS), a National Institute on Aging funded longitudinal study of 25,000 adults in the United States.

    Dr. Langa received an MD and PhD in Public Policy at the University of Chicago as a Fellow in the Pew Program for Medicine, Arts, and the Social Sciences. He is a board-certified General Internist with an active clinical practice treating adult patients, and he is an elected member of the American Society for Clinical Investigation (ASCI).

    Dr. Langa’s research focuses on the epidemiology and costs of chronic disease in older adults, with an emphasis on Alzheimer’s disease and other dementias. He has published more than 175 peer-reviewed articles on these topics. He is currently studying population trends in dementia prevalence, and the relationship of common cardiovascular risk factors, as well as acute illnesses such as sepsis and stroke, to cognitive decline and dementia. In 2007 and 2015, Dr. Langa was a Visiting Professor at the Institute of Public Health at the University of Cambridge, and in 2015 he was also a Visiting Professor at the World Health Organization in Geneva, Switzerland, where he continued work on cross-national comparisons of the epidemiology and outcomes of dementia in the United States, England, and other countries around the world.

    Peter Lichtenberg, PhD

    Dr. Lichtenberg is the Research Education Component Core Co-Leader of the MADC, the director of the Wayne State University Institute of Gerontology, and Co-Director of the Michigan Center for Urban African American Aging Research (MCUAAAR). He is an expert in Geriatric Psychology and a national leader in addressing health disparities in elderly minority populations. In his role at Wayne State University, Dr. Lichtenberg has founded the IOG pre-doctoral training program in aging and urban health, was the Principle Investigator on a National Institute of Aging training grant from 2001-2012, and has helped train nearly fifty doctoral students in an intensive aging research program. As the MADC Clinical Core Co-Leader, Peter has been instrumental in the MADC’s success with recruiting underrepresented minorities in Detroit.

    Andrew Lieberman, MD, PhD

    andy_liebermanDr. Lieberman is MADC Neuropathology Core Leader, Abrams Collegiate Professor of Pathology, and Director of Neuropathology at the University of Michigan. He is internationally known for his research on the mechanism of inherited degenerative brain disorders. He is passionate about understanding how brain cells “handle” the abnormal proteins that accumulate in so many brain diseases including the dementias, so that we can design rational approaches to therapy. Dr. Lieberman received his MD and PhD degrees from the University of Maryland Medical School, and completed residency training in Anatomic Pathology and fellowship training in Neuropathology at the University of Pennsylvania.

    Gulin Oz, PhD

    Dr. Gülin Öz is an associate professor in the Department of Radiology who specializes in magnetic resonance spectroscopy (MRS). Dr. Oz graduated from Bosphorus University in Istanbul, Turkey with BS degrees in Physics and Chemistry and obtained her PhD in Biochemistry at the University of Minnesota. She continued with postdoctoral training at the Center for Magnetic Resonance Research (CMRR) where she joined the faculty as assistant professor in 2006. Here she also served as the MR Core Director of the General Clinical Research Center (GCRC) from 2005-2009.

    Henry Paulson, MD, PhD

    henry_paulsonDr. Paulson directs the MADC, working closely with MADC staff to define and implement the diverse initiatives through which we fulfill our three-part mission. Dr. Paulson is also a Lucile Groff Professor of Neurology at the University of Michigan. He joined the Center as Associate Director in 2009 and assumed Directorship in 2011. He has worked for more than 20 years on degenerative brain diseases, both inherited and acquired. As a neurologist and neuroscientist, Dr. Paulson is deeply committed to translating findings from the research bench to the patient bedside. Toward that goal, he is focused on building connections between scientists, clinicians and the public, not only across the U-M campus but also across the state of Michigan. He received his MD and PhD degrees from Yale University School of Medicine and his Neurology training at the University of Pennsylvania.

    Carol Persad, PhD

    persad-600w-webDr. Persad is the Director of the Neuropsychology Clinic at the University of Michigan. This clinic conducts neuropsychological assessments on over 3,000 patents a year with a range of medical, psychiatric and neurological disorders across the lifespan, and houses a large accredited postdoctoral fellowship training program.

    Scott Roberts, PhD

    scott_robertsScott Roberts, PhD, is a Professor of Health Behavior and Health Education at the U-M School of Public Health, where he directs its certificate program in Public Health Genetics and co-directs a dual master’s degree program in Public Health and Genetic Counseling. Dr. Roberts conducts research related to health education and support services in AD and has served since 2001 as Co-PI of the NIH-funded REVEAL Study, a NIH-funded series of randomized clinical trials evaluating the impact of disclosing genetic risk information to individuals with a family history of AD. Prior to coming to U-M, Dr. Roberts served as Co-Director of the Education Core in the NIA-funded Boston University Alzheimer’s Disease Center. He now directs the MADC Outreach, Recruitment and Education Core.

    Vikram Shakkottai, MD, PhD

    Dr. Vikram Shakkottai is an Assistant Professor of Neurology at the University of Michigan School of Medicine. He is currently the director of the Michigan Brain Bank. He received his MBBS from Christian Medical College in Vellor, Tamil Nadu, India and completed his residency at Barnes-Jewish Hospital in St. Louis, Missouri. His interests include investigating changes in cerebellar physiology in ataxic disorders and determining whether ion channel modulators have a role in the treatment of movement disorders.

    Peter K Todd, MD, PhD

    Location portraits of Roman Giger, Dr. Ken Casey, Dr. Peter Todd, Dr. William Dauer, Sokol Todi, Dr. Tiffany Braley, Dr. Daniel Leventhal, Dr. Vikram Shokkotai, and Edgar Rodriguez in the BSRB (atrium and fourth floor Paulson lab) on 12/16/09.

    An Assistant Professor of Neurology and the Bucky and Patti Harris Collegiate Professor in Alzheimer’s disease at the University of Michigan, Dr. Todd explores the molecular mechanisms in neurodegenerative diseases with a particular interest in repeat expansion diseases such as the recently discovered C9ORF72 expansion underlying frontotemporal dementia. Dr. Todd is also a staff neurologist at the Ann Arbor VA Medical Center. He has worked in the field of Fragile X research for almost 20 years.

    Irving Vega, PhD

    imgresIrving E. Vega obtained his undergraduate degree in Biology from the University of Puerto Rico-Mayaguez Campus, where he was a NIH-Minority Access for Research Careers (MARC) Fellow. Then, he continued his research training in the Department of Cell Biology and Neuroscience at the Graduate School of New Brunswick, Rutgers University, earning his PhD. Dr. Vega proceeded to a postdoctoral fellowship in the Neuroscience Department at Mayo Clinic Jacksonville, where he developed his research career focusing on the identification of proteome changes associated with the accumulation of pathological tau proteins in neurodegenerative disorders such as Alzheimer’s disease. As graduate student and postdoctoral fellow, Dr. Vega was supported by different fellowships including NIH-NRSA F31 and F32. In 2005, Dr. Vega established a research team as faculty member in the Department of Biology at the University of Puerto Rico-Rio Piedras Campus. In 2014, Dr. Vega transferred his research program to the Department of Translational Science and Molecular Medicine at Michigan State University. In addition to mentor graduate students that successfully completed their PhD, Dr. Vega also has dedicated his career to develop training programs for undergraduate students in order to increase diversity in the field of neuroscience. His dedication and commitment to mentor the next generation of researchers, especially those from underrepresented ethnic groups in science, is based on his own experiences and serve as the basis for a productive research career.

    Sriram Venneti, MD

    Dr. Venneti is a clinician-scientist who expertise is in Neuropathology and the biology of brain cancer. Dr. Venneti completed his residency in Anatomic Pathology and fellowship in Neuropathology at the University of Pennsylvania followed by postdoctoral work at the Memorial Sloan Kettering Cancer Center in New York. Dr. Venneti was recruited as a faculty member to the University of Michigan in November 2014. Dr. Venneti’s research interests lie in understanding the biology of brain tumors in adults and children. The projects in the lab are highly translational and focus on integrating epigenetics, cancer metabolism and in vivo imaging techniques to investigate pathogenic mechanisms in adult and pediatric brain tumors. These studies are based on Dr. Venneti’s clinical and research expertise enabling successful translation from the bench top to the bedside. He serves on the editorial board of Brain Pathology and the Journal of Neuropathology and Experimental Neurology. Dr. Venneti is committed to teaching, mentoring and training graduate and medical students and serves as course director for the Neuropathology microscopy course held in the fall of every year.

    Jenna Wiens, PhD

    Dr. Wiens is an Assistant Professor in Computer Science Engineering (CSE) at the University of Michigan. She currently heads the MLD3 research group. Her primary research interests lie at the intersection of machine learning and healthcare. The overarching goal of her research agenda is to develop the computational methods needed to help organize, process, and transform data into actionable knowledge.

    Jieping Ye, PhD

    ye2Dr. Ye is an Associate Professor of Computational Medicine and Bioinformatics at the University of Michigan. For the last thirteen years, he has been conducting fundamental research in machine learning and data mining, developing computational methods for biomedical data analysis, and building informatics software. He leads the development of the SLEP (Sparse Learning with Efficient Projections) package, which includes implementations of large-scale sparse learning models, and the MALSAR (Multi-tAsk Learning via StructurAl Regularization) package, which includes implementations of state-of-the-art multi-task learning models. Currently, there are about 4,500 active users from over 25 different countries. With close collaboration with researchers at the biomedical field, he has successfully applied these methods for analyzing biomedical data, including clinical image data and genotype data from Alzheimer’s patients.

     

  • Internal Advisory Board

    Cathleen Connell, PhD

    University of Michigan

    cathleen_connellDr. Cathleen Connell is a Professor in the Department of Health Behavior and Health Education at the University of Michigan School of Public Health.  Her graduate training is in human development and families studies with a focus on adult development and aging; her post-doctoral training from Washington University in St. Louis is in chronic illness risk reduction.  She currently serves as Associate Director of the Center for Managing Chronic Disease.  Her research focuses broadly on families facing dementia, including community-based approaches to improve dementia service delivery, strategies to increase physical activity among spouse caregivers, attitudes and beliefs about dementia and diagnosis, and assessing the role of pets as a source of support and companionship.

    Christina Chan, PhD, MS

     Michigan State University

    christina_chan2Dr. Chan, the George W. Bissel Professor of Chemical Engineering & Materials Science, focuses on systems biology and bioinformatics, metabolic engineering, nanoparticles and drug delivery systems, cellular and tissue engineering, diabetes, cancer, Alzheimer and Parkinson’s diseases.Her group has been studying liver and neuronal/astrocyte metabolism, signaling and function, as well as the signaling and differentiation of mesenchymal stem cells.

    William Dauer, MD

    University of Michigan

    dauer_1677The central goal of Dr. Dauer’s studies is to unravel the molecular and cellular mechanisms of diseases that disrupt the motor system. His primary focus is on Parkinson’s disease and DYT1 dystonia. For each of these projects, he focuses  efforts on disease genes that cause these disorders, employing a range of molecular, cellular, and whole animal studies to dissect the normal role of disease proteins, and how pathogenic mutations lead to disease. His team currently has many studies on novel models of Parkinson’s and dystonia both in whole animals and at the cell and molecular level. They are interested in key molecular events that drive these processes, and in understanding the mechanisms underlying the selective vulnerability of certain cell types (e.g., dopamine neurons).

    Eva Feldman, MD, PhD

    Group shots and head shots of Dr. Eva Feldman and her lab staff in the BSRB on 10/2/09.Dr. Feldman’s laboratory is interested in the role of growth factors in the pathogenesis and treatment of neurologic disorders. Their research focuses on growth factor signaling mechanisms responsible for neuronal survival and differentiation. They are particularly interested in insulin-like growth I IGF-I and its receptor (IGF-IR). IGF-I and IGF-II are potent neurotrophic factors for motor and sensory neurons and glia. Dr. Feldman’s laboratory is currently investigating the role of IGF-I:IGF-IR in protecting neurons from oxidative and toxic stressors and preventing cell death in models of diabetic neuropathy, amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease. Their in vitro model systems include primary motor, sensory and cortical neurons and transformed neuronal cell lines. Animal models include wild type and transgenic mice and zebrafish. The Feldman laboratory uses a wide range of techniques including transient and stable neuronal transfection, message knock down using siRNA, injection of morpholinos into zebrafish, protein analyses including western immunoblotting, dot blotting and ELISA, biochemistry and oxidative adduct measures including substrate analyses and enzyme activity and anatomical assays including immunohistochemistry, histochemistry and transmission electron microscopy. The laboratory currently includes clinician and basic scientists, postdoctoral fellows, graduate and undergraduate students and technicians all of whom are actively engaged as research teams focused on a particular aspect of neurological disease.

    Kirk Frey, MD

    freyDr. Frey is internationally recognized for his use of brain imaging techniques to understand and diagnose cognitive and movement disorders.  He oversees multiple studies that use PET imaging to improve our ability to diagnose different forms of dementia.

    Vincent Groppi, PhD

    University of Michigan

    vincent-groppiVincent Groppi, a leader in pharmaceuticals and biotechnology, has assumed the position of director of the University of Michigan’s Center for the Discovery of New Medicines.

    James Jackson, PhD

    University of Michigan

    jackson_james_150James S. Jackson is the Daniel Katz Distinguished University Professor of Psychology, professor of health behavior and health education in the School of Public Health, and director and research professor of the Institute for Social Research. He is the past chair of the social psychology training program and director of the Research Center for Group Dynamics, the Program for Research on Black Americans, and the Center for Afroamerican and African Studies, all at the University of Michigan.

    Helen Kales, MD, PPA

    University of Michigan

    kales-websiteHelen Kales, MD PPA, is Professor of Psychiatry and Director of the Program for Positive Aging at the University of Michigan. She is also Associate Director for Mental Health and Aging Research, the University of Michigan Geriatrics Center, Research Scientist, VA Center for Clinical Management Research, and Research Scientist, Geriatric Research Education and Clinical Center VA Ann Arbor Healthcare System.Dr. Kales is recognized as an expert in outcomes related to depression in later life as well as those associated with neuropsychiatric symptoms of dementia, and in pharmacoepidemiology research related to the use of antipsychotics in the elderly. Her research program is directly informed by her clinical work and experiences with patients, families, providers and systems to diminish the barriers to effective and quality care for older patients with mental health issues.

    Susan Maixner, MD

    Susan Maixner, MD, is a Clinical Associate Professor in the Department of Psychiatry, and directs both the Geriatric Psychiatry Program and the Geriatric Psychiatry Fellowship Program.  Dr. Maixner’s interests include geriatric mental health issues, geriatric dual diagnosis, dementia, and behavioral disturbances in dementia.  She graduated from medical school from the University of Nebraska in 1993.  Dr. Maixner works closely with the Michigan Alzheimer’s Disease Center in research and on Rinne LBD Initiative activities.

    Carlos Mendes de Leon, PhD

    University of Michigan

    mendesdeleon_carlos_150Dr. Mendes de Leon is a social epidemiologist with a primary interest in the major health problems and health disparities in late life. His work focuses on a broad array of social and psychological determinants that affect the development and progression of disability, cognitive decline and other common, age-associated health conditions. Specific areas of interest include the role of neighborhood-level social processes and environments in late-life health, and the complex interplay between life-course social conditions and biological processes and their functional consequences in older age. His current studies focus on the role of neighborhood contexts and inflammatory processes in social disparities in late-life disability and cognitive impairment. In other research, he is investigating the cumulative and interactive effects of racial background and life-course socio-economic disadvantage in subclinical disease and disability in older adults.

    Naftali Raz, PhD

    Wayne State University

    sept-2015-269Dr. Raz completed his undergraduate studies at Hebrew University in Jerusalem, Israel, in 1979. He was trained in psychology and human neuroscience at the University of Texas at Austin, and received his Ph.D. in 1985. Dr. Raz’s research focuses on the neural correlates and modifiers of cognitive aging. His research has been continuously supported since 1993 by the National Institute on Aging.

    Raymond Yung, MB, ChB

    University of Michigan

    Dr. Raymond Yung is a professor of Internal Medicine and a research scientist at the Veterans Affairs Ann Arbor Geriatric Research, Education and Clinical Center. He obtained his medical school training from the University of Liverpool in England (1986). After completing an internal medicine residency at Sinai Hospital in Detroit, he received further clinical and research fellowship training in Rheumatology (1994) and Geriatric Medicine (1996) at the University of Michigan, where he has since remained a faculty member. Dr. Yung is a recipient of the NIH Individual National Research Service Award (1994-1996) and Clinical Investigator Award (1997-2002), and the American Federation for Aging Research Paul Beeson Physician Faculty Scholars in Aging Research Award (1998-2001). In addition, he has received the American College of Rheumatology Senior Rheumatology Scholar Award (1994). He is currently funded by the NIH in his research effort on the effects of aging on T cell chemokine function. In addition to his research endeavor, Dr. Yung is also the Director of the Musculoskeletal Sequence in the Medical School curriculum. Dr. Yung was named chief, Division of Geriatric and Palliative Medicine and co-director, Geriatrics Center in 2011.

    Consultants

    David Burke, PhD

    Clinical Core Consultant — University of Michigan

    David Burke, PhD, is a Professor of Human Genetics and a Clinical Core Consultant for the MADC. His research interests include the development of low cost, single nucleotide variant DNA and RNA testing methods which are employed by the MADC in genetic risk factor assessment. The robust methods are currently used in the laboratory to perform over ten thousand human, mouse, viral and bacterial SNP genotypes per year.
    Gulin Oz, PhD

    Clinical Core Consultant — University of Minnesota

    Dr. Gülin Öz is an associate professor in the Department of Radiology who specializes in magnetic resonance spectroscopy (MRS). Dr. Oz graduated from Bosphorus University in Istanbul, Turkey with BS degrees in Physics and Chemistry and obtained her PhD in Biochemistry at the University of Minnesota. She continued with postdoctoral training at the Center for Magnetic Resonance Research (CMRR) where she joined the faculty as assistant professor in 2006. Here she also served as the MR Core Director of the General Clinical Research Center (GCRC) from 2005-2009.

    Charles Burant, MD, PhD

    Clinical Core Consultant — University of Michigan

    Dr. Burant directs a research program that integrates molecular phenotyping (including metabolomics) with dietary, clinical and behavioral phenotypes to understand the development of obesity, insulin resistance and diabetes. He has a specific interest in intermediary metabolism and he has integrated metabolomics with other technologies to gain a more complete understanding of cellular metabolism. Dr. Burant directs the Michigan Regional Comprehensive Metabolomics Resource Core (U24), which is one of six NIH-funded metabolomics centers. At the MADC, he provides advice on the use of metabolomics profiling to gain insights into the pathophysiology of neurodegenerative diseases and the potential relationship to metabolic syndrome, obesity, diabetes and other metabolic states.

    Irving Vega, PhD

    Research Education Core Consultant — Michigan State University

    Irving E. Vega obtained his undergraduate degree in Biology from the University of Puerto Rico-Mayaguez Campus, where he was a NIH-Minority Access for Research Careers (MARC) Fellow. Then, he continued his research training in the Department of Cell Biology and Neuroscience at the Graduate School of New Brunswick, Rutgers University, earning his PhD. Dr. Vega proceeded to a postdoctoral fellowship in the Neuroscience Department at Mayo Clinic Jacksonville, where he developed his research career focusing on the identification of proteome changes associated with the accumulation of pathological tau proteins in neurodegenerative disorders such as Alzheimer’s disease. As graduate student and postdoctoral fellow, Dr. Vega was supported by different fellowships including NIH-NRSA F31 and F32. In 2005, Dr. Vega established a research team as faculty member in the Department of Biology at the University of Puerto Rico-Rio Piedras Campus. In 2014, Dr. Vega transferred his research program to the Department of Translational Science and Molecular Medicine at Michigan State University. In addition to mentor graduate students that successfully completed their PhD, Dr. Vega also has dedicated his career to develop training programs for undergraduate students in order to increase diversity in the field of neuroscience. His dedication and commitment to mentor the next generation of researchers, especially those from underrepresented ethnic groups in science, is based on his own experiences and serve as the basis for a productive research career.

    Neil Alexander, MD, MS

    Research Education Core Consultant — University of Michigan

    Dr. Alexander graduated from the University of Minnesota Medical School, Minneapolis and received a clinical research design and biostatistics master’s degree from University of Michigan. He completed his internal medicine residency at the University of New Mexico Affiliated Hospitals and a geriatrics fellowship at the University of Michigan. He is a past research fellow at the University of Michigan Institute of Gerontology. Dr. Alexander is board-certified in internal medicine and geriatrics. He has a special interest in exercise, mobility, falls and rehabilitation in older adults. He is the Director of the VA Ann Arbor Geriatric Research Education and Clinical Center.

    Jenna Wiens, PhD

    Data Management and Statistical Core Consultant — University of Michigan

    Dr. Wiens is an Assistant Professor in Computer Science Engineering (CSE) at the University of Michigan. She currently heads the MLD3 research group. Her primary research interests lie at the intersection of machine learning and healthcare. The overarching goal of her research agenda is to develop the computational methods needed to help organize, process, and transform data into actionable knowledge.

    Robert Koeppe, PhD

    Data Management and Statistical Core Consultant - University of Michigan

    Dr. Koeppe is a Professor of Radiology at the University of Michigan and the Director of the PET Physics Section of the Division of Nuclear Medicine. His research interests center around the quantitative aspects of positron emission tomography (PET). Specific research areas include the development and implementation of tracer kinetic models for new and existing positron labeled radiotracers, development of optimal techniques for estimation of physiological quantities, and development and implementation of automated image analysis routines for use with PET. Another specific area of research is the use of PET cerebral blood flow activation studies to examine various cognitive and neurological functions of the brain. Other research interests include the correlation and comparison of information obtained from PET studies to that obtained from corresponding anatomic imaging procedures such as magnetic resonance imaging.

    Peter Todd, MD, PhD

    Neuropathology Core Consultant - University of Michigan

    An Assistant Professor of Neurology and the Bucky and Patti Harris Collegiate Professor in Alzheimer’s disease at the University of Michigan, Dr. Todd explores the molecular mechanisms in neurodegenerative diseases with a particular interest in repeat expansion diseases such as the recently discovered C9ORF72 expansion underlying frontotemporal dementia. Dr. Todd is also a staff neurologist at the Ann Arbor VA Medical Center. He has worked in the field of Fragile X research for almost 20 years.

    Peter Lichtenberg, PhD

    Outreach and Recruitment Core Consultant - Wayne State University

    Dr. Lichtenberg is the Research Education Component Core Co-Leader of the MADC, the director of the Wayne State University Institute of Gerontology, and Co-Director of the Michigan Center for Urban African American Aging Research (MCUAAAR). He is an expert in Geriatric Psychology and a national leader in addressing health disparities in elderly minority populations. In his role at Wayne State University, Dr. Lichtenberg has founded the IOG pre-doctoral training program in aging and urban health, was the Principle Investigator on a National Institute of Aging training grant from 2001-2012, and has helped train nearly fifty doctoral students in an intensive aging research program. As the MADC Clinical Core Co-Leader, Peter has been instrumental in the MADC’s success with recruiting underrepresented minorities in Detroit.

  • Key Links at the University of Michigan

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