For Professionals

Andrew Brouwer, PhD, MS, MA (University of Michigan, Assistant Research Scientist) develops and uses computational epidemiology to enhance our understanding of the complex patterns and dynamics that underlie disease data, as well as the implications of those patterns for public health practice. Systems thinking is a fundamental theoretical framework in epidemiology, and Dr. Brouwer uses it to bring new insights about the population-level implications of transmission processes, disease etiology and progression, and behavior. Dr. Brouwer's work is data-driven, focused on developing models for inference in epidemiology and public health. His s work is united by the use of mechanistic frameworks as a lens to interpret real data, a focus on longitudinal patterns and dynamics, and by a quantitative toolset that includes compartmental differential equation models, stochastic multistate transition models, age–period–cohort models, among others. He is an expert in methods that address questions of parameter identifiability, estimation, and uncertainty.

Elizabeth Litkowski, PhD (University of Michigan) is a postdoctoral research fellow in the Kaczorowski Lab who returned to graduate school after a diverse background in technology businesses.  She holds a B.S. in Mathematics and an MBA which enabled her to hold roles in businesses as varied as electronic component supply chain distribution to oil/gas drilling before moving to work with theoretical statisticians.  Upon returning to school, she completed an MS degree in Biostatistics evaluating gene networks perturbed by ethanol exposure in a LXS mouse panel to identify potential targets for treating alcohol addiction.  In her PhD in genetic Epidemiology, she studied the genetic risk between diabetes and dementia in the Million Veteran Program (MVP), a large biobank of U.S Veterans with clinical and genotype data. Using a technique called Mendelian randomization, she found evidence of causality between diabetes and dementia in MVP.  In her postdoctoral research, she is pursuing the next step of the diabetes-dementia link through analysis of glucose tolerance with cognitive impairment in a gene by diet study in a mouse panel intended to emulate human diversity.

Norman Scheel, Dr. rer. nat. (Ph.D.), Dipl.-Inf. (Michigan State University, Postdoctoral Fellow, Research Associate) is on the cutting edge of multi-disciplinary academic training, the prestigious University of Lübeck, Germany allowed me to pursue my education at the cross-sections of computer science, medical informatics, and medicine. Connecting the fields of medical imaging and data science was my core interest during my higher academic education. With great pride, I received a German Diploma in Informatics (Dipl.-Inf., comparable to a combined B.S. and M.S. degree) under the supervision of Prof. Dr.-Ing. Dr.med.habil. Siegfried J. Pöppl († 2019), a visionary and early spearhead in medical image computing in Germany. My doctoral education focused on computational neuroscience at the Graduate School for Computing in Medicine & Life Sciences, University of Lübeck, Germany, for which I received a very prestigious Scholarship from the German Universities Excellence Initiative. Under the supervision of Prof. Dr.rer.nat. Amir Madany Mamlouk, (Institute for Neuro- and Bioinformatics and Center of Brain, Behavior, and Metabolism (CBBM), University of Lübeck, Germany), I evaluated machine learning methods on resting-state functional MRI data, especially in high dimension - low sample size scenarios. As advanced machine-learning approaches proved to be very sensitive towards noise and confounds in functional MRI data, a great amount of my doctoral research focused on artifact removal strategies and their effects on machine-learning-derived biomarkers. In my postdoctoral fellowship at the Department of Neurology, University Medical Center Schleswig-Holstein, Germany, I further investigated a method to measure the dimensional complexity of resting-state functional MRI recordings of the human brain and found significant changes in the complexity of brain function due to healthy aging. Based on this finding I was awarded a developmental grant to test the dimensional complexity of resting-state fMRI data as a biomarker for Alzheimer’s disease, by the Michigan Alzheimer’s disease research center (MADRC). In my postdoctoral time at Michigan State University, I have been able to work closely with Dr. David Zhu, and a multi-disciplinary multi-university team, co-leading the imaging cores of major NIH R01 clinical trials investigating the underpinning relationships of hypertension and the development of Alzheimer’s disease. All throughout my postgraduate career I have been teaching and mentoring students in the many aspects of data- and neuroscience and am proud that I was recently awarded Michigan State University’s 2023 Postdoctoral Excellence in Teaching and Mentoring Award.

Elisa Torres, PhD, RN (Wayne State University) is an Associate Professor at Wayne State University, College of Nursing. Dr. Torres’ program of research involves physical activity and the brain. Her current research aims to determine if biological aging is a mechanism by which physical activity is associated with less risk for Alzheimer’s disease.

Connie Wu, Ph.D. (University of Michigan) is a Research Assistant Professor in the Life Sciences Institute and an Assistant Professor in the Departments of Biomedical Engineering and Pharmaceutical Sciences at the University of Michigan. Her lab launched in January 2023 and focuses on (1) the development and translation of ultrasensitive single-molecule detection technologies for diagnostic applications in Alzheimer’s disease and cancer; and (2) multifunctional RNA therapeutics for cancer immunotherapy. Connie obtained her B.S. in chemical engineering from Yale University, where she worked with Dr. Paul Van Tassel in designing porous layer-by-layer polymer films for tissue engineering applications. She pursued her Ph.D. in chemical engineering at MIT in Dr. Paula Hammond’s lab, where she engineered a highly potent small interfering RNA (siRNA) nanoparticle delivery system via nucleic acid engineering and polymer chemistry approaches. She then transitioned to the diagnostics field for her postdoctoral research in the lab of Dr. David Walt at Brigham and Women’s Hospital and the Wyss Institute at Harvard University, where she pioneered ultrasensitive single-molecule detection methods that can measure attomolar (10^-18 M) protein concentrations with versatile multiplexing capabilities. In parallel, she developed ultrasensitive digital assays for detecting the long-interspersed element-1 (LINE-1) retrotransposon-encoded protein ORF1p in blood as a highly specific multi-cancer biomarker. Connie is a Biological Sciences Scholar at the University of Michigan and was the recipient of multiple fellowships during her Ph.D. and postdoctoral training, including an NSF Graduate Research Fellowship, MIT Presidential Fellowship, and NIH Ruth L. Kirschstein F32 Postdoctoral Fellowship.

Arthur Zhou, Ph.D. (University of Michigan) is a Postdoctoral Research Investigator in the Department of Computational Medicine and Bioinformatics at the University of Michigan. His primary research interest is the discovery and analysis of structural genomic variation within human populations and its impact on health and disease. Structural variations (SVs) have long been known to shape population diversity and lead to many genetic disorders. By combining bioinformatics pipelines and the data from variable genomic technologies, we can explore the SVs' origins, distribution, and mutational processes. An outstanding problem in the field is that many SVs are potentially overlooked, lying in complex genomic regions that hinder the discovery by traditional methodologies and bioinformatics pipelines. One category of genomic variation, repetitive retrotransposable elements, is of particular interest to my current research. By developing novel analytical tools and leveraging cutting-edge genomic technologies, particularly the emerging long-read sequencing technologies, we can penetrate these intricate regions and resolve these cryptic SVs as we have never done before.

Dr. Kelly DuBois joined the MSU Department of Translational Neuroscience as a postdoctoral fellow in the summer of 2021. She graduated with a B.S. in Biotechnology from Calvin University, after which she completed a Ph.D. in Biomedical Science at the University of California, San Francisco. She then completed a Postdoctoral Fellowship in the Department of Pathology at Cambridge University in the UK, where she studied molecular parasitology. Her current research aims include development of blood-based assays for the detection of Alzheimer’s disease and other tauopathies.

Dr. Alexandru Iordan completed his Ph.D. in Neuroscience at the University of Illinois, Urbana-Champaign. He joined the University of Michigan in 2016 as a Postdoctoral Fellow and is currently an Assistant Research Scientist in the Department of Psychology. Dr. Iordan’s research aims to clarify the neural mechanisms underlying cognitive plasticity in healthy and pathological aging by combining multimodal imaging with training and neuromodulation. His interests converge toward developing and applying non-pharmacological treatments with measurable neurobiological outcomes for Alzheimer's Disease and related dementias.

Tongtong Li received her Ph.D. degree in Electrical and Computer Engineering in 2000 from Auburn University, and her Ph.D. degree in Math in 1995 from Sun Yat-Sen University. From 2000 to 2002, she was with Bell Labs, and had been working on the design and implementation of 3G and 4G systems. Since 2002, she has been with the Department of Electrical and Computer Engineering at Michigan State University, where she is now a Professor. Professor Li's research interests fall into the areas of wireless and wired communications, wireless security, information theory and statistical signal processing, and brain network analysis using communication theory, with applications to Alzheimer’s disease and related research.

She has been working on the modeling and analysis of brain information processing capacity, input storage capacity, neuronal activity, functional connectivity, causality, stability, and the impact of age and cognitive impairment on brain network functions and performances. In particular, by using tools in communication theory, artificial intelligence (AI) and machine learning, she has been working on non-invasive biomarker development for the early diagnosis and prediction of Alzheimer’s disease (AD), and effect analysis of different interventions on dementia.

Her research has been continuously supported by National Science Foundation. She was a recipient of the NSF CAREER Award (2008). Prof. Li served as an Associate Editor for IEEE Signal Processing Letters from 2007-2009, and an Editorial Board Member for EURASIP Journal Wireless Communications and Networking from 2004-2011. She served as an Associate Editor for IEEE Transactions on Signal Processing from 2012-2016.

Pilar Rivero-Rios, Ph.D., earned her master’s and doctorate degrees from the University of Granada, Spain. As a graduate student, she investigated how pathogenic mutations in LRRK2, the main genetic determinant of Parkinson’s disease, alter intracellular vesicular trafficking. As a postdoctoral researcher in the U-M Life Sciences Institute, Dr. Rivero-Rios is investigating how altered vesicular trafficking in neurons leads to synaptic loss and Alzheimer’s disease.

Xin Wang, Ph.D., M.P.H is a Research Investigator in the Department of Epidemiology at the University of Michigan School of Public Health. Dr. Wang received his M.P.H. and Ph.D. in Epidemiologic Science from the University of Michigan. His research interests broadly relate to combining epidemiological methodology with the development and application of novel data-driven approaches to systematically evaluate various environmental factors with aging-related diseases, including Alzheimer's disease and cardiometabolic disorders. His work also applies advanced statistical and machine learning approaches to build risk prediction modeling of aging-related diseases and their related mortality. He works with several ongoing cohort studies, including the Study of the Environment and Alzheimer's Disease and Related Dementias (SEAD), the Study of Women's Health Across the Nation (SWAN), Normative Aging Study (NAS), and the Nurses' Health Study (NHS).

Dr. Bender earned his Ph.D. in Behavioral and Cognitive Neuroscience from the Department of Psychology at Wayne State University in 2014, followed by a year-long postdoctoral appointment with the Institute of Gerontology. In 2018, he completed a three-year postdoctoral fellowship in Lifespan Development at the Max Planck Institute for Human Development in Berlin, Germany, before joining the departments of Epidemiology-Biostatistics and Neurology-Ophthalmology at MSU. Trained as a cognitive neuroscientist, with a broad focus on lifespan development and aging, and quantitative methods, Dr. Bender’s work seeks to understand how individual differences in vascular, metabolic, and lifestyle risk factors contribute to changes in the brain’s structure and function in normal aging and in dementia.

Dr. Benskey joined the Faculty in the Department of Translational Neuroscience as a Research Assistant Professor in Fall of 2016.  Dr. Benskey received undergraduate training in Psychology and Neuroscience at Central Michigan University, after which he completed a Ph.D. in Neuroscience at Michigan State University. He then completed a Postdoctoral Fellowship in the Department of Translational Neuroscience at Michigan State University where he studied the molecular neurobiology of Parkinson’s Disease, with a specific focus on how viral vectors can be used to both model and potentially treat neuropathology. Dr. Benskey’s current research aims to understand the role that neuro-immune interactions play in Parkinson’s disease and Alzheimer’s disease. Outside of the lab he enjoys painting, playing the guitar and wandering in the woods with his dogs.

Dr. Sarah Elzinga’s goal is to understand how immune system pathways respond to damage at the cellular level to promote inflammation and injure the nervous system, and she is utilizing multiple models to examine nervous system injury and cognitive decline. One model includes a novel 3D culture system, developed in collaboration with the University of Michigan’s bioengineering department, that is increasing our understanding of how the different cell types in the nervous system interact. Additionally, work in other model systems has begun to uncover the underlying mechanisms and present possible treatment options for brain and nerve injury secondary to diabetes and obesity.

Dr. Finlay uses qualitative, geospatial, and mixed methods to investigate the role of built, social, natural, and microbial environments for health in later life. Her current research focuses on how neighborhood built and social environments may slow rates of cognitive decline and reduce the risk for Alzheimer's disease and dementia. She also investigates psychosocial and behavioral impacts of the COVID-19 pandemic on the physical, mental, and cognitive health of older adults.

Dr. Omar Ahmed received both his undergraduate and Ph.D. degrees in Neuroscience from Brown University. He then worked on large-scale single-neuron-resolution recordings in epilepsy patients at Massachusetts General Hospital during his postdoctoral work, before joining the faculty at the University of Michigan in 2016 as an Assistant Professor. His primary appointment is in the Dept. of Psychology (Behavioral Neuroscience area), and he is affiliated with the Dept. of Biomedical Engineering and the Neuroscience Graduate Program. His lab uses a combination of in vivo and slice electrophysiology, two-photon imaging, computational modeling and design of novel analytical tools to understand the neural circuits involved in learning and memory, as well as how these circuits are altered in Alzheimer's disease and epilepsy.

Dr. Ana Daugherty is an Assistant Professor at Wayne State University, jointly appointed in the Departments of Psychology, Psychiatry and Behavioral Neurosciences, and the Institute of Gerontology. She earned a doctorate in psychology (behavioral and cognitive neuroscience) from Wayne State University in 2014 and completed a competitive post-doctoral research fellowship at the Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign. She now directs the Healthy Brain Aging laboratory and studies how vascular and metabolic factors modify human neural cognitive aging, and contribute to risk for Alzheimer’s disease and related dementia. She employs multimodal MRI methods, diverse cognitive-behavioral assessments, blood biomarkers of vascular health, actigraphy and advanced statistical methods for the longitudinal study of aging.

Dr. Amara Ezeamama is an Assistant Professor with a decade of experience implementing epidemiologic studies of cognitive function in relation to HIV-infection, parasitic infection and malnutrition in vulnerable populations within resource limited settings. She obtained a Ph.D. in Epidemiology from Brown University in 2006 and completed a post-doctoral fellowship at the Harvard School of Public health between 2008 and 2012.  Prior to graduate training in epidemiology, she obtained a Bachelor’s degree in Neuroscience from the University of California Los Angeles (UCLA Class of 2000).  In her current role, she investigates determinants of neurocognitive disorder, disability and quality of life decline among Africans living with HIV and currently on antiretroviral therapy.  She hopes to inform future interventions that mitigate premature functional decline in this vulnerable population.

Dr. Charlie Fehl is a chemical biologist studying the molecular mechanisms of sugar metabolism and signaling pathways. His lab builds controllable intracellular tools (using light or synthetic biology) to interrogate metabolic regulation in living cells. In particular, we study the neuroprotective effects of O-GlcNAcylation, a metabolic signal that drops precipitously in neurons experiencing degeneration. We use organic synthesis, photochemistry, and synthetic biology to track the roles of these sugars in living cells using proteomics, transcriptomics, and informatics analyses to gain a systems-wide understanding of metabolic regulation in neurodegenerative disease. Dr. Fehl received his B.S. degree from the University of Michigan, then took an extended route back to Detroit following a Ph.D. in Medicinal Chemistry at the University of Kansas and postdoctoral experience at the University of Oxford. He opened his lab in the Wayne State University Department of Chemistry in 2018.

Ilce Medina Meza is Assistant Professor at the Department of Biosystems and Agricultural Engineering at Michigan State University. She is a Chemical Engineer B.S. and M.S. with Ph.D. in Food Science from Instituto Tecnologico de Veracruz/Universita di Bologna. Prior to joining MSU, she was appointed as research fellow in the Biological Systems and Engineering department at Washington State University. Her research interest is on Food and Health Engineering, focusing on a deep understanding of the molecular mechanisms governing oxidative stress of lipids, steroids and cholesterol homeostasis. She has devoted significant time studying lipid oxidation due to autooxidation and reactive oxygen species (ROS), and evaluating their impact on health. Her current research is the lipidomic based-discovery of neurodegenerative disease biomarkers for early detection by application of high throughput mass spectrometry methods and kinetic modeling. She has joint appointments in the departments of Chemical and Biomedical Engineering. She has published more than 30 peer-reviewed papers. She is the editor of 1 book, author of 2 book chapters, and delivered more than 40 presentations both oral and poster at international conferences. She is a member of the ASABE, IFT and European Network for Oxysterols Research (ENOR). She is a member of the Editorial Board of the journal Food Research International, and serves as reviewer for several peer-reviewed journals in the area, including Food Engineering, Food Chemistry, Food and Bioprocess Technology.

Dr. Polenick is Assistant Professor in the U-M Department of Psychiatry and Faculty Associate in the Aging & Biopsychosocial Innovations Program of the Survey Research Center at the U-M Institute for Social Research. She received her Ph.D. in Human Development and Family Studies from the Pennsylvania State University, and she completed an NIMH T32 postdoctoral fellowship focused on geriatric mental health in the U-M Department of Psychiatry. Dr. Polenick’s research centers on later-life family relationships and caregiving in the context of complex care needs including dementia and multimorbidity. She is particularly interested in understanding mutual influences within older couples managing chronic conditions that inform targeted dyadic interventions to maintain the well-being of both partners.

Dr. Annalise Rahman-Filipiak is a Clinical Lecturer in the Neuropsychology Section of the Department of Psychiatry at the University of Michigan Medical School. She earned her Bachelor of Science in Psychology, Biology, and Neuroscience from the College of Charleston in Charleston, SC, followed by Master's and doctoral degrees in Clinical Psychology at Wayne State University in Detroit, MI. She was a predoctoral trainee at the Wayne State University Institute of Gerontology. Dr. Rahman-Filipiak completed a residency in Neuropsychology at the VA Ann Arbor Healthcare System/University of Michigan consortium before joining the U-M faculty in October 2018. Dr. Rahman-Filipiak's research focuses on the development of novel measures for the early detection of Alzheimer's disease and related dementias (ADRD), metacognition in aging, and culturally-sensitive protocols for the disclosure of diagnosis of or biomarker-based risk for ADRD.

DeAnnah Byrd, Ph.D. is a postdoctoral to faculty transition scholar at Wayne State University’s Institute of Gerontology. Her research focuses on understanding racial disparities in cognitive health outcomes over the adult life course. In particular, Dr. Byrd examines trajectories of cognitive functioning among black and white adults in the United States who are as young as 25, with the goal of teasing apart the psychosocial factors that contribute to these disparities, as well as identifying the optimal time in the life course to intervene. Dr. Byrd received her BS in Biology and MS in Population Health Sciences from the University of Wisconsin, Madison, WI, before participating in a Population Health fellowship at the University of Wisconsin, Madison, WI. Dr. Byrd completed her Ph.D. in Community Health Sciences in the Fielding School of Public Health at the University of California, Los Angeles.

Julia E. Gerson, Ph.D. is a post-doctoral fellow at the Paulson Laboratory, located within the Department of Neurology at the University of Michigan. Her work focuses on defining the role of a key quality control protein, UBQLN2, in the age-related neurodegenerative disorders known as synucleinopathies and tauopathies. Dr. Gerson’s work investigates how UBQLN2 interacts with tau and α-synuclein to regulate their levels in disease using cell culture and novel animal models. These studies are expected to yield new insights into the role of UBQLN2 in common age-related neurodegenerative diseases that will suggest routes to therapeutic intervention. Dr. Gerson received her BS in Psychology and Biology from Arizona State University, Tempe, AZ and her Ph.D. in Neuroscience from the University of Texas Medical Branch, Galveston, TX.

Lenette M. Jones, Ph.D., R.N., ACNS-BC is an Assistant Professor within the Department of Health Behavior and Biological Sciences at the University of Michigan School of Nursing. Dr. Jones’ research is focused on uncovering the mechanisms – biological, psychological, social, and physical – of self-management interventions. She uses neuroimaging (fMRI) to explore the neuroprocesses associated with self-management behaviors, such as diet, exercise, and medication-taking. She also examines how health information behavior (seeking, sharing, and use) can be enhanced to support blood pressure self-management. In her current studies, Dr. Jones is designing and pilot-testing interventions to improve self-management of blood pressure among African American women. Dr. Jones received her B.S., M.S., and Ph.D. in Nursing from the University of Michigan, Ann Arbor, MI.

Rohit Marawar, M.D. is an Assistant Professor of Neurology at Wayne State University. Dr. Marawar’s expertise and training is in the field of epilepsy. Recently, he transitioned his focus into hyperexcitable brain networks in cognitively normal and abnormal elderly – including those with Alzheimer’s disease and related dementias. Dr. Marawar contributed to the development of the Geriatric Epilepsy Clinic at Wayne State University-Detroit Medical Center, and long-term, hopes to play a leading role in the field of geriatric epilepsy and neurodegenerative disease. Dr. Marawar obtained a Bachelor of Medicine / Bachelor of Surgery from the Government Medical College and Hospital Nagpur in Maharashtra, India. Dr. Marawar’s postgraduate training includes Neurology residency at Albany Medical Center, Albany, NY and a Clinical Neurophysiology / Epilepsy fellowship from the David Geffen School of Medicine at the University of California, Los Angeles.

Sheria G. Robinson-Lane, Ph.D., R.N. is an Assistant Professor in the Department of Systems, Populations and Leadership at the University of Michigan School of Nursing. Dr. Robinson-Lane has focused her career on the care and support of older adults with cognitive and/or functional disabilities. She is interested in the ways that older adults adapt to changes in health, and particularly how adaptive coping strategies affect health outcomes. Her research is focused on reducing health disparities for minority older adults with cognitive impairments and their caregivers. Dr. Robinson-Lane received her B.S.N. from the University of Wisconsin, Oshkosh, WI, her M.S.N. / M.H.A. from the University of Phoenix, Phoenix, AZ, and her Ph.D. from Wayne State University, Detroit, MI. Dr. Robinson-Lane conducted her post-doctoral fellowship at the University of Michigan Medical School, Ann Arbor, MI.

Dr. Choi is an Assistant Research Scientist in the Department of Internal Medicine at the University of Michigan. Her expertise includes health and family economics and demography by training. Dr. Choi’s research extensively examines inter-relationships among older adults’ health, family, and contextual factors, and trends in older adults’ functional and activity limitations. More recently, her research interest also includes healthcare utilization and healthcare costs of Alzheimer’s disease and related dementia (ADRD). In particular, Dr. Choi is interested in the influence of family-care availability on healthcare utilization by older adults with ADRD, and in assessing the full array of ADRD care costs to individuals, family caregivers, and the public.

Dr. Combs is a research assistant professor in Michigan State University's College of Human Medicine. He studies the tau protein in order to better understand its role in the initiation and progression of Alzheimer's disease and other related dementias. His work focuses on the protein's function in regulating axonal transport in neurons and how pathological forms of tau can disrupt this process leading to neurodegeneration and toxicity in disease. By gaining a better understanding of the molecular mechanisms that underpin tau's role in Alzheimer's disease he hopes to identify better targets for future potential therapies. Combs graduated from Iowa State University with a B.S. in Electrical Engineering and the University of Kansas with a Ph.D. in Molecular, Cellular, and Developmental Biology before working as a postdoctoral research associate in Nicholas Kanaan's lab at Michigan State University.

Dr. Damoiseaux is an Assistant Professor in the Institute of Gerontology and the Department of Psychology at Wayne State University. Her main research goal is to understand the changes in brain function and cognition that accompany normal and abnormal aging. She is particularly interested in examining the influence of biological and cognitive predisposition on cognitive and brain network connectivity changes in healthy older adults. The primary approach Dr. Damoiseaux uses to study brain network connectivity is functional magnetic resonance imaging (fMRI). In addition, she uses other neuroimaging techniques, such as structural MRI and diffusion tensor imaging (DTI) to study brain structure and structural brain connectivity.

Dr. Tarraf is an assistant professor at the Institute of Gerontology and in the Department of Healthcare Sciences, and a faculty in the Masters of Public Health program in the Department of Family Medicine and Public Health Sciences at Wayne State University. He is a health services researcher, policy analyst, and gerontologist with a primary interest in research on minority aging and racial/ethnic healthcare disparities. His research evaluates disparities in health, health behavior, and healthcare access and use among race/ethnic minorities in the United States, and investigates the social determinants of health and healthcare. Dr. Tarraf has served as a principal investigator or co-investigator and statistical consultant on several university and federally funded projects.

Dr. Zhou is an assistant professor at the Department of Computer Science and Engineering at Michigan State University. Before joining MSU, Zhou received his Ph.D. degree in computer science at Arizona State University in 2014. He has a broad research interest in large-scale machine learning and data mining, and biomedical informatics. Especially, Dr. Zhou is interested in building high-performance machine learning models that understand Alzheimer's progression and identify signaling biomarkers from multiple data sources, including medical imaging, genotypes, and other clinical information.

Dr. Gideon Rothschild, Assistant Professor, Department of Psychology, University of Michigan

Project Narrative: Studies in recent years have found that sleep disturbances, which are highly prevalent in the adult population, are a risk factor for the development of cognitive decline and Alzheimer’s disease (AD). However, the brain mechanisms by which sleep disturbances could promote cognitive decline remain unresolved. In this proposal, we aim to directly address this knowledge gap in mouse animal models by recording and manipulating neural activity in the hippocampus- a critical brain region for memory- as mice experience chronic sleep disturbances that model the human condition. Our overarching goal is to elucidate the neural mechanisms linking sleep disturbances, aberrant hippocampal activity and development of AD, with the hope of promoting novel therapeutic and prevention approaches for AD, which are in dire need.

Norman Scheel, Dr. rer. nat. (Ph.D.), Dipl.-Inf., Department of Radiology, College of Human Medicine, Michigan State University

Narrative description: Even though functional resting-state MRI was first introduced more than two decades ago, it is still difficult to derive the global complexity of brain function from these recordings. In our early-stage research, introducing dimensional complexity measures to resting-state fMRI, we found significant changes in the complexity of brain function due to healthy aging. In this development project, we aim to lay the groundwork to establish dimensional complexity as a marker for cognitive elasticity, as it might prove to be valuable in diagnostics and the prediction of cognitive decline in dementia and Alzheimer’s Disease.

Weichen Zhou, Ph.D., Research Investigator, Department of Computational Medicine and Bioinformatics, University of Michigan

Project Narrative: This project, entitled ‘Explore the functional impact of transposable elements in Alzheimer’s disease and related dementias’, is proposed by Weichen Zhou (Research Investigator) and Ryan E. Mills (Associate Professor) at the Department of Computational Medicine and Bioinformatics, University of Michigan Medical School. It seeks to explore the connection between the somatic transposable elements in the human genome and Alzheimer’s disease and related dementias. It will leverage large-scale datasets to extensively explore the genome-wide transposable elements and then stratify Alzheimer’s disease-relevant ones by using the rich clinical information from the cohorts. Further analysis pipelines and a predictive model will be built to investigate the functional impact of these transposable elements on Alzheimer’s disease and would improve the understanding of genetic causes of Alzheimer’s disease and related dementias.

Hala Darwish, Ph.D., Associate Professor, School of Nursing, University of Michigan

Andrew Bender, PhD (Michigan State University)

Goal: The maintenance of cognitive abilities in older age despite neural decrements appears to reflect one’s capacity for cognitive and neural plasticity. Such resilience to neuropathological processes appears moderated by educational attainment and life course enrichment, but there are no established markers of resilience. The proposed pilot study seeks to establish feasibility for studying new markers of resilience against early neurocognitive decline in mild cognitive impairment (MCI) by leveraging existing data and resources from the MADRC longitudinal clinical cohort. We propose evaluating the potential of novel markers from existing diffusion MRI neuroimaging and neuropsychological test data to classify early declines in MCI. Specifically, we will investigate novel measures of white matter crossing fiber complexity and cognitive plasticity (i.e., practice effects), as potential markers of neurocognitive resilience against declines in MCI. We will evaluate differences in baseline level and 1–2 year longitudinal change to test whether short-term changes in practice effects and crossing fiber populations are attenuated or absent in MCI. We will examine whether these markers are less biased by race and ethnicity than other neuropsychological measures of cognitive decline. The proposed pilot study will lead to development of a collaborative R01 proposal to investigate new markers of neurocognitive resilience.

DeAnnah Byrd, PhD (Wayne State University)

Goal: Cognitive decline is a substantial and growing public health concern. The older U.S. population is expected to increase dramatically by 2030, growing from 35 to 72 million, and becoming significantly more racially and ethnically diverse. Most concerning are reports suggesting that Blacks have a higher risk of cognitive disease than Whites. In particular, Blacks have more chronic conditions such as high blood pressure (HBP), diabetes, and stroke, which can affect the brain and cognition. Likewise, Blacks are further disproportionately exposed to stress. Although, social support and coping resources have been shown to positively impact health outcomes and buffer against stress; few studies have examined whether health status, stress, and coping factors account for differences in cognitive decline in Blacks. The goal of this project is to explore innovative approaches to address individual variation in risk and protective factors contributing to cognitive changes and decline in Blacks. This project uses secondary data taken from the Baltimore Study of Black Aging—Patterns of Cognitive Aging to examine whether health and psychosocial factors that differ by race (e.g., HBP and perceived stress as risks and social support and coping as protective factors) underlie racial inequalities in cognitive decline in older U.S. adults.

Ana Daugherty, PhD (Wayne State University)

Goal: Hypertension is the most prevalent and pernicious vascular risk factor that exacerbates age-related neural cognitive declines. Adequate antihypertensive treatment does not rescue neurological health or cognitive function, which suggests that hypertension has secondary effects on antecedents of neural cognitive decline. Iron accumulation that drives oxidative stress and subsequent metabolic dysfunction is a plausible mechanism of hypertension effects on cognition, and brain iron via MRI is a promising biomarker of impending decline in aging, Alzheimer’s disease and related dementia (ADRD). Iron preferentially accumulates in age-sensitive brain regions—e.g., striatum, hippocampus—which may be exacerbated by hypertension to explain greater cognitive decline. Brain iron accumulation is a putative biomarker sensitive to early stages of neurodegeneration, yet its interaction with hypertension is unknown. This proposal uses the existing Michigan ADRC sample to evaluate the effect of hypertension and vascular risk on subcortical iron concentration, two-year cognitive decline, and ADRD diagnosis. A subset of the existing sample will be recruited to undergo a state-of-the-art high-resolution hippocampal subfield scan to evaluate the possible correlation between hippocampal iron concentration and entorhinal cortex and subiculum volumes as additional biomarkers of ADRD pathology. The study aims to evaluate pathways for hypertension effects on ADRD and its progression.

Peter Todd, PhD (University of Michigan)

Goal: Studies in diverse model organisms ranging from yeast to mice and across tissue types, including the brain, demonstrate decreases in global protein synthesis with chronological aging. Age-related changes in the abundance of specific components of the translational apparatus, namely initiation and elongation factors as well as specific ribosomal proteins, suggest that an element of this decline in protein synthesis may result from direct alterations in the translational machinery. Intriguingly, nucleolar size (the site of ribosomal biogenesis) also decreases with age. Interventions that enhance longevity, such as Rapamycin treatment, directly impact translation, suggesting that altered translational dynamics in aging are both important and potentially modifiable. The brain is particularly vulnerable to age-associated declines in cellular physiology since it is made up of a finite number of post-mitotic neurons that rely on localized protein synthesis for certain synaptic functions, suggesting that alterations in translation could contribute to problems in the aging brain.

Despite multiple lines of evidence demonstrating global decreases in translation, we know little about the molecular mechanisms underlying this conserved aging phenomenon. This proposal will use recent advances in transcript specific translational profiling and comparative proteomic approaches to define alterations in the global translational landscape with age and following an intervention (Rapamycin treatment) in UMHET3 mice. My central hypothesis is that age-related alterations in the translational machinery abundance directly impact translational dynamics, leading to age-associated decreases in both global and transcript-specific protein synthesis. This proposal will define the aging “translatome” and generate specific testable predictions as to the molecular mechanisms underlying global decreases in protein translation with age as well as the dynamic changes that occur after rapamycin treatment.

Omar Ahmed, PhD (University of Michigan) 

Goal: By understanding the relationship between retrosplenial ion channels, neuronal subtypes, brain rhythms and memory in both healthy and AD-model animals, the significance of this project spans both basic and translational neuroscience. Specifically, we will 1) elucidate the learning and memory correlates of a recently discovered, unique high frequency oscillation (HFO) localized to the retrosplenial cortex and understand how these retrosplenial HFOs are altered in both a rat and a mouse model of AD; 2) construct a detailed circuit connectivity map among major neuronal subtypes of the RSC and deduce the computations each of these subtypes is ideally suited to perform; 3) test the causal role of high Kv1.1 expression in RSC FS cells in impairing memory function. This work is likely to open up a novel line of research and potential therapies focused on the retrosplenial molecular/cellular underpinnings of AD, and is not directly focused on amyloid-β.

Norman Cheng, PhD (Wayne State University) and Scott Counts, PhD (Michigan State University) 

Goal: The goal of this pilot proposal is to establish proof of concept that magnetic properties of cerebral microbleeds and microinfarcts can be biomarkers for incipient dementia. Currently, these MRI micro-objects are known to be strongly associated with vascular cognitive impairment (VCI) and AD, but they also appear in healthy older people at a lower prevalence. From MRI, counting the number of microbleeds and/or microinfarcts is the only reliable method used clinically. However, the number of these putative lesions is subject to imaging parameters and it does not correlate well with the rate of cognitive decline in AD. As micro-objects with hemorrhagic components show magnetic susceptibility effects in MRI, here we propose to quantify the magnetic properties of these micro-objects from MR images of postmortem samples, validate the hemorrhagic components in those micro-objects from histological studies, and calculate the Cox hazard ratio between demented and control samples. We will request a total of 40 postmortem samples from MADC, all of which will be from subjects with vascular problems. Each of the demented and control groups will contain at least 10 samples. The samples among the two groups will be gender balanced and age matched, as well as be blinded to us.

Matthias Truttman, PhD (University of Michigan)

Goal: Alzheimer’s disease (AD) affects millions of patients worldwide. Despite concerted efforts, the precise cascade of molecular events underlying AD onset and progression remains elusive. Recently, we discovered that, along with histone proteins, the molecular chaperone Hsc70 is post-translationally modified by the attachment of an AMP nucleotide, a process called AMPylation. Intriguingly, the human AMPylase, Hype, accumulates in the nuclei of neocortex-derived neurons from AD patients (Fig. 1A), whereas Hype resides in the cytoplasm of control neurons. We hypothesize that nuclear accumulation of Hype alters the Hsc70 and histone AMPylation landscape, thereby affecting chromatin assembly and accessibility in AD. Our proposed research will address the impact of AMPylation on gene regulation in AD development.

Benjamin Combs, PhD (Michigan State University)

Goal: Inhibition of fast axonal transport (FAT) is closely linked to neurodegeneration of synapses and axons as well as pathological modifications of the tau protein observed early in Alzheimer’s diseases and related tauopathies. It is well established that several of these tau forms can disrupt FAT in multiple models of transport. We have previously identified a molecular mechanism by which tau can disrupt anterograde FAT but do not currently know the mechanism by which they can alter retrograde FAT (rFAT). Here, we propose to use the toxic P301L tau to test two of the major mechanistic pathways that tau could disrupt rFAT: alterations to kinase signaling pathways or direct interaction with the dynein motor complex and its regulatory subunits. We will express wild-type and P301L tau in primary rat hippocampal neurons and measure changes to kinases known to regulate rFAT, perform pulldown experiments to identify relevant protein-protein interactions, and characterize specific changes to rFAT that will inform our understanding of this toxic mechanism. Completion of this proposal will further our mechanistic understanding of non-amyloid toxic effects on rFAT and provide the basis for future grant proposals to further elucidate mechanistic details and explore potential therapeutic interventions.

Patrick Pruitt, PhD (Wayne State University)

Goal: Social isolation has been linked to late-life dementia incidence and, as a modifiable risk factor, represents a target for intervention studies to preserve or enhance cognitive function in older adults. The effects of social isolation on brain
function, through which it impacts cognition, have not been determined. Functional connectivity is an early indicator of neurodegeneration, marking it as a valuable measure for intervention trials, for which early identification of risk is
critical.

Here, we propose an investigation of the association between social isolation and functional connectivity of three core networks underlying cognition: default mode (DMN), frontoparietal (FPN), and salience (SN) networks. We hypothesize that social isolation will be associated with disrupted connectivity within the DMN and SN, as well as disrupted DMN/SN between-network connectivity. We further propose an exploratory analysis of associations between social isolation, network connectivity, and cognition.

We plan to test these hypotheses by analyzing resting-state fMRI scans, Lubben social engagement scores, and performance on neuropsychological testing, in 133 non-demented older adults across the pre-dementia cognitive continuum, for whom data has already been collected through the Michigan Alzheimer’s Disease Center.

Sheria Robinson-Lane, PhD (University of Michigan)

Goal: Family caregivers of Black older adults with Alzheimer's disease and/or related dementias (ADRD) have an elevated risk for developing dementia themselves. Stress-related risk factors likely contribute to this risk and may be reduced through targeted interventions that aim to improve overall cardiovascular health and self-management of chronic disease. Although evidence has demonstrated that culture plays an important role in caregiver outcomes, few interventions have been designed to meet the needs of underserved ethnic and racial populations, leaving a critical need for caregiver informed health interventions that promote effective self-management of chronic disease and the use of personally-relevant ways of coping to manage stress. In addition to reducing ADRD-related disability, culturally rooted and strength-based interventions can improve caregiver health, perceived ability to provide care for a person with ADRC (self-efficacy), and increases the likelihood that caregivers will experience benefits from caregiving. The overall objective of the proposed work is to test the feasibility of a descriptive study designed to identify a culturally responsive approach to caregiver support that will promote adaptive coping and optimize health for Black ADRD family caregivers. The proposed pilot work expands an active study by testing the utility of an electronically delivered questionnaire along with the addition of the Montreal Cognitive Assessment (MOCA) and a grip strength measure. It is anticipated that by integrating the additional cognitive assessment and grip strength measures described, and delivering the survey electronically, an exceptional study may be developed that will lead to a highly effective intervention. This work addresses a void in culturally responsive health interventions for Black ADRD family caregivers.

Benjamin Singer, PhD (University of Michigan) 

Goal: Hospitalization is associated with increased risk of incident dementia among older adults, and patients with underlying Alzheimer’s disease (AD) neuropathology are particularly vulnerable to long-lasting cognitive effects of acute illness. Systemic inflammation, especially sepsis, results in long-lasting neuroinflammatory changes to the brain, especially persistent expression of damage-associated molecular pattern signals and activation of innate immunity. Similar pathways are activated in patients and animal models of AD. I hypothesize that AD results in increased vulnerability to systemic inflammation and potentiates the persistent neuroinflammatory response in sepsis survivors, and that delayed inhibition of neuroinflammation will protect sepsis survivors from persistent brain injury. 5xFAD mice, a transgenic model of AD with accelerated -amyloid production, and wild-type controls will be subjected to sepsis or sham operation and treated with an inhibitor of the innate immune response or vehicle control. I expect that 5xFAD sepsis survivor mice will exhibit impairment in contextual fear conditioning, increased pro-inflammatory gene expression and leukocyte recruitment compared to wild-type sepsis survivors, which will be reversed by inhibition of the innate immune response. Understanding mechanisms of vulnerability to systemic insults in AD will lead to targeted treatments that may prevent or arrest cognitive decline after systemic illness

Chandra Sripada, PhD (University of Michigan)

Goal: To uncover multi-model brain functional connectivity/gene markers of shorter conversion time from MCI to AD by constructing advanced Bayesian low-rank models.

Dr. Chandra Sripada is an Associate Professor of Psychiatry and an Associate Professor of Philosophy at the University of Michigan. His research examines agency, attention, and self-control from cross-disciplinary perspectives.

Navid Seraji-Bozorgzad, MD (University of Michigan) and Rohit Marawar, MD (Wayne State University)

Goal: To examine the cortical microstructure as reflected by two novel MRI techniques, Neurite Orientation Dispersion and Density Imaging (NODDI) and Diffusion Kurtosis Imaging (DKI) in a cohort of African American and White patients with early Alzheimer’s disease.

Dr. Seraji-Bozorgzad is an Assistant Professor of Neurology at the University of Michigan. The interaction of body and brain in disease state are of particular interest to him, both in terms of neurological manifestations of systemic disease, and effect of neurological disease on other systems. His research experience is in the field of MR imaging. He is interested in biomarkers of brain injury and repair, as it applies to various degenerative disorders, including Alzheimer’s disease.

Dr. Rohit Marawar is an Assistant Professor of Neurology at Wayne State University. Dr. Marawar’s expertise and training is in the field of epilepsy. Recently, he transitioned his focus into hyperexcitable brain networks in cognitively normal and abnormal elderly – including those with Alzheimer’s disease and related dementias. Dr. Marawar contributed to the development of the Geriatric Epilepsy Clinic at Wayne State University-Detroit Medical Center.

Peter Todd, MD, PhD (University of Michigan)

Goal: To leverage emerging technologies to identify novel repeat associated RNA-binding proteins (RBPs) and then evaluate their roles in two common genetic forms of dementia: C9orf72-associated frontotemporal dementia (C9FTD) and fragile X-associated tremor/ataxia syndrome (FXTAS).

Dr. Peter Todd is the Bucky and Patti Harris Career Development Professor of Neurology and an Associate Professor of Neurology at the University of Michigan. His research explores the molecular mechanisms in neurodegenerative diseases with a particular interest in repeat expansion diseases such as the recently discovered C9ORF72 expansion underlying frontotemporal dementia. Dr. Todd is also a staff neurologist at the Ann Arbor VA Medical Center. He has worked in the field of Fragile X research for almost 20 years.

Laura Zahodne, PhD (University of Michigan)

Goal: To test the overarching hypothesis that racially-patterned social stress (discrimination) partially explains disparities in cognitive health through its effects on inflammation. In addition, this study will test whether associations among race, social stress, inflammation, and cognition differ according to socioeconomic status and quantify effects of examiner-examinee racial discordance on cognitive performance.

Dr. Laura Zahodne is a clinical neuropsychologist and an Assistant Professor of Psychology at the University of Michigan. Her research interests include psychosocial factors in aging and neurodegenerative disease, psychosocial factors and racial/ethnic diversity in cognitive aging, and statistical modeling of symptom trajectories in aging and neurodegenerative disease.

PI: Jessica Damoiseaux, PhD, Assistant Professor in the Institute of Gerontology and the Department of Psychology at Wayne State University

Project Goal: To determine the difference in hippocampal functional and structural connectivity among older adults along the putative preclinical spectrum from healthy to subjective cognitive impairment (SCI) and mild cognitive impairment (MCI), and its association with objective cognitive performance.

PI: Irving Vega, PhD, Associate Professor of Translational Science & Molecular Medicine at Michigan State University and Magdalena Ivanova, PhD, Research Assistant Professor of Neurology and Adjunct Assistant Professor of Biophysics at the University of Michigan

Project Goal: To understand the role of EFhd2 as a putative modulator of tau oligomerization, in a collaborative effort between researchers at Michigan State University and University of Michigan.

PI: Jenna Wiens, PhD, Assistant Professor in Computer Science Engineering (CSE) at the University of Michigan

Project Goal: The development of methods for leveraging University of Michigan Health System and VA Health Administration Electronic Health Record data for novel retrospective analyses of patient trajectories prior to and following a diagnosis with MCI and AD.

PI: Sami Barmada, MD, PhD, Associate Professor of Neurology at the University of Michigan

Project Goal: To determine the importance of TDP43’s RNA binding domains to neurotoxicity, and to define the TDP43 targets that most closely associate with neurodegeneration in frontotemporal dementia models.

This project is funded by the Erb Family Foundation Grant.

Deborah A. Levine, MD, MPH
Assistant Professor of Internal Medicine and Assistant Professor of Neurology

Goal: to develop, test, and disseminate strategies to improve the care and clinical decision-making of older patients with MCI

Outcome: Data from this study was incorporated into an R01 grant application with Dr. Levine as PI which was funded. They are still in the data collection and analysis phase. There are no publications at this time.

Peter K Todd, MD, PhD
Harris Career Development Professor of Neurology

Goal: To identify novel hexanucleotide repeat expansions as a first step in establishing their roles in the biology of dementia

Outcome: They did not identify any novel repeat expansions as a cause of ALS or other disorders.

Publications: He F, Jones JM, Figueroa-Romero C, Zhang D, Feldman EL, Goutman SA, Meisler MH, Callaghan BC, Todd PK. Screening for novel hexanucleotide repeat expansions at ALS- and FTD-associated loci. Neurology Genetics. Volume 2, Issue 3, May 11th 2016, Page 71.

Vikas Kotagal, MD, MS
Assistant Professor of Neurology

Goal: To test the primary hypothesis that scalp cooling facilitates the glymphatic system and enhances clearance of soluble A-beta.

Outcome: Project is currently ongoing. Dr. Kotagal acquired a mentored VA grant this year.

Publications: There are no publications at this time.

Benjamin Hampstead, PhD
Associate Professor of Psychiatry, Neuropsychology Section

Goal: To examine whether tDCS can reduce the severity of SMCs and improve memory test performance in older adults with such complaints.

Outcome: Project is ongoing.

Christensen KR, Combs B, Richards C, Grabinski T, Alhadidy MM, Kanaan NM. Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons. Mol Neurobiol. 2023 Mar 2. doi: 10.1007/s12035-023-03281-3. Epub ahead of print. PMID: 36859689.  PMCID: PMC10122714

Cox CG, Davis MA, Grill JD, Roberts JS. US Adults' Likelihood to Participate in Dementia Prevention Drug Trials: Results from the National Poll on Healthy Aging. J Prev Alzheimers Dis. 2023;10(1):34-40. doi: 10.14283/jpad.2022.86. PMID: 36641608; PMCID: PMC9579667.

Lichtenberg PA, Mandarino J, Fisher L, Tocco M, Moray J, Shipp M. Implementing a Financial Decision-Making Scale in APS Financial Exploitation Investigations: Use of the PARIHS Conceptual Framework. Gerontologist. 2023 Mar 21;63(3):501-510. doi: 10.1093/geront/gnac085. PMID: 35700036; PMCID: PMC9384297.

McMillan M, Gomez N, Hsieh C, Bekier M, Li X, Miguez R, Tank EMH, Barmada SJ. RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia. Mol Cell. 2023 Jan 19;83(2):219-236.e7. doi: 10.1016/j.molcel.2022.12.019. Epub 2023 Jan 11. PMID: 36634675; PMCID: PMC9899051.

Pang Y, Kukull W, Sano M, Albin RL, Shen C, Zhou J, Dodge HH. Predicting Progression from Normal to MCI and from MCI to AD Using Clinical Variables in the National Alzheimer's Coordinating Center Uniform Data Set Version 3: Application of Machine Learning Models and a Probability Calculator. J Prev Alzheimers Dis. 2023;10(2):301-313. doi: 10.14283/jpad.2023.10. PMID: 36946457; PMCID: PMC10033942.

Sandoval-Pistorius SS, Gerson JE, Liggans N, Ryou JH, Oak K, Li X, Negron-Rios KY, Fischer S, Barsh H, Crowley EV, Skinner ME, Sharkey LM, Barmada SJ, Paulson HL. Ubiquilin-2 regulates pathological alpha-synuclein. Scientific reports. 2023 January 6;13(1):293. PubMed PMID: 36609661; PubMed Central PMCID: PMC9823102; DOI: 10.1038/s41598-022-26899-0.

Scalco R, Hamsafar Y, White CL, Schneider JA, Reichard RR, Prokop S, Perrin RJ, Nelson PT, Mooney S, Lieberman AP, Kukull WA, Kofler J, Keene CD, Kapasi A, Irwin DJ, Gutman DA, Flanagan ME, Crary JF, Chan KC, Murray ME, Dugger BN. The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers. J Neuropathol Exp Neurol. 2023 Feb 21;82(3):202-211. doi: 10.1093/jnen/nlac127. PMID: 36692179; PMCID: PMC9941826.

Beck JS, Madaj Z, Cheema CT, Kara B, Bennett DA, Schneider JA, Gordon MN, Ginsberg SD, Mufson EJ, Counts SE. Co-expression Network Analysis of Frontal Cortex during the Progression of Alzheimer's Disease. Cereb Cortex. 2022 Jan 24:bhac001. doi: 10.1093/cercor/bhac001. Epub ahead of print. PMID: 35076713.

Blair EM, Zahuranec DB, Forman J, Reale BK, Langa KM, Giordani B, Fagerlin A, Kollman C, Whitney RT, Levine DA. Physician Diagnosis and Knowledge of Mild Cognitive Impairment. J Alzheimers Dis. 2022;85(1):273-282. doi: 10.3233/JAD-210565. PMID: 34806602. PMCID: PMC8944779

Byrd DR, Jiang Y, Zilioli S, Thorpe RJ, Lichtenberg PA, Whitfield KE. The Interactive Effects of Education and Social Support on Blood Pressure in African Americans. J Gerontol A Biol Sci Med Sci. 2022 Feb 3;77(2):e98-e106. doi: 10.1093/gerona/glab289. Erratum in: J Gerontol A Biol Sci Med Sci. 2022 Mar 08;: PMID: 34612486; PMCID: PMC8824551.

Byrd DR, Jiang Y, Zilioli S, Thorpe RJ, Lichtenberg PA, Whitfield KE. Corrigendum to: The Interactive Effects of Education and Social Support on Blood Pressure in African Americans. J Gerontol A Biol Sci Med Sci. 2022 May 5;77(5):1098. doi: 10.1093/gerona/glac038. Erratum for: J Gerontol A Biol Sci Med Sci. 2022 Feb 3;77(2):e98-e106. PMID: 35259257; PMCID: PMC9071421.

Chua JP, Bedi K, Paulsen MT, Ljungman M, Tank EMH, Kim ES, McBride JP, Colón-Mercado JM, Ward ME, Weisman LS, Barmada SJ. Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons. Curr Biol. 2022 Jun 20;32(12):2581-2595.e6. doi: 10.1016/j.cub.2022.04.053. Epub 2022 May 16. PMID: 35580604; PMCID: PMC9233098.

Chua JP, De Calbiac H, Kabashi E, Barmada SJ. Autophagy and ALS: mechanistic insights and therapeutic implications. Autophagy. 2022 Feb;18(2):254-282. doi: 10.1080/15548627.2021.1926656. Epub 2021 May 31. PMID: 34057020; PMCID: PMC8942428.

Divers R, Robinson A, Miller L, Davis K, Reed C, Calamia M. Examining heterogeneity in depression symptoms and associations with cognition and everyday function in MCI. J Clin Exp Neuropsychol. 2022 Apr;44(3):185-194. doi: 10.1080/13803395.2022.2102154. Epub 2022 Jul 21. PMID: 35862574.

Duren PS, Moray JR, Lichtenberg PA. Empirical Evaluation of the "Caregivers Passage through Dementia" on African American Caregivers. Clinical gerontologist. 2022 February 27:1-10. PubMed PMID: 35220911; DOI: 10.1080/07317115.2022.2041142.

Elzinga SE, Henn R, Murdock BJ, Kim B, Hayes JM, Mendelson F, Webber-Davis I, Teener S, Pacut C, Lentz SI, Feldman EL. cGAS/STING and innate brain inflammation following acute high-fat feeding. Front Immunol. 2022 Sep 29;13:1012594. doi: 10.3389/fimmu.2022.1012594. PMID: 36248795; PMCID: PMC9556783.

François-Moutal L, Scott DD, Ambrose AJ, Zerio CJ, Rodriguez-Sanchez M, Dissanayake K, May DG, Carlson JM, Barbieri E, Moutal A, Roux KJ, Shorter J, Khanna R, Barmada SJ, McGurk L, Khanna M. Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology. Sci Rep. 2022 May 17;12(1):8140. doi: 10.1038/s41598-022-12191-8. PMID: 35581326; PMCID: PMC9114370.

Gerson JE, Sandoval-Pistorius S, Welday JP, Rodriguez A, Gregory JD, Liggans N, Schache K, Li X, Trzeciakiewicz H, Barmada S, Sharkey LM, Paulson HL. Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy. J Neurosci. 2022 Mar 2;42(9):1845-1863. doi: 10.1523/JNEUROSCI.1116-21.2021. Epub 2022 Jan 26. PMID: 35082119; PMCID: PMC8896546.

Hampstead BM, Stringer AY, Iordan AD, Ploutz-Snyder R, Sathian K. Toward rational use of cognitive training in those with mild cognitive impairment. Alzheimers Dement. 2022 Jul 6. doi: 10.1002/alz.12718. Epub ahead of print. PMID: 35791724.

Hall L, Campbell R, Gross E, Lichtenberg PA. The Impact of Financial Coaching on Older Adult Victims of Financial Exploitation: A Quasi-Experimental Research Study. Financ CounPlan. 2022;33(1):66-78. doi: 10.1891/jfcp-20-00047. PMID: 35655948; PMCID: PMC9159538.

Henn RE, Noureldein MH, Elzinga SE, Kim B, Savelieff MG, Feldman EL. Glial-neuron crosstalk in health and disease: A focus on metabolism, obesity, and cognitive impairment. Neurobiol Dis. 2022 Aug;170:105766. doi: 10.1016/j.nbd.2022.105766. Epub 2022 May 16. PMID: 35584728.

Jones LM, Moss KO, Mitchell J, Still C, Hawkins J, Tang E, Wright KD. Challenges to dietary hypertension self-management as described by a sample of African American older adults. Worldviews Evid Based Nurs. 2022 Feb;19(1):64-72. doi: 10.1111/wvn.12555. Epub 2022 Jan 22. PMID: 35064763. PMCID: PMC9590287

Kairys A, Daugherty A, Kavcic V, Shair S, Persad C, Heidebrink J, Bhaumik A, Giordani B. Laptop-Administered NIH Toolbox and Cogstate Brief Battery in Community-Dwelling Black Adults: Unexpected Pattern of Cognitive Performance between MCI and Healthy Controls. J Int Neuropsychol Soc. 2022 Mar;28(3):239-248. doi: 10.1017/S135561772100028X. Epub 2021 Mar 23. PMID: 33752763.

Kara B, Gordon MN, Gifani M, Dorrance AM, Counts SE. Vascular and Nonvascular Mechanisms of Cognitive Impairment and Dementia. Clin Geriatr Med. 2023 Feb;39(1):109-122. doi: 10.1016/j.cger.2022.07.006. Epub 2022 Oct 18. PMID: 36404024.

Kelley CM, Ginsberg SD, Liang WS, Counts SE, Mufson EJ.  Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders. Brain Commun. 2022 Jun 21;4(4):fcac162. doi: 10.1093/braincomms/fcac162. PMID: 35813880; PMCID: PMC9263888.

Khalil B, Chhangani D, Wren MC, Smith CL, Lee JH, Li X, Puttinger C, Tsai CW, Fortin G, Morderer D, Gao J, Liu F, Lim CK, Chen J, Chou CC, Croft CL, Gleixner AM, Donnelly CJ, Golde TE, Petrucelli L, Oskarsson B, Dickson DW, Zhang K, Shorter J, Yoshimura SH, Barmada SJ, Rincon-Limas DE, Rossoll W. Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy. Mol Neurodegener. 2022 Dec 8;17(1):80. doi: 10.1186/s13024-022-00585-1. PMID: 36482422; PMCID: PMC9733332.

Krishnan G, Raitcheva D, Bartlett D, Prudencio M, McKenna-Yasek DM, Douthwright C, Oskarsson BE, Ladha S, King OD, Barmada SJ, Miller TM, Bowser R, Watts JK, Petrucelli L, Brown RH, Kankel MW, Gao FB. Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD. Nat Commun. 2022 May 19;13(1):2799. doi: 10.1038/s41467-022-30387-4. PMID: 35589711; PMCID: PMC9119980.

Lei L, Leggett AN, Maust DT.A national profile of sandwich generation caregivers providing care to both older adults and children. J Am Geriatr Soc. 2023 Mar;71(3):799-809. doi: 10.1111/jgs.18138. Epub 2022 Nov 25. PMID: 36427297; PMCID: PMC10023280.

Levine DA, Galecki AT, Plassman BL, Fagerlin A, Wallner LP, Langa KM, Whitney RT, Nallamothu BK, Morgenstern LB, Reale BK, Blair EM, Giordani B, Welsh-Bohmer KA, Kabeto MU, Zahuranec DB. The Association Between Mild Cognitive Impairment Diagnosis and Patient Treatment Preferences: a Survey of Older Adults. J Gen Intern Med. 2022 Jun;37(8):1925-1934. doi: 10.1007/s11606-021-06839-w. Epub 2021 May 7. PMID: 33963503; PMCID: PMC9198187.

Mohan HM, Trzeciakiewicz H, Pithadia A, Crowley EV, Pacitto R, Safren N, Trotter B, Zhang C, Zhou X, Zhang Y, Basrur V, Paulson HL, Sharkey LM. RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control. Cell Mol Life Sci. 2022 Mar 5;79(3):176. doi: 10.1007/s00018-022-04170-z. PMID: 35247097; PMCID: PMC9376861.

Mozersky J, Roberts JS, Rumbaugh M, Chhatwal J, Wijsman E, Galasko D, Blacker D; AGREED. Spillover: The Approval of New Medications for Alzheimer's Disease Dementia Will Impact Biomarker Disclosure Among Asymptomatic Research Participants. J Alzheimers Dis. 2022;90(3):1035-1043. doi: 10.3233/JAD-220113. PMID: 35404285; PMCID: PMC9794032.

Parker K, Vincent B, Rhee Y, Choi BJ, Robinson-Lane SG, Hamm JM, Klawitter L, Jurivich DA, McGrath R. The estimated prevalence of no reported dementia-related diagnosis in older Americans living with possible dementia by healthcare utilization. Aging Clin Exp Res. 2022 Feb;34(2):359-365. doi: 10.1007/s40520-021-01980-2. Epub 2021 Sep 15. PMID: 34524654; PMCID: PMC8925882.

Piette JD, Roberts JS, Marinec N, Chen J, Yon S, Maly M, Swalwell K, Hampstead B. Providing a Purposeful and Stimulating Volunteer Opportunity for Older Adults With Mild Cognitive Impairment: A Pilot Study. Alzheimer Dis Assoc Disord. 2022 Aug 19:10.1097/WAD.0000000000000528. doi: 10.1097/WAD.0000000000000528. Epub ahead of print. PMID: 35984743; PMCID: PMC9938835.

Rahman-Filipiak A, Sadaghiyani S, Davis K, Bhaumik AK, Paulson HL, Giordani B, Hampstead BM. Validation of the National Alzheimer's Coordinating Center (NACC) Lewy Body Disease Module neuropsychological tests. Alzheimers Dement (Amst). 2022 Feb 9;14(1):e12279. doi: 10.1002/dad2.12279. PMID: 35155734; PMCID: PMC8828993.

Robinson-Lane SG, Leggett AN, Johnson FU, Leonard N, Carmichael AG, Oxford G, Miah T, Wright JJ, Blok AC, Iwashyna TJ, Gonzalez R. Caregiving in the COVID-19 pandemic: Family adaptations following an intensive care unit hospitalisation. J Clin Nurs. 2022 Oct 19:10.1111/jocn.16560. doi: 10.1111/jocn.16560. Epub ahead of print. PMID: 36262026; PMCID: PMC9874809.

Rosen AC, Arias JJ, Ashford JW, Blacker D, Chhatwal JP, Chin NA, Clark L, Denny SS, Goldman JS, Gleason CE, Grill JD, Heidebrink JL, Henderson VW, Lavacot JA, Lingler JH, Menon M, Nosheny RL, Oliveira FF, Parker MW, Rahman-Filipiak A, Revoori A, Rumbaugh MC, Sanchez DL, Schindler SE, Schwarz CG, Toy L, Tyrone J, Walter S, Wang LS, Wijsman EM, Zallen DT, Aggarwal NT; members of AGREEDementia. The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All. J Alzheimers Dis. 2022;90(3):953-962. doi: 10.3233/JAD-220458. PMID: 35938255; PMCID: PMC9901285.

Savelieff MG, Chen KS, Elzinga SE, Feldman EL. Diabetes and dementia: Clinical perspective, innovation, knowledge gaps. J Diabetes Complications. 2022 Nov;36(11):108333. doi: 10.1016/j.jdiacomp.2022.108333. Epub 2022 Oct 5. PMID: 36240668; PMCID: PMC10076101.

Tjandra D, Migrino RQ, Giordani B, Wiens J. Use of blood pressure measurements extracted from the electronic health record in predicting Alzheimer's disease: A retrospective cohort study at two medical centers. Alzheimers Dement. 2022 Apr 16. doi: 10.1002/alz.12676. Epub ahead of print. PMID: 35429343.

Wang R, Chopra N, Nho K, Maloney B, Obukhov AG, Nelson PT, Counts SE, Lahiri DK (2022) Human microRNA miR-20b-5p modulates Alzheimer's disease pathways and neuronal function, and a specific polymorphism close to the MIR20Bgene influences Alzheimer's biomarkers. Mol Psychiatry doi: 10.1038/s41380-021-01351-3.  PMID: 35087196   PMCID: PMC9054681

Albin RL, Kordower JH. Reply to: "Cell Therapy for Huntington's Disease: Learning from Failure". Mov Disord. 2021 Mar;36(3):788-789. doi: 10.1002/mds.28500. PMID: 33749915.

Armstrong MJ, Paulson HL, Maixner SM, Fields JA, Lunde AM, Boeve BF, Manning C, Galvin JE, Taylor AS, Li Z. Protocol for an observational cohort study identifying factors predicting accurately end of life in dementia with Lewy bodies and promoting quality end-of-life experiences: the PACE-DLB study. BMJ Open. 2021 May 26;11(5):e047554. doi: 10.1136/bmjopen-2020-047554. PMID: 34039578; PMCID: PMC8160156.

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Fu M, Bakulski KM, Higgins C, Ware EB. Mendelian Randomization of Dyslipidemia on Cognitive Impairment Among Older Americans. Front Neurol. 2021 Jun 23;12:660212. doi: 10.3389/fneur.2021.660212. PMID: 34248819; PMCID: PMC8260932.

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Kanaan NM, Grabinski T. Neuronal and Glial Distribution of Tau Protein in the Adult Rat and Monkey. Front Mol Neurosci. 2021 Apr 27;14:607303. doi: 10.3389/fnmol.2021.607303. PMID: 33986642; PMCID: PMC8112591.

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Kelly SC, Nelson PT, Counts SE. Pontine Arteriolosclerosis and Locus Coeruleus Oxidative Stress Differentiate Resilience from Mild Cognitive Impairment in a Clinical Pathologic Cohort. J Neuropathol Exp Neurol. 2021 Mar 22;80(4):325-335. doi: 10.1093/jnen/nlab017. PMID: 33709107; PMCID: PMC7985827.

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Liu H, Hsieh N, Zhang Z, Zhang Y, Langa KM. Same-Sex Couples and Cognitive Impairment: Evidence From the Health and Retirement Study. J Gerontol B Psychol Sci Soc Sci. 2021 Aug 13;76(7):1388-1399. doi: 10.1093/geronb/gbaa202. PMID: 33211882; PMCID: PMC8499509.

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McGrath R, Robinson-Lane SG, Clark BC, Suhr JA, Giordani BJ, Vincent BM. Self-Reported Dementia-Related Diagnosis Underestimates the Prevalence of Older Americans Living with Possible Dementia. J Alzheimers Dis. 2021;82(1):373-380. doi: 10.3233/JAD-201212. PMID: 34024819. PMCID: PMC8943904

Moinuddin O, Khandwala NS, Young KZ, Sathrasala SK, Barmada SJ, Albin RL, Besirli CG. Role of Optical Coherence Tomography in Identifying Retinal Biomarkers in Frontotemporal Dementia: A Review. Neurol Clin Pract. 2021 Aug;11(4):e516-e523. doi: 10.1212/CPJ.0000000000001041. PMID: 34484950; PMCID: PMC8382404.

Moniruzzaman M, Kadota A, Akash MS, Pruitt PJ, Miura K, Albin R, Dodge HH. Effects of physical activities on dementia-related biomarkers: A systematic review of randomized controlled trials. Alzheimers Dement (N Y). 2021 Jan 20;6(1):e12109. doi: 10.1002/trc2.12109. PMID: 33521235; PMCID: PMC7816814.

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Nkwata AK, Zhang M, Song X, Giordani B, Ezeamama AE. The Relationship of Race, Psychosocial Stress and Resiliency Indicators to Neurocognitive Impairment among Older Americans Enrolled in the Health and Retirement Survey: A Cross-Sectional Study. Int J Environ Res Public Health. 2021 Feb 2;18(3):1358. doi: 10.3390/ijerph18031358. PMID: 33540911; PMCID: PMC7908633.

Polenick CA, Birditt KS, Turkelson A, Kales HC. Chronic condition discordance and physical activity among midlife and older couples. Health Psychol. 2021 Jan;40(1):11-20. doi: 10.1037/hea0001040. PMID: 33370150.

Pinarbasi ES, Liu EA, Yu Z, Kopyov O, Brown NA, Dayalu P, Lieberman AP. Donor-containing cortical and intraventricular glioneuronal nodules in Huntington's disease brain decades after fetal cell transplantation. Acta Neuropathol. 2021 Jun;141(6):979-981. doi: 10.1007/s00401-021-02292-5. Epub 2021 Mar 8. PMID: 33683397; PMCID: PMC8119370.

Roberts JS, Ferber R, Blacker D, Rumbaugh M, Grill JD; Advisory Group on Risk Evidence Education for Dementia (AGREED). Disclosure of individual research results at federally funded Alzheimer's Disease Research Centers. Alzheimers Dement (N Y). 2021 Oct 14;7(1):e12213. doi: 10.1002/trc2.12213. PMID: 34692986; PMCID: PMC8515553.

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Skariah G, Albin RL. Repeat RNA Toxicity Drives Ribosomal RNA Processing Defects in SCA2. Mov Disord. 2021 Nov;36(11):2464-2467. doi: 10.1002/mds.28795. PMID: 34783387; PMCID: PMC8604384.

Skariah G, Todd PK. Translational control in aging and neurodegeneration. Wiley Interdiscip Rev RNA. 2021 Jul;12(4):e1628. doi: 10.1002/wrna.1628. Epub 2020 Sep 20. PMID: 32954679; PMCID: PMC7979572

Soliman AS, Umstead A, Grabinski T, Kanaan NM, Lee A, Ryan J, Lamp J, Vega IE. EFhd2 brain interactome reveals its association with different cellular and molecular processes. J Neurochem. 2021 Dec;159(6):992-1007. doi: 10.1111/jnc.15517. Epub 2021 Oct 3. PMID: 34543436; PMCID: PMC9552186.

Tipirneni R, Levy HG, Langa KM, McCammon RJ, Zivin K, Luster J, Karmakar M, Ayanian JZ. Changes in Health Care Access and Utilization for Low-SES Adults Aged 51-64 Years After Medicaid Expansion. J Gerontol B Psychol Sci Soc Sci. 2021 Jun 14;76(6):1218-1230. doi: 10.1093/geronb/gbaa123. PMID: 32777052; PMCID: PMC8200354.

Ware EB, Morataya C, Fu M, Bakulski KM. Type 2 Diabetes and Cognitive Status in the Health and Retirement Study: A Mendelian Randomization Approach. Front Genet. 2021 Mar 25;12:634767. doi: 10.3389/fgene.2021.634767. PMID: 33868373; PMCID: PMC8044888.

Zahodne LB. Biopsychosocial pathways in dementia inequalities: Introduction to the Michigan Cognitive Aging Project. Am Psychol. 2021 Dec;76(9):1470-1481. doi: 10.1037/amp0000936. PMID: 35266748; PMCID: PMC9205325.

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Kornblith ES, Yaffe K, Langa KM, Gardner RC. Prevalence of Lifetime History of Traumatic Brain Injury among Older Male Veterans Compared with Civilians: A Nationally Representative Study. J Neurotrauma. 2020 Dec 15;37(24):2680-2685. doi: 10.1089/neu.2020.7062. Epub 2020 Aug 26. PMID: 32762279; PMCID: PMC7869884.

Garcia S, Hampstead BM. HD-tDCS as a neurorehabilitation technique for a case of post-anoxic leukoencephalopathy. Neuropsychol Rehabil. 2020 Nov 18:1-21. doi: 10.1080/09602011.2020.1845749. Epub ahead of print. PMID: 33208043; PMCID: PMC8128934.

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Mitchell J, Perry T, Rorai V, Ilardo J, Lichtenberg PA, Jackson JS. Building and Sustaining a Community Advisory Board of African American Older Adults as the Foundation for Volunteer Research Recruitment and Retention in Health Sciences. Ethn Dis. 2020 Nov 19;30(Suppl 2):755-764. doi: 10.18865/ed.30.S2.755. PMID: 33250622; PMCID: PMC7683030.

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Cerino ES, Hooker K, Goodrich E, Dodge HH. Personality Moderates Intervention Effects on Cognitive Function: A 6-Week Conversation-Based Intervention. Gerontologist. 2020 Jul 15;60(5):958-967. doi: 10.1093/geront/gnz063. PMID: 31112605; PMCID: PMC7362618.

Mahoney S, Bradley A, Pitts L, Waletzko S, Robinson-Lane SG, Fairchild T, Terbizan DJ, McGrath R. Health Insurance Is Associated with Decreased Odds for Undiagnosed Prediabetes and Type 2 Diabetes in American Adults. Int J Environ Res Public Health. 2020 Jun 30;17(13):4706. doi: 10.3390/ijerph17134706. PMID: 32629937; PMCID: PMC7369944.

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Armstrong MJ, Alliance S, Corsentino P, Maixner SM, Paulson HL, Taylor A. Caregiver-Reported Barriers to Quality End-of-Life Care in Dementia With Lewy Bodies: A Qualitative Analysis. Am J Hosp Palliat Care. 2020 Jan 6:1049909119897241. doi: 10.1177/1049909119897241. [Epub ahead of print] PubMed PMID: 31902223.

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Yeh AY, Pressler SJ, Algase D, Struble LM, Pozehl BJ, Berger AM, Giordani BJ. Sleep-Wake Disturbances and Episodic Memory in Older Adults. Biol Res Nurs. 2020 Jul 10:1099800420941601. doi: 10.1177/1099800420941601. Epub ahead of print. PMID: 32648471. PMC Journal – In Process.

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Mezuk B, Tarraf W, Johnson-Lawrence V, Ilardo J, Lichtenberg PA, Jackson JS. Analytic Training for Junior Investigators in Minority Aging Research: The Michigan Model. Gerontologist. 2020 Apr 30:gnaa001. doi: 10.1093/geront/gnaa001. Epub ahead of print. PMID: 32352144. PMC Journal – In Process.

Lichtenberg PA, Campbell R, Hall L, Gross EZ. Context Matters: Financial, Psychological, and Relationship Insecurity Around Personal Finance Is Associated With Financial Exploitation. Gerontologist. 2020 Mar 25:gnaa020. doi: 10.1093/geront/gnaa020. Epub ahead of print. PMID: 32211847. J Alzheimers Dis. PMC Journal – In Process.

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Mackenzie SJ, Lin CC, Todd PK, Burke JF, Callaghan BC. Genetic testing utilization for patients with neurologic disease and the limitations of claims data. Neurology Genetics. 2020 Feb 26;6(2):e405. PMCID: PMC7061285 DOI: 10.1212/NXG.0000000000000405.

He F, Flores BN, Krans A, Frazer M, Natla S, Niraula S, Adefioye O, Barmada SJ, Todd PK. The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD. Acta Neuropathol Commun. 2020 Aug 4;8(1):122. doi: 10.1186/s40478-020-01002-8. PMID: 32753055; PMCID: PMC7401224.

Rodriguez CM, Wright SE, Kearse MG, Haenfler JM, Flores BN, Liu Y, Ifrim MF, Glineburg MR, Krans K, Jafar-Nejad P, Sutton MA, Bassell GJ, Parent JM, Rigo F, Barmada SJ, Todd PK. A native function for RAN translation and CGG repeats in regulating Fragile X protein synthesis. Nat Neuroscience 2020; 23: 386-397, 03/2020. PMID: 32066985  PMC Journal – In Process.

Sweidan W, Bao F, Bozorgzad NS, George E. White and Gray Matter Abnormalities in Manifest Huntington's Disease: Cross-Sectional and Longitudinal Analysis. J Neuroimaging. 2020 May;30(3):351-358. doi: 10.1111/jon.12699. Epub 2020 Mar 3. PMID: 32128927. PMC Journal – In Process.

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Viviano RP, Damoiseaux JS. Functional neuroimaging in subjective cognitive decline: current status and a research path forward. Alzheimers Res Ther. 2020 Mar 9;12(1):23. doi: 10.1186/s13195-020-00591-9. Review. PubMed PMID: 32151277; PubMed Central PMCID: PMC7063727.

Crane NT, Hayes JM, Viviano RP, Bogg T, Damoiseaux JS. Resting-state functional brain connectivity in a predominantly African-American sample of older adults: exploring links among personality traits, cognitive performance, and the default mode network. Personal Neurosci. 2020;3:e3. doi: 10.1017/pen.2020.4. eCollection 2020. PubMed PMID: 32524064; PubMed Central PMCID: PMC7253688.

Li P, Ensink E, Lang S, Marshall L, Schilthuis M, Lamp J, Vega I, Labrie V. Hemispheric asymmetry in the human brain and in Parkinson's disease is linked to divergent epigenetic patterns in neurons. Genome Biol. 2020 Mar 9;21(1):61. doi: 10.1186/s13059-020-01960-1. PMID: 32151270; PMCID: PMC7063821.

Bakulski KM, Seo YA, Hickman RC, Brandt D, Vadari HS, Hu H, KyunPark S. Heavy Metals Exposure and Alzheimer's Disease and Related Dementias. J Alzheimers Dis. 2020 Jul 7. doi: 10.3233/JAD-200282. Epub ahead of print. PMID: 32651318. PMCID: PMC7454042.

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Garcia MA, Ortiz K, Arévalo SP, Diminich ED, Briceño E, Vega IE, Tarraf W. Age of Migration and Cognitive Function Among Older Latinos in the United States. J Alzheimers Dis. 2020 Jul 8. doi: 10.3233/JAD-191296. Epub ahead of print. PMID: 32651313.

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Byrd DR, Gonzales E, Beatty Moody DL, Marshall GL, Zahodne L, Thorpe Jr. RJ, Whitfield KE. Interactive Effects of Chronic Health Conditions and Financial Hardship on Episodic Memory among Older Blacks: Findings from the Health and Retirement Study. Research in Human Development 2020; 17:1,41-56, DOI: 1080/15427609.2020.1746159.

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Daugherty AM, Sutton BP, Hillman CH, Kramer AF, Cohen NJ, Barbey AK. Individual differences in the neurobiology of fluid intelligence predict responsiveness to training: Evidence from a comprehensive cognitive, mindfulness meditation, and aerobic exercise intervention. Trends Neurosci Educ. 2020 Mar;18:100123. doi: 10.1016/j.tine.2019.100123. Epub 2019 Nov 5. PMID: 32085907.

Daugherty AM, Arble EP. Prevalence of mental health symptoms in residential healthcare workers in Michigan during the covid-19 pandemic. Psychiatry Res. 2020 Jun 30;291:113266. doi: 10.1016/j.psychres.2020.113266. Epub ahead of print. PMID: 32623265; PMCID: PMC7324917.

Arble E, Steinert SW, Daugherty AM. The application of the Rorschach inkblot test in the study of neural and cognitive aging. Rorschachania 2020; 41: 1-18. doi: 10.1027/1192-5604/a000120 [Epub 2020 Apr 29].

Tang L, Pruitt PJ, Yu Q, Homayouni R, Daugherty AM, Damoiseaux JS, Ofen N. Differential Functional Connectivity in Anterior and Posterior Hippocampus Supporting the Development of Memory Formation. Front Hum Neurosci. 2020 Jun 5;14:204. doi: 10.3389/fnhum.2020.00204. PMID: 32581749; PMCID: PMC7291774.

Daugherty AM, Schwarb HD, McGarry MDJ, Johnson CL, Cohen NJ. Magnetic Resonance Elastography of Human Hippocampal Subfields: CA3-Dentate Gyrus Viscoelasticity Predicts Relational Memory Accuracy. J Cogn Neurosci. 2020 Sep;32(9):1704-1713. doi: 10.1162/jocn_a_01574. Epub 2020 May 7. PMID: 32379003; PMCID: PMC7577400.

Grasser LR, Burghardt P, Daugherty AM, Amirsadri A, Javanbakht A. Inflammation and Trauma-Related Psychopathology in Syrian and Iraqi Refugees. Behav Sci (Basel). 2020 Apr 7;10(4):75. doi: 10.3390/bs10040075. PMID: 32272662; PMCID: PMC7226275.

Rodrigue KM, Daugherty AM, Foster CM, Kennedy KM. Striatal iron content is linked to reduced fronto-striatal brain function under working memory load. Neuroimage. 2020 Apr 15;210:116544. doi: 10.1016/j.neuroimage.2020.116544. Epub 2020 Jan 20. PMID: 31972284; PMCID: PMC7054151.

Nkwata AK, Song X, Zhang M, Ezeamama AE. Change in quality of life over eight years in a nationally representative sample of US adults with heart disease and type 2 diabetes:minority race and toxic stress as keysocial determinants. BMC Public Health. 2020 May 14;20(1):684. doi: 10.1186/s12889-020-08842-y. PMID: 32410708; PMCID: PMC7222334.

Birditt KS, Polenick CA, Luong G, Charles ST, Fingerman KL. Daily interpersonal tensions and well-being among older adults: The role of emotion regulation strategies. Psychol Aging. 2020 Jun;35(4):578-590. doi: 10.1037/pag0000416. Epub 2019 Oct 31. PMID: 31670541.

Polenick CA, Birditt KS, Turkelson A, Bugajski BC, Kales HC. Discordant Chronic Conditions and Depressive Symptoms: Longitudinal Associations Among Middle-Aged and Older Couples. J Gerontol B Psychol Sci Soc Sci. 2019 Dec 3:gbz137. doi: 10.1093/geronb/gbz137. Epub ahead of print. PMID: 31792532.

Polenick CA, Birditt KS, Turkelson A, Kales HC. Individual-Level and Couple-Level Discordant Chronic Conditions: Longitudinal Links to Functional Disability. Ann Behav Med. 2020 Jun 12;54(7):455-469. doi: 10.1093/abm/kaz061. PMID: 31858110; PMCID: PMC7291341.

Polenick CA, Min L, Kales HC. Medical Comorbidities of Dementia: Links to Caregivers' Emotional Difficulties and Gains. J Am Geriatr Soc. 2020 Mar;68(3):609-613. doi: 10.1111/jgs.16244. Epub 2019 Nov 20. PMID: 31746461; PMCID: PMC7354235.

Birditt KS, Sherman CW, Polenick CA, Becker L, Webster NJ, Ajrouch KJ, Antonucci TC. So Close and Yet So Irritating: Negative Relations and Implications for Well-being by Age and Closeness. J Gerontol B Psychol Sci Soc Sci. 2020 Jan 14;75(2):327-337. doi: 10.1093/geronb/gby038. PMID: 29596623; PMCID: PMC7179808.

Leggett AN, Meyer OL, Bugajski BC, Polenick CA. Accentuate the Positive: The Association Between Informal and Formal Supports and Caregiving Gains. J Appl Gerontol. 2020 Apr 24:733464820914481. doi: 10.1177/ 0733464820914481. Epub ahead of print. PMID: 32326797; PMCID: PMC7584731.

Hampstead BM, Bahar-Fuchs A. Neurophysiological mechanisms and outcomes of nonpharmacologic interventions for neurological disease or injury: Introduction to special issue. Int J Psychophysiol. 2020 Aug;154:1-2. doi: 10.1016/j.ijpsycho.2020.02.010. Epub 2020 Feb 19. PMID: 32115258.

Dong Q, Zhang J, Li Q, Wang J, Leporé N, Thompson PM, Caselli RJ, Ye J, Wang Y; Alzheimer’s Disease Neuroimaging Initiative. Integrating Convolutional Neural Networks and Multi-Task Dictionary Learning for Cognitive Decline Prediction with Longitudinal Images. J Alzheimers Dis. 2020;75(3):971-992. doi: 10.3233/JAD-190973. PMID: 32390615; PMCID: PMC7427104.

Hampstead BM, Ehmann M, Rahman-Filipiak A. Reliable use of silver chloride HD-tDCS electrodes. Brain Stimul. 2020 Jul-Aug;13(4):1005-1007. doi: 10.1016/j.brs.2020.04.003. Epub 2020 Apr 10. PMID: 32278714.

Tolle KA, Rahman-Filipiak AM, Hale AC, Kitchen Andren KA, Spencer RJ. Grooved Pegboard Test as a measure of executive functioning. Appl Neuropsychol Adult. 2020 Sep-Oct;27(5):414-420. doi: 10.1080/23279095.2018.1559165. Epub 2019 Feb 8. PMID: 30734576.

Požar R, Giordani B, Kavcic V. Effective differentiation of mild cognitive impairment by functional brain graph analysis and computerized testing. PLoS One. 2020 Mar 16;15(3):e0230099. doi: 10.1371/journal.pone.0230099. PMID: 32176709; PMCID: PMC7075594.

Simon SS, Hampstead BM, Nucci MP, Ferreira LK, Duran FLS, Fonseca LM, Martin MM, Avila R, Porto FHG, Brucki SMD, Martins CB, Tascone LS, Amaro E, Busatto GF, Bottino CM. Mnemonic strategy training modulates functional connectivity at rest in mild cognitive impairment: results from a randomized controlled trial. Alzheimer's & Dementia: Translational Research & Clinical Interventions. 2020. PMC Journal – PMID: 33204817; PMCID: PMC7647944

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McKay EC, Counts SE. Oxytocin Receptor Signaling in Vascular Function and Stroke. Front Neurosci. 2020 Sep 25;14:574499. doi: 10.3389/fnins.2020.574499. PMID: 33071746; PMCID: PMC7544744.

Campbell KA, Colacino JA, Park SK, Bakulski KM. Cell Types in Environmental Epigenetic Studies: Biological and Epidemiological Frameworks. Curr Environ Health Rep. 2020 Sep;7(3):185-197. doi: 10.1007/s40572-020-00287-0. PMID: 32794033; PMCID: PMC7493967.

Avila, JF, Rentería, MA, Jones, RN, Vonk JMJ, Turney I, Sol K, Seblova D, Arias F, Hill-Jarrett T, Levy S, Meyer O, Racine AM, Tom S, Melrose RJ, Deters K, Medina LD, Carrion CI, Diaz-Santos M, Byrd DR, Chesebro A, Colon J, Igwe KC, Maas B, Brickman AM, Schupf N, Mayeux R, Manly JJ. Education differentially contributes to cognitive reserve across racial/ethnic groups. Alzheimer's Dement. 2020; 1– 11. https://doi.org/10.1002/alz.12176

Costa MDC, Radzwion M, McLoughlin HS, Ashraf NS, Fischer S, Shakkottai VG, Maciel P, Paulson HL, Öz G. In Vivo Molecular Signatures of Cerebellar Pathology in Spinocerebellar Ataxia Type 3. Mov Disord. 2020 Oct;35(10):1774-1786. doi: 10.1002/mds.28140. Epub 2020 Jul 4. PMID: 32621646; PMCID: PMC7572607.

Feldman SJ, Solway E, Kirch M, Malani P, Singer D, Roberts JS. Correlates of Formal Support Service Use among Dementia Caregivers. J Gerontol Soc Work. 2020 Sep 12:1-16. doi: 10.1080/01634372.2020.1816589. Epub ahead of print. PMID: 32921273.

Dodge HH, Goldstein FC, Wakim NI, Gefen T, Teylan M, Chan KCG, Kukull WA, Barnes LL, Giordani B, Hughes TM, Kramer JH, Loewenstein DA, Marson DC, Mungas DM, Mattek N, Sachs BC, Salmon DP, Willis-Parker M, Welsh-Bohmer KA, Wild KV, Morris JC, Weintraub S; National Alzheimer's Coordinating Center (NACC). Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores. Alzheimers Dement (N Y). 2020 Nov 24;6(1):e12103. doi: 10.1002/trc2.12103. PMID: 33283037; PMCID: PMC7683960.

Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, Al-Hajri Z, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Schniederjan M, Cha S, Perry A, Solomon DA. High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Brain Pathol. 2020. May 18; doi: 10.1111/bpa.12747 (2019) PMID: 31104347. PMCID: PMC6859193

Polenick CA, Kim Y, DePasquale N, Birditt KS, Zarit SH, Fingerman KL. Midlife children’s and older mothers’ depressive symptoms: empathic mother-child relationships as a key moderator. Family Relations. July 2020. [Epub ahead of print.]

Polenick CA, Birditt KS, Turkelson A, Perbix EA, Salwi SM, Zarit SH. Daily social interactions and HPA axis activity among midlife and older adults. The Gerontologist. Dec 2020 [E-pub ahead of print.]

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Ware EB, Mitchell CM, Faul JD, Bakulski KM. Nov 2020. Considering the APOE locus in polygenic scores for Alzheimer’s disease in the Health and Retirement Study: A longitudinal panel study. BMC Medical Genomics. PMID: 33143703. PMCID: PMC7607711 

Bakulski KM, Vadari HS, Faul JD, Heeringa SG, Kardia SLR, Langa KM, Smith JA, Manly JJ, Mitchell CM, Benke KS, Ware EB. Cumulative genetic risk and APOE-ε4 are independently associated with dementia status in a multi-ethnic, population-based cohort. Neurology Genetics. doi: https://doi.org/10.1101/2020.02.10.20021667

Umegaki H, Makino T, Uemura K, Shimada H, Cheng XW, Dodge H, Kuzuya M. Falls in community-dwelling prefrail older adults. Health & social care in the community. 2020 January;28(1):110-115. PubMed PMID: 31476096; PubMed Central PMCID: PMC8594949; DOI: 10.1111/hsc.12845

Cheran G, Wu L, Lee S, Manoochehri M, Cines S, Fallon E, Lynch T, Heidebrink J, Paulson H, Goldman J, Huey E, Cosentino S: Cognitive Indicators of Preclinical Behavioral Variant Frontotemporal Dementia in MAPT Carriers. J Int Neuropsychol Soc. 2019 Feb;25(2):184-194. doi: 10.1017/S1355617718001005. PMID: 30458895; PMCID: PMC6374161.

Julian MC, Rabia LA, Desai AA, Arsiwala A, Gerson JE, Paulson HL, Kane RS, Tessier PM. Nature-inspired design and evolution of anti-amyloid antibodies. J Biol Chem. 2019 May 24;294(21):8438-8451. doi: 10.1074/jbc.RA118.004731. PMID: 30918024.

Langbaum JB, Karlawish J, Roberts JS, Wood EM, Bradbury A, High N, Walsh TL, Gordon D, Aggarwal R, Davis P, Stowell C, Trisko L, Langlois CM, Reiman EM, Tariot PN. GeneMatch: A novel recruitment registry to conduct at-home APOE genotyping to enhance referrals to Alzheimer’s prevention studies. Alzheimers Dement. 2019 Apr;15(4):515-524. doi: 10.1016/j.jalz.2018.12.007. PMID: 30772251; PMCID: PMC6461487.

Marino S, Zhou N, Zhao Y, Wang L, Wu Q, Dinov I. HDDA: DataSifter: Statistical Obfuscation of Electronic Health Records and Other Sensitive Datasets. J Stat Comput Simul. 2019;89(2):249-271. doi: 10.1080/00949655.2018.1545228. PMID: 30962669; PMCID: PMC6450541.

Meguro K, Dodge HH. Vascular Mild Cognitive Impairment: Identifying Disease in Community- Dwelling Older Adults, Reducing Risk Factors, and Providing Support. The Osaki-Tajiri and Kurihara Projects. J Alzheimers Dis. 2019 Mar 18. doi: 10.3233/JAD-180899. PMID: 30909215.

Umstead A, Vega IE. Tau13 Antibody Preferentially Immunoprecipitates High Molecular Weight Tau Proteins. J Alzheimers Dis. 2019;68(2):511-516. doi: 10.3233/JAD-181187. PMID: 30814358; PMCID: PMC6516460.

Wang X, Becker K, Levine N, Zhang M, Lieberman AP, Moore DJ, Ma. Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration. Acta Neuropathol Commun. 2019 Mar 14;7(1):41. doi: 10.1186/s40478-019-0696-4. PMID: 30871620; PMCID: PMC6419482.

Albin RL. Complementary motivational roles of nigroaccumbens and nigrostriatal dopaminergic pathways. Movement disorders: official journal of the Movement Disorder Society. 2019 January;34(1):45. PubMed PMID: 30653732; PubMed Central PMCID: PMC6812511; DOI: 10.1002/mds.27504.

Bowman GL, Dodge HH, Guyonnet S, Zhou N, Donohue J, Bichsel A, Schmitt J, Hooper C, Bartfai T, Andrieu S, Vellas B. A blood-based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial. Alzheimer's & dementia (New York, N. Y.). 2019; 5:953-963. PubMed PMID: 31921969; PubMed Central PMCID: PMC6944714; DOI: 10.1016/j.trci.2019.11.004.

Langlois CM, Bradbury A, Wood EM, Roberts JS, Kim SYH, Riviere ME, Liu F, Reiman EM, Tariot PN, Karlawish J, Langbaum JB. Alzheimer's Prevention Initiative Generation Program: Development of an APOE genetic counseling and disclosure process in the context of clinical trials. Alzheimer's & dementia. 2019; 5:705-716. PubMed PMID: 31921963; PubMed Central PMCID: PMC6944715; DOI: 10.1016/j.trci.2019.09.013.

Mattos MK, Sereika SM, Beach SR, Kim H, Klunk WE, Knox M, Nadkarni NK, Parker LS, Roberts JS, Schulz R, Tamres L, Lingler JH. Research Use of Ecological Momentary Assessment for Adverse Event Monitoring Following Amyloid-β Results Disclosure. Journal of Alzheimer's disease: JAD. 2019;71(4):1071-1079. PubMed PMID: 31322563; PubMed Central PMCID: PMC6839594; DOI: 10.3233/JAD-190091.

Mufson EJ, Counts SE, Ginsberg SD, Mahady L, Perez SE, Massa SM, Longo FM, Ikonomovic MD. Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease. Frontiers in neuroscience. 2019; 13:533. PubMed PMID: 31312116; PubMed Central PMCID: PMC6613497; DOI: 10.3389/fnins.2019.00533.

Seraji-Bzorgzad N, Paulson H, Heidebrink J. Neurologic examination in the elderly. Handbook of clinical neurology. 2019;167:73-88. PubMed PMID: 31753158; PubMed Central PMCID: PMC7201860. DOI: 10.1016/B978-0-12-804766-8.00005-4.

Zhang W, Lv J, Li X, Zhu D, Jiang X, Zhang S, Zhao Y, Guo L, Ye J, Hu D, Liu T. Experimental Comparisons of Sparse Dictionary Learning and Independent Component Analysis for Brain Network Inference From fMRI Data. IEEE Trans Biomed Eng. 2019 Jan;66(1):289-299. doi: 10.1109/TBME.2018.2831186. Epub 2018 May 17. PMID: 29993466.

Makkie M, Li X, Quinn S, Lin B, Ye J, Mon G, Liu T. A Distributed Computing Platform for fMRI Big Data Analytics. IEEE Trans Big Data. 2019 Jun;5(2):109-119. doi: 10.1109/TBDATA.2018.2811508. Epub 2018 Mar 6. PMID: 31240237; PMCID: PMC6592627

Vega IE, Umstead A, Kanaan NM. EFhd2 Affects Tau Liquid-Liquid Phase Separation. Frontiers in neuroscience. 2019;13:845. PubMed PMID: 31456657; PubMed Central PMCID: PMC6700279; DOI: 10.3389/fnins.2019.00845.

Wei MY, Kabeto MU, Galecki AT, Langa KM. Physical Functioning Decline and Mortality in Older Adults With Multimorbidity: Joint Modeling of Longitudinal and Survival Data. The journals of gerontology. Series A, Biological sciences and medical sciences. 2019 January 16;74(2):226-232. PubMed PMID: 29529179; PubMed Central PMCID: PMC6599282; DOI: 10.1093/gerona/gly038.

Babulal GM, Quiroz YT, Albensi BC, Arenaza-Urquijo E, Astell AJ, Babiloni C, Bahar-Fuchs A, Bell J, Bowman GL, Brickman AM, Chételat G, Ciro C, Cohen AD, Dilworth-Anderson P, Dodge HH, Dreux S, Edland S, Esbensen A, Evered L, Ewers M, Fargo KN, Fortea J, Gonzalez H, Gustafson DR, Head E, Hendrix JA, Hofer SM, Johnson LA, Jutten R, Kilborn K, Lanctôt KL, Manly JJ, Martins RN, Mielke MM, Morris MC, Murray ME, Oh ES, Parra MA, Rissman RA, Roe CM, Santos OA, Scarmeas N, Schneider LS, Schupf N, Sikkes S, Snyder HM, Sohrabi HR, Stern Y, Strydom A, Tang Y, Terrera GM, Teunissen C, Melo van Lent D, Weinborn M, Wesselman L, Wilcock DM, Zetterberg H, O'Bryant SE. Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need. Alzheimer's & dementia: the journal of the Alzheimer's Association. 2019 February;15(2):292-312. PubMed PMID: 30555031; PubMed Central PMCID: PMC6368893; DOI: 10.1016/j.jalz.2018.09.009.

Levine DA, Galecki AT, Langa KM, Unverzagt FW, Kabeto MU, Giordani B, Cushman M, McClure LA, Safford MM, Wadley VG. Blood Pressure and Cognitive Decline Over 8 Years in Middle-Aged and Older Black and White Americans. Hypertension (Dallas, Tex.: 1979). 2019 February;73(2):310-318. PubMed PMID: 30624986; PubMed Central PMCID: PMC6450556; DOI: 10.1161/HYPERTENSIONAHA.118.12062.

Bowman GL, Silbert LC, Dodge HH, Lahna D, Hagen K, Murchison CF, Howieson D, Kaye J, Quinn JF, Shinto L. Randomized Trial of Marine n-3 Polyunsaturated Fatty Acids for the Prevention of Cerebral Small Vessel Disease and Inflammation in Aging (PUFA Trial): Rationale, Design and Baseline Results. Nutrients. 2019 March 29;11(4). PubMed PMID: 30934894; PubMed Central PMCID: PMC6521224; DOI: 10.3390/nu11040735.

Simon SS, Hampstead BM, Nucci MP, Duran FLS, Fonseca LM, Martin MDGM, Ávila R, Porto FHG, Brucki SMD, Martins CB, Tascone LS, Amaro E Jr, Busatto GF, Bottino CMC. Training gains and transfer effects after mnemonic strategy training in mild cognitive impairment: A fMRI study. International journal of psychophysiology: official journal of the International Organization of Psychophysiology. 2019 March 29. PubMed PMID: 30936043; DOI: 10.1016/j.ijpsycho.2019.03.014.

Zhou Y, Zhao L, Zhou N, Zhao Y, Marino S, Wang T, Sun H, Toga AW, Dinov ID. Predictive Big Data Analytics using the UK Biobank Data. Scientific reports. 2019 April 12;9(1):6012. PubMed PMID: 30979917; PubMed Central PMCID: PMC6461626; DOI: 10.1038/s41598-019-41634-y.

Flores BN, Li X, Malik AM, Martinez J, Beg AA, Barmada SJ. An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration. Cell reports. 2019 April 23;27(4):1133-1150.e8. PubMed PMID: 31018129; PubMed Central PMCID: PMC6499398; DOI: 10.1016/j.celrep.2019.03.093.

McKay EC, Beck JS, Khoo SK, Dykema KJ, Cottingham SL, Winn ME, Paulson HL, Lieberman AP, Counts SE. Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia. Journal of neuropathology and experimental neurology. 2019 May 1;78(5):436-452. PubMed PMID: 30990880; PubMed Central PMCID: PMC6467199; DOI: 10.1093/jnen/nlz023.

Roberts JS. Assessing the Psychological Impact of Genetic Susceptibility Testing. The Hastings Center report. 2019 May;49 Suppl 1:S38-S43. PubMed PMID: 31268575; PubMed Central PMCID: PMC7026861; DOI: 10.1002/hast.1015.

Hampstead BM, Stringer AY, Stilla RF, Sathian K. Mnemonic strategy training increases neocortical activation in healthy older adults and patients with mild cognitive impairment. International journal of psychophysiology: official journal of the International Organization of Psychophysiology. 2019 May 5. PubMed PMID: 31067489; PMCID: PMC7218756.

Avesani P, McPherson B, Hayashi S, Caiafa CF, Henschel R, Garyfallidis E, Kitchell L, Bullock D, Patterson A, Olivetti E, Sporns O, Saykin AJ, Wang L, Dinov I, Hancock D, Caron B, Qian Y, Pestilli F. The open diffusion data derivatives, brain data upcycling via integrated publishing of derivatives and reproducible open cloud services. Scientific data. 2019 May 23;6(1):69. PubMed PMID: 31123325; PubMed Central PMCID: PMC6533280; DOI: 10.1038/s41597-019-0073-y.

Ming C, Viassolo V, Probst-Hensch N, Chappuis PO, Dinov ID, Katapodi MC. Machine learning techniques for personalized breast cancer risk prediction: comparison with the BCRAT and BOADICEA models. Breast cancer research: BCR. 2019 June 20;21(1):75. PubMed PMID: 31221197; PubMed Central PMCID: PMC6585114; DOI: 10.1186/s13058-019-1158-4.

Lichtenberg PA, Hall L, Gross E, Campbell R. Providing Assistance for Older Adult Financial Exploitation Victims: Implications for Clinical Gerontologists. Clinical gerontologist. 2019 July;42(4):435-443. PubMed PMID: 30693849; PubMed Central PMCID: PMC7123962; DOI: 10.1080/07317115.2019.1569190.

Tang M, Gao C, Goutman SA, Kalinin A, Mukherjee B, Guan Y, Dinov ID. Model-Based and Model-Free Techniques for Amyotrophic Lateral Sclerosis Diagnostic Prediction and Patient Clustering. 2019 July;17(3):407-421. PubMed PMID: 30460455; PubMed Central PMCID: PMC6527505; DOI: 10.1007/s12021-018-9406-9.

McGrath R, Robinson-Lane SG, Cook S, Clark BC, Herrmann S, O'Connor ML, Hackney KJ. Handgrip Strength Is Associated with Poorer Cognitive Functioning in Aging Americans. J Alzheimers Dis. 2019;70(4):1187-1196. doi: 10.3233/JAD-190042. PMID: 31322562.

Sullivan KJ, Dodge HH, Hughes TF, Chang CH, Zhu X, Liu A, Ganguli M. Declining Incident Dementia Rates Across Four Population-Based Birth Cohorts. The journals of gerontology. Series A, Biological sciences and medical sciences. 2019 August 16;74(9):1439-1445. PubMed PMID: 30312371; PubMed Central PMCID: PMC6696712; DOI: 10.1093/gerona/gly236.

Jones LM, Wright KD, Jack AI, Friedman JP, Fresco DM, Veinot T, Lu W, Moore SM. The relationships between health information behavior and neural processing in African Americans with prehypertension. Journal of the Association for Information Science and Technology. 2019 September;70(9):968-980. PubMed PMID: 31799335; PubMed Central PMCID: PMC6886119; DOI: 10.1002/asi.24098.

Linsalata AE, He F, Malik AM, Glineburg MR, Green KM, Natla S, Flores BN, Krans A, Archbold HC, Fedak SJ, Barmada SJ, Todd PK. DDX3X and specific initiation factors modulate FMR1 repeat-associated non-AUG-initiated translation. EMBO reports. 2019 September;20(9):e47498. PubMed PMID: 31347257; PubMed Central PMCID: PMC6726903; DOI: 10.15252/embr.201847498.

Leggett A, Connell C, Dubin L, Dunkle R, Langa KM, Maust DT, Roberts JS, Spencer B, Kales HC. Dementia Care Across a Tertiary Care Health System: What Exists Now and What Needs to Change. Journal of the American Medical Directors Association. 2019 October;20(10):1307-1312.e1. PubMed PMID: 31147289; PubMed Central PMCID: PMC6768732; DOI: 10.1016/j.jamda.2019.04.006.

Maust DT, Kim HM, Chiang C, Langa KM, Kales HC. Predicting Risk of Potentially Preventable Hospitalization in Older Adults with Dementia. Journal of the American Geriatrics Society. 2019 October;67(10):2077-2084. PubMed PMID: 31211418; PubMed Central PMCID: PMC6896207; DOI: 10.1111/jgs.16030.

Maust DT, Solway E, Langa KM, Kullgren JT, Kirch M, Singer DC, Malani P. Perception of Dementia Risk and Preventive Actions Among US Adults Aged 50 to 64 Years. JAMA neurology. 2019 November 15. PubMed PMID: 31730178; PubMed Central PMCID: PMC6865327; DOI: 10.1001/jamaneurol.2019.3946.

Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fishman A, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Haley D, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kraft R, Kramer J, Kukull W, Lapid M, Litvan I, Ljubenkov P, Lucente D, Lungu C, Mackenzie I, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez M, Miller B, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Roberson ED, Rogalski-Miller E, Sengdy P, Shaw L, Staffaroni AM, Sutherland M, Syrjanen J, Tartaglia C, Tatton N, Taylor J, Toga A, Trojanowski J, Wang P, Wong B, Wszolek Z, Boeve B, Boxer A, Rosen H. Nonlinear Z-score modeling for improved detection of cognitive abnormality. Alzheimer's & dementia (Amsterdam, Netherlands). 2019 December; 11:797-808. PubMed PMID: 31872042; PubMed Central PMCID: PMC6911910; DOI: 10.1016/j.dadm.2019.08.003.

Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Chen Y, Chen K, Chao MV, Counts SE, Mufson EJ. Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology. Neurobiol Dis. 2019 Dec;132:104540. doi: 10.1016/j.nbd.2019.104540. Epub 2019 Jul 23. PMID: 31349032; PMCID: PMC6834890.

Archbold HC, Jackson KL, Arora A, Weskamp K, Tank EM, Li X, Miguez R, Dayton RD, Tamir S, Klein RL, Barmada SJ. TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia. Sci Rep. 2018 Mar 15;8(1):4606. doi: 10.1038/s41598-018-22858-w. PMID: 29545601; PMCID: PMC5854632.

Campbell RJ, Gross E, Lichtenberg PA. Cross-validation of the screening scale in an adult protective services sample. J Elder Abuse Negl. 2018 Nov;8:1-13. doi: 10.1080/08946566.2018.1531098. PMID: 30406729; PMCID: PMC6424609.

Campbell RC, Lichtenberg PA, Hall LN, Teresi JA, Ocepek-Welikson K. Assessment of financial decision making: an informant scale. J Elder Abuse Negl. 2018 Dec;20:1-14. doi: 10.1080/08946566.2018.1556762. PMID: 30570450; PMCID: PMC6445761.

Campbell R, Lichtenberg P. Cross validation of the Lichtenberg Financial Decision-making Screening Scale in an Adult Protective Services sample. Innovation in Aging. 2018 Nov;2(1):670. doi: 10.1093/geroni/igy023.2496. PMID: 30406729; PMCID: PMC6424609.

Cheran G, Silverman H, Manoochehri M, Goldman J, Lee S, Wu L, Cines S, Fallon E, Kelly BD, Olszewska DA, Heidebrink J, Shair S, Campbell S, Paulson H, Lynch T, Cosentino S, Huey ED. Psychiatric symptoms in preclinical behavioural-variant frontotemporal dementia in MAPT mutation carriers. J Neurol Neurosurg Psychiatry. 2018 May;89(5):449-455. doi: 10.1136/jnnp-2017-317263. PMID: 29353234; PMCID: PMC6317727.

Chopra R, Wasserman AH, Pulst SM, De Zeeuw CI, Shakkottai VG. Protein kinase C activity is a protective modifier of Purkinje neuron degeneration in cerebellar ataxia. Hum Mol Genet. 2018 Apr 15;27(8):1396-1410. doi: 10.1093/hmg/ddy050. PMID: 29432535; PMCID: PMC6251693.

Christensen KD, Uhlmann WR, Roberts JS, Linnenbringer E, Whitehouse PJ, Royal CDM, Obisesan TO, Cupples LA, Butson MB, Fasaye GA, Hiraki S, Chen CA, Siebert U, Cook-Deegan R, Green RC. A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone. Genet Med. 2018 Jan;20(1):132-141. doi: 10.1038/gim.2017.103. PMID: 28726810; PMCID: PMC5897910.

Dinov ID, Palanimalai S, Khare A, Christou N. Randomization‐Based Statistical Inference: A Resampling and Simulation Infrastructure. Teach Stat. 2018 Summer;40(2):64-73. doi: 10.1111/test.12156. PMID: 30270947; PMCID: PMC6155997.

Duda M, Zhang H, Li HD, Wall DP, Burmeister M, Guan Y. Brain-specific functional relationship networks inform autism spectrum disorder gene prediction. Transl Psychiatry. 2018 Mar 6;8(1):56. doi: 10.1038/s41398-018-0098-6. PMID: 29507298; PMCID: PMC5838237.

González HM, Tarraf W, Vásquez P, Sanderlin AH, Rosenberg NI, Davis S, Rodríguez CJ, Gallo LC, Thyagarajan B, Daviglus M, Khambaty T, Cai J, Schneiderman N. Metabolic Syndrome and Neurocognition Among Diverse Middle-Aged and Older Hispanics/Latinos: HCHS/SOL Results. Diabetes Care. 2018 Jul;41(7):1501-1509. doi: 10.2337/dc17-1896. PMID: 29716895; PMCID: PMC6014545.

Goyal D, Tjandra D, Migrino RQ, Giordani B, Syed Z, Wiens J. Characterizing heterogeneity in the progression of Alzheimer’s Disease using longitudinal clinical and neuroimaging biomarkers. Alzheimers Dement (Amst). 2018 Aug 10;10:629-637. doi: 10.1016/j.dadm.2018.06.007. PMID: 30456290; PMCID: PMD6234900.

Green KM, Glineburg MR, Kearse MG, Flores BN, Linsalata AE, Fedak SJ, Goldstrohm AC, Barmada SJ, Todd P. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun. 2017 Dec 8;8(1):2005. doi: 10.1038/s41467-017-02200-0. PMID: 29222490; PMCID: PMC5722904

Guan Y, Roter DL, Erby LH, Wolff JL, Gitlin LN, Roberts JS, Green RC, Christensen KD. Communication predictors of patient and companion satisfaction with Alzheimer’s disease genetic risk disclosure. J Health Commun. 2018;23(8):807-814. doi: 10.1080/10810730.2018.1528319. PMID 30325721; PMCID: PMC6452435.

Hoffman GJ, Ha J, Alexander NB, Langa KM, Tinetti M, Min LC. Underreporting of Fall Injuries of Older Adults: Implications for Wellness Visit Fall Risk Screening. J Am Geriatr Soc. 2018 Jul;66(6):1195-1200. doi: 10.1111/jgs.153 60. PMID: 29665016; PMCID: PMC6105546.

Howanitz J, Carney KO, Lichtenberg PA, Donlan A, Sugarman M, Malek, K. Neurocognitive Engagement Therapy: An Innovative Rehabilitation Approach for those with Cognitive Impairment. Topics in Geriatric Rehabilitation. 2018 Jan/Mar;34(1):36-47. doi: 10.1097/TGR.0000000000000172.

Kalinin AA, Allyn-Feuer A, Ade A, Fon GV, Meixner W, Dilworth D, Husain SS, de Wet JR, Higgins GA, Zheng G, Creekmore A, Wiley JW, Verdone JE, Veltri RW, Pienta KJ, Coffey DS, Athey BD, Dinov ID. 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification. Sci Rep. 2018 Sep 12;8(1):13658. doi: 10.1038/s41598-018-31924-2. PMID: 30209281; PMCID: PMC6135819.

Kalinin AA, Higgins GA, Reamaroon N, Soroushmehr S, Allyn-Feuer A, Dinov ID, Najarian K, Athey BD. Deep learning in pharmacogenomics: from gene regulation to patient stratification. Pharmacogenomics. 2018 May;19(7):629-650. doi: 10.2217/pgs-2018-0008. PMID: 29697304; PMCID: PMC6022084.

Kotagal V, Spino C, Bohnen NI, Koeppe R, Albin RL. Serotonin, β-amyloid, and cognition in Parkinson disease. Ann Neurol. 2018 May;83(5):994-1002. doi:1002/ana.25236. PMID: 29665066; PMCID: PMC6021203.

Levine DA, Wadley VG, Langa KM, Unverzagt FW, Kabeto MU, Giordani B, Howard G, Howard VJ, Cushman M, Judd SE, Galecki AT. Risk Factors for Poststroke Cognitive Decline The REGARDS Study (Reasons for Geographic and Racial Differences in Stroke). Stroke. 2018 Apr;49(4):987-994. doi: 10.1161/STROKEAHA.117.018529. PMID: 29581343; PMCID: PMC6419761.

Lichtenberg PA, Gross E, Ficker LJ. Quantifying Risk of Financial Incapacity and Financial Exploitation in Community-dwelling Older Adults: Utility of a Scoring System for the Lichtenberg Financial Decision-making Rating Scale. Clin Gerontol. 2018 Jun:1-15. doi: 10.1080/07317115.2018.1485812. PMID: 29883276; PMCID: PMC6286690.

Lichtenberg PA, Gross E, Campbell R. A Short Form of the Lichtenberg Financial Decision Rating Scale. Clin Gerontol. 2018 Oct:1-10. doi:10.1080/07317115.2018.1527424. PMID: 30321125; PMCID: PMC6465154

Lichtenberg PA, Ocepek-Welikson K, Ficker LJ, Gross E, Rahman-Filipiak A, Teresi JA. Conceptual and Empirical Approaches to Financial Decision-making by Older Adults: Results from a Financial Decision-making Rating Scale. Clin Gerontol. 2018 Jan-Feb;41(1):42-65. doi: 10.1080/07317115.2017.1367748. PMID: 29077531; PMCID: PMC5766370

Lin M, Gong P, Yang T, Ye J, Albin RL, Dodge HH. Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment. Alzheimer Dis Assoc Disord. 2018 Jan-Mar;32(1):18-27. doi: 10.1097/WAD.0000000000000228. PMID: 29227306; PMCID: PMC5854492.

Lingler JH, Roberts JS, Kim H, Morris J, Hu L, Mattos M, McDade E, Lopez O. Amyloid PET candidates may focus more on benefits than risks of results disclosure. Alzheimers Dement (Amst). 2018 May 30;10:413-420. doi 10.1016/j.dadm.2018.05.003. PMID 30094328; PMCID: PMC6072672.

Malik AM, Miguez RA, Li X, Ho YS, Feldman EL, Barmada SJ. Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization. Elife. 2018 Jul 17;7:e35977. pii: e35977. doi: 10.7554/eLife.35977. PMID: 30015619; PMCID: PMC6050042.

Marino S, Xu J, Zhao Y, Zhou N, Zhou Y, Dinov ID^. Controlled feature selection and compressive big data analytics: Applications to biomedical and health studies. PLoS One. 2018 Aug 30;13(8):e0202674. doi: 10.1371/journal.pone.0202674. PMID: 30161148; PMCID:PMC6116997.

Ornstein KA, Garrido MM, Siu AL, Bollens-Lund E, Langa KM, Kelley AS. Impact of In-Hospital Death on Spending for Bereaved Spouses. Health Serv Res. 2018 Aug;53 Suppl 1:2696-2717. doi: 10.1111/1475-6773.12841. PMID: 29488621; PMCID: PMC6056590.

Park SK, Arslan F, Kanneganti V, Barmada SJ, Purushothaman P, Verma SC, Liebman SW. Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins. Prion. 2018;12(1):16-22. doi: 10.1080/19336896.2017.1423185. PMID: 29308690; PMCID: PMC5871033.

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Peloso GM, van der Lee SJ; International Genomics of Alzheimer's Project (IGAP), Destefano AL, Seshardi S. Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease. Alzheimers Dement (Amst). 2018 Sep 22;10:595-598. doi: 10.1016/j.dadm.2018.08.008. PMID: 30422133; PMCID: PMC6215982.

Petyuk VA, Chang R, Ramirez-Restrepo M, Beckmann ND, Henrion MYR, Piehowski PD, Zhu K, Wang S, Clarke J, Huentelman MJ, Xie F, Andreev V, Engel A, Guettoche T, Navarro L, De Jager P, Schneider JA, Morris CM, McKeith IG, Perry RH, Lovestone S, Woltjer RL, Beach TG, Sue LI, Serrano GE, Lieberman AP, Albin RL, Ferrer I, Mash DC, Hulette CM, Ervin JF, Reiman EM, Hardy JA, Bennett DA, Schadt E, Smith RD, Myers AJ. The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target. Brain. 2018 Sep 1;141(9):2721-2739. doi: 10.1093/brain/awy215. PMID: 30137212;  PMCID: PMC6136080.

Pressler SJ, Giordani B, Titler M, Gradus-Pizlo I, Smith D. Dorsey SG, Gao S, Jung M. Design and rationale of the cognitive intervention to improve memory in heart failure patients study. J Cardiovasc Nurs. 2018 Jul/Aug;33(4):344-355. doi: 10.1097/JCN.0000000000000463. PMID: 29601367; PMCID: PMC5995611.

Rahman-Filipiak AM, Giordani B, Heidebrink J, Bhaumik A, Hampstead BM. Self- and Informant-Reported Memory Complaints: Frequency and Severity in Cognitively Intact Individuals and those with Mild Cognitive Impairment and Neurodegenerative Dementias. J Alzheimers Dis. 2018;65(3):1011-1027. doi: 10.3233/JAD-180083. PMID: 30124444; PMCID: PMC6407613.

Reckow J, Rahman-Filipiak A, Garcia S, Schlaefflin S, Calhoun O, DaSilva AF, Bikson M, Hampstead BM. Tolerability and blinding of 4x1 high-definition transcranial direct current stimulation (HD-tDCS) at two and three milliamps. Brain Stimul. 2018 Sep-Oct;11(5):991-997. doi: 10.1016/j.brs.2018.04.022. PMID: 29784589; PMCID: PMC6512313.

Schoeni RF, Freedman VA, Langa KM. Introduction to a Supplement on Population Level Trends in Dementia: Causes, Disparities, and Projections. J Gerontol B Psychol Sci Soc Sci. 2018 Apr;73(suppl_1):S1-S9. doi: 10.1093/geronb/gby007. PMID:29669106; PMCID: PMC6018954

Sharkey LM, Safren N, Pithadia AS, Gerson JE, Dulchavsky M, Fischer S, Patel R, Lantis G, Ashraf N, Kim JH, Meliki A, Minakawa EN, Barmada S, Ivanova MI, Paulson HL. Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10495-E10504. doi: 10.1073/pnas.1810522115. PMID: 30333186; PMCID: PMC6217421.

Silbert LC, Lahna D, Promjunyakul NO, Boespflug E, Ohya Y, Higashiuesato Y, Dodge HH. Risk Factors Associated with Cortical Thickness and White Matter Hyperintensities in Dementia Free Okinawan Elderly. J Alzheimers Dis. 63(1):365-372. doi: 10.3233/JAD-171153. PMID: 29578488; PMCID: PMC5900560.

Singer BH, Dickson RP, Denstaedt SJ, Newstead MW, Kim K, Falkowski NR, Erb-Downward JR, Schmidt TM, Huffnagle GB, Standiford TJ. Bacterial Dissemination to the Brain in Sepsis. Am J Respir Crit Care Med. 2018 Mar 15;197(6):747-756. doi: 10.1164/rccm.201708-1559OC. PMID: 29232157; PMCID: PMC5855074.

Tank EM, Figueroa-Romero C, Hinder LM, Bedi K, Archbold HC, Li X, Weskamp K, Safren N, Paez-Colasante X, Pacut C, Thumma S, Paulsen MT, Guo K, Hur J, Ljungman M, Feldman EL, Barmada SJ. Abnormal RNA stability in amyotrophic lateral sclerosis. Nat Commun. 2018 Jul 20;9(1):2845. doi: 10.1038/s41467-018-05049-z. PMID: 30030424; PMCID: PMC6054632.

Tarraf W, Criqui MH, Allison MA, Wright CB, Fornage M, Daviglus M, Kaplan RC, Davis S, Conceicao AS, González HM. Ankle brachial index and cognitive function among Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos. Atherosclerosis. 2018 Apr;271:61-9. doi: 10.1016/j.atherosclerosis.2018.02.016. PMID: 29459267; PMCID: PMC6467470.

Tiernan CT, Mufson EJ, Kanaan NM, Counts SE. Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease. J Neuropathol Exp Neurol. 2018 Mar;77(3):246-259. doi:1093/jnen/nlx120. PMID: 29378005; PMCID: PMC6251641.

Tiernan CT, Ginsberg SD, He B, Ward SM, Guillozet-Bongaarts AL, Kanaan NM, Mufson EJ, Counts SE. Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease. Neurobiol Dis. 2018 Sep;117:125-136. doi: 10.1016/j.nbd.2018.05.021. PMID: 29859871; PMCID: PMC6278831.

Uhlmann WR, Roberts JS. Ethical issues in neurogenetics. Handb Clin Neurol. 2018;147:23-36. doi: 10.1016/B978-0-444-63233-3.00003-8. PMID: 29325614; PMCID: PMC5896012.

Vega IE, Umstead A, Wygant CM, Beck JS, Counts SE.  Ezrin Expression is Increased During Disease Progression in a Tauopathy Mouse Model and Alzheimer's Disease. Curr Alzheimer Res. 2018;15(12):1086-1095. doi: 10.2174/1567205015666180813152043. PMID:30101710; PMCID: PMC6522142.

Vega IE, Sutter A, Parks L, Umstead A, Ivanova MI. Tau's Three-Repeat Domain and EFhd2 Co-incubation Leads to Increased Thioflavin Signal. Front Neurosci. 2018 Dec 3;12:879. doi: 10.3389/fnins.2018.00879. PMID:30559642; PMCID: PMC6286997.

Wang Q, Guo L, Thompson PM, Jack CR, Dodge H, Zhan L^, Zhou J; Alzheimer’s Disease Neuroimaging Initiative and National Alzheimer’s Coordinating Center. The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1. J Alzheimers Dis. 2018;64(1):149-169. doi: 10.3233/JAD-171048. PMID: 29865049; PMCID: PMC6272125.

Wang B, Zeng L, Merillat SA, Fischer S, Ochaba J, Thompson LM, Barmada SJ, Scaglione KM, Paulson HL. The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin. Neurobiol Dis. 2018 Jan;109(Pt A):127-136. doi:1016/j.nbd.2017.10.002. PMID: 28986324;  PMCID: PMC5973538.

Weden MM, Shih RA, Kabeto MU, Langa KM. Secular Trends in Dementia and Cognitive Impairment of U.S. Rural and Urban Older Adults. Am J Prev Med. 2018 Feb;54(2):164-172. doi: 10.1016/j.amepre.2017.10.021. PMID: 29246677; PMCID: PMC5783777.

Wei MY, Kabeto MU, Langa KM, Mukamal KJ. Multimorbidity and Physical and Cognitive Function: Performance of a New Multimorbidity-Weighted Index. J Gerontol A Biol Sci Med Sci. 2018 Jan;73(2):225-232. doi: 10.1093/gerona/glx114. PMID: 28605457; PMCID: PMC5861895.

Weintraub S, Besser L, Dodge HH, Teylan M, Ferris S, Goldstein FC, Giordani B, Kramer J, Loewenstein D, Marson D, Mungas D, Salmon D, Welsh-Bohmer K, Zhou XH, Shirk SD, Atri A, Kukull WA, Phelps C, Morris JC. Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord. 2018 Jan;32(1):10-17. doi: 10.1097/WAD.0000000000000223. PMID: 29240561; PMCID: PMC5821520.

Weskamp K, Barmada SJ. TDP43 and RNA instability in amyotrophic lateral sclerosis. Brain Res. 2018 Aug;1693(Pt A):67-74. pii: S0006-8993(18)30023-4. doi: 10.1016/j.brainres.2018.01.015. PMID: 29395044; PMCID: PMC5997512.

Weskamp K, Barmada SJ. RNA Degradation in Neurodegenerative Disease. Adv Neurobiol. 2018;20:103-142. doi: 10.1007/978-3-319-89689-2_5. PMID: 29916018; PMCID: PMC6498147.

Zhang H, Zhu F, Dodge HH, Higgins GA, Omenn GS, Guan Y, Alzheimer's Disease Neuroimaging Initiative. A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer's disease. Gigascience. 2018 Jul;7(7):giy085. doi: 10.1093/gigascience/giy085. PMID: 30010762; PMCID: PMC6054197.

Al-Ramahi I, Giridharan SSP, Chen YC, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer M, Southall N, Weisman LS, Botas J, Marugan JJ. Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein. Elife. 2017 Dec 26;6. pii: e29123. doi: 10.7554/eLife.29123 PMID: 29256861 PMCID: PMC5743427

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Ankuda CK, Harris J, Ornstein K, Levine DA, Langa KM, Kelley AS. Caregiving for Older Adults with Obesity in the United States. J Am Geriatr Soc. 2017 Sep;65(9):1939-1945. doi: 10.1111/jgs.14918 PMID: 28449347 PMCID: PMC5603353

Ankuda CK, Maust DT, Kabeto MU, McCammon RJ, Langa KM, Levine DA. Association Between Spousal Caregiver Well-Being and Care Recipient Healthcare Expenditures. J Am Geriatr Soc. 2017 Oct;65(10):2220-2226. doi: 10.1111/jgs.15039 PMID: 28836269 PMCID: PMC5762126

Anstey KJ, Peters R, Clare L, Lautenschlager NT, Dodge HH, Barnes DE, Shahar S, Brodaty H, Rees G. Joining forces to prevent dementia: The International Research Network On Dementia Prevention (IRNDP). International psychogeriatrics. 2017 November;29(11):1757-1760. PMID: 28899450 PMCID: PMC5873600.

Basal LA, Yan Y, Shen Y, Haacke EM, Mehrmohammadi M, Allen MJ.Oxidation-Responsive, Eu^II/III-Based, Multimodal Contrast Agent for Magnetic Resonance and Photoacoustic Imaging. ACS Omega. 2017 Mar 31, 2(3): 800-805. doi: 10.1021/acsomega.6b00514. PMID: 28393130 PMCID:PMC5377279

Combs B, Kanaan NM. Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies. Am J Pathol. 2017 Jun;187(6):1222-1229. doi: 10.1016/j.ajpath.2017.01.019. Epub 2017 Apr 14. PubMed PMID: 28413156; PubMed Central PMCID: PMC5818634.

Counts SE, Ikonomovic MD, Mercado N, Vega IE, Mufson EJ. Biomarkers for the Early Detection and Progression of Alzheimer's Disease. Neurotherapeutics. 2017 Jan,14(1): 35-53. doi: 10.1007/s13311-016-0481-z. PMID: 27738903 PMCID: PMC5233625

Crosson B, Hampstead BM, Krishnamurthy LC, Krishnamurthy V, McGregor KM, Nocera JR, Roberts S, Rodriguez AM, Tran SM. Advances in Neurocognitive Rehabilitation Research from 1992 to 2017: The Ascension of Neural Plasticity. Neuropsychology. 2017 Aug 31. doi: 10.1037/neu0000396 PMID: 28857600 PMCID: PMC5788715

Dodge HH, Zhu J, Hughes TF, Snitz BE, Chang CH, Jacobsen EP, Ganguli M. Cohort effects in verbal memory function and practice effects: a population-based study.  International Psychogeriatrics. 2017 Jan, 29(1): 137-148. doi: 10.1017/S1041610216001551. PMID: 27725002 PMCID: PMC5177461

Dodge HH, Zhu J, Woltjer R, Nelson PT, Bennett DA, Cairns NJ, Fardo DW, Kaye JA, Erten-Lyons D, Mattek N, Schneider JA, Silbert LC, Xiong C, Yu L, Schmitt FA, Kryscio RJ, Abner EL. Risk of incident clinical diagnosis of AD-type dementia attributable to pathology confirmed vascular disease. Alzheimer's & Dementia. Alzheimer's and Dementia. 2017, 13(6): 613–623. doi: 10.1016/j.jalz.2016.11.003  PMID: 28017827 PMCID: PMC5466467

Davis MA, Guo C, Sol K, Langa KM, Nallamothu BK. Trends and Disparities in the Number of Self-reported Healthy Older Adults in the United States, 2000 to 2014. JAMA internal medicine. 2017 November 1;177(11):1683-1684. doi: 10.1001/jamainternmed.2017.4357 PMID: 28975206 PMCID: PMC5753793

Gardner RC, Langa KM, Yaffe K. Subjective and objective cognitive function among older adults with a history of traumatic brain injury: A population-based cohort study. PLoS Med. 2017 Mar 7, 14(3): e1002246. doi: 10.1371/journal.pmed.1002246. PMID: 28267747 PMCID: PMC5340352

Green KM, Glineburg MR, Kearse MG, Flores BN, Linsalata AE, Fedak SJ, Goldstrohm AC, Barmada SJ, Todd PK. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nature communications. 2017 December 8;8(1):2005. PubMed PMID: 29222490; PubMed Central PMCID: PMC5722904.

Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Che S, Elarova I, Chen Y, Jeanneteau F, Kranz TM, Chao MV, Counts SE, Mufson EJ. Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease. Hippocampus. 2017 Sept 9. doi:10.1002/hipo.22802. doi: 10.1002/hipo.22802 PMID: 28888073 PMCID: PMC5844851

Grill JD, Apostolova LG, Bullain S, Burns JM, Cox CG, Dick M, Hartley D, Kawas C, Kremen S, Lingler J, Lopez OL, Mapstone M, Pierce A, Rabinovici G, Roberts JS, Sajjadi SA, Teng E, Karlawish J.Communicating mild cognitive impairment diagnoses with and without amyloid imaging. Alzheimers Res Ther. 2017 May 4;9(1):35. doi: 10.1186/s13195-017-0261-y PMID: 28472970 PMCID: PMC5418690

Guan Y, Roter DL, Wolff JL, Gitlin LN, Christensen KD, Roberts JS, Green RC, Erby LH. The impact of genetic counselors’ use of facilitative strategies on cognitive and emotional processing of genetic risk disclosure for Alzheimer’s disease. Patient education and counseling. 2017 Nov 27. doi: 10.1016/j.pec.2017.11.019 PMID: 29203084 PMCID: PMC5911203

Gupta R, Lan M, Mojsilovic-Petrovic J, Choi WH, Safren N, Barmada S, Lee MJ, Kalb R.The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the Proteasome. eNeuro. 2017 Jan 31, 4(1). pii: ENEURO.0249-16.2017. doi: 10.1523/ENEURO.0249-16.2017. PMID: 28197542 PMCID: PMC5282547

Hampstead BM, Sathian K, Bikson M, Stringer AY. Combined Mnemonic Strategy Training and High-Definition Transcranial Direct Current Stimulation for Memory Deficits in Mild Cognitive Impairment Alzheimer's & Dementia. Translational Research & Clinical Interventions. 2017, 3(3): 459-470. doi: 10.1016/j.trci.2017.04.008 PMID: 29067352 PMCID: PMC5651427

Hampstead BM, Towler S, Sathian K, Stringer AY. Continuous measurement of object location memory is sensitive to effects of age and mild cognitive impairment and related to medial temporal lobe volume. Alzheimer's & Dementia: Diagnosis, Assessment and Disease Monitoring. 2017. doi: 10.1016/j.dadm.2017.10.007 PMID: 29255787 PMCID: PMC5724745

Huang Z, Zhang H, Boss J, Goutman SA, Mukherjee B, Dinov ID, Guan Y; Pooled Resource Open-Access ALS Clinical Trials Consortium. Complete hazard ranking to analyze right-censored data: An ALS survival study. PLoS Comput Biol. 2017 Dec 18;13(12):e1005887. doi: 10.1371/journal.pcbi.1005887 PMID: 29253881 PMCID: PMC5749893

Kalinin AA, Palanimalai S, Dinov ID. SOCRAT Platform Design: A Web Architecture for Interactive Visual Analytics Applications. Proceedings of the 2nd Workshop on Human-In-the-Loop Data Analytics. Workshop on Human-In-the-Loop Data Analytics (2nd : 2017 : Chicago, Ill.). 2017 April;2017. PMID: 29630069 PMCID: PMC5884130

Kelly SC, He B, Perez SE, Ginsberg SD, Mufson EJ, Counts SE. Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease. Acta Neuropathological Communications. 2017 Jan 21, 5(1): 8. doi: 10.1186/s40478-017-0411-2. PMID: 28109312 PMCID: PMC5251221

Langa KM, Larson EB, Crimmins EM, Faul JD, Levine DA, Kabeto MU, Weir DR. A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012. JAMA Internal Medicine. 2017 Jan 1,177(1): 51-58. doi: 10.1001/jamainternmed.2016.6807. PMID: 27893041 PMCID: PMC5195883

Larson EB, Langa KM. What's the "Take Home" from Research on Dementia Trends? PLoS Med. 2017 Mar 7, 14(3): e1002236. doi: 10.1371/journal.pmed.1002236. PMID: 28267775 PMCID: PMC5340344

Lichtenberg PA, Ocepek-Welikson K, Ficker LJ, Gross E, Rahman-Filipiak A, Teresi JA. Conceptual and empirical approaches to financial decision-making by older adults: Results from a financial decision-making rating scale. Clinical gerontologist. 2018 Jan 1;41(1):42-65. doi: 10.1080/07317115.2017.1367748 PMID: 29077531 PMCID: PMC5766370

Lichtenberg P, Teresi JA, Ocepek-Welikson K, JosEimicke JP. Reliability and Validity of the Lichtenberg Financial Decision Screening Scale. Innovation in Aging. 2017 Mar 1, 00(00): 1–9.  doi:  10.1093/geroni/igx003. PMID: 29034335  PMCID:  PMC5637552

Lin M, Gong P, Yang T, Ye J , Albin RL, Dodge HH. Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment. Alzheimer's Disease and Associated Disorders. 2017. doi: 10.1097/WAD.0000000000000228 PMID: 29227306 PMCID: PMC5854492

Lindauer A, Seelye A, Lyons B, Dodge HH, Mattek N, Mincks K, Kaye J, Erten-Lyons D. Dementia Care Comes Home: Patient and Caregiver Assessment via Telemedicine. Gerontologist. 2017 Oct 1, 57(5): e85-e93. doi: 10.1093/geront/gnw206.  PMID: 28158415  PMCID: PMC5654345

Luo L, Wang J, Lo RY, Figueroa KP, Pulst SM, Kuo PH, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. The Initial Symptom and Motor Progression in Spinocerebellar Ataxias. Cerebellum (London, England). 2017 June;16(3):615-622. doi: 10.1007/s12311-016-0836-3 PMID: 27848087 PMCID: PMC5429172

Ma X, Bai Y, Lin Y, Hong X, Liu T, Ma L, Haacke EM, Zhou J, Wang J, Wang M. Amide proton transfer magnetic resonance imaging in detecting intracranial hemorrhage at different stages: a comparative study with susceptibility weighted imaging.  Scientific Reports. 2017 Apr 4, 7: 45696. doi: 10.1038/srep45696. PMID: 28374764 PMCID: PMC5379544

Maust DT, Langa KM, Blow FC, Kales HC. Psychotropic use and associated neuropsychiatric symptoms among patients with dementia in the USA. International Journal of Geriatric Psychiatry. 2017 Feb, 32(2): 164-174. doi: 10.1002/gps.4452. PMID: 26889640 PMCID: PMC4990518

McEvoy CT, Guyer H, Langa KM, Yaffe K. Neuroprotective Diets Are Associated with Better Cognitive Function: The Health and Retirement Study. Journal of the American Geriatrics Society. 2017 August;65(8):1857-1862. doi: 10.1111/jgs.14922 PMID: 28440854 PMCID: PMC5633651

McKay E and Counts SE. Multi-infarct dementia: a historical perspective. Dementia and Geriatric Cognitive Disorders Extra. 2017 Jan-Apr, 7(1): 160 - 171. doi: 10.1159/000470836. PMID: 28626470 PMCID: PMC5471781

Ostergren JE, Heeringa SG, Mendes de Leon CF, Connell CM, Roberts JS. The influence of psychosocial and cognitive factors on perceived threat of Alzheimer’s disease. American Journal of Alzheimer’s Disease & Other Dementias. 2017. 32(5), 289-99. doi: 10.1177/1533317517714552. PMID: 28605999 PMCID: PMC5886712

Park SK, Hong JY, Arslan F, Kanneganti V, Patel B, Tietsort A, Tank EMH, Li X, Barmada SJ, Liebman SW. Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis. PLoS genetics. 2017 May;13(5):e1006805. doi: 10.1371/journal.pgen.1006805 PMID: 28531192 PMCID: PMC5460882

Poey JL, Burr JA, Roberts JS. Social connectedness, perceived isolation, and dementia: Does the social environment moderate the relationship between genetic risk and cognitive well-being? The Gerontologist. 2017. 57(6), 1031-40. doi: 10.1093/geront/gnw154. PMID: 28329797

Pressler SJ, Harrison JM, Titler M, Koelling TM, Jung M, Dorsey SG, Bakoyannis G, Riley PL, Hoyland-Domenico L, Giordani B. APOE ε4 and Memory among Patients with Heart Failure.  Western Journal of Nursing Research. 2017, 39(4): 455-472. doi: 10.1177/0193945916670145 PMID: 27733670

Qian J, Wolters FJ, Beiser A, Haan M, Ikram MA, Karlawish J, Langbaum JB, Neuhaus JM, Reiman EM, Roberts JS, Seshadri S, Tariot PN, Woods BM, Betensky RA, Blacker D. APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts. PLoS Med. 2017 Mar 21, 14(3): e1002254. doi: 10.1371/journal.pmed.1002254. PMID: 28323826  PMCID: PMC5360223

Ryan KA, Hammers D, DeLeon A, Bilen H, Frey K, Burke J, Albin R, Barbas N, Heidebrink J, Giordani B. Agreement among neuropsychological and behavioral data and PiB findings in diagnosing Frontotemporal Dementia. Journal of Clinical Neuroscience. 2017 Jun 7. pii: S0967-5868(17)30253-9. doi: 10.1016/j.jocn.2017.05.008. PMCID: PMC5581998  PMID: 28601570

Song W, Woon FL, Doong A, Persad C, Tijerina L, Pandit P, Cline C, Giordani B.  Fatigue in Younger and Older Drivers:  Effectiveness of an Alertness Maintaining Task.  Human Factors. 2017 Sept, 59(6): 995–1008. doi: 10.1177/0018720817706811 PMID: 28510495

Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, D'Amico D, Moullan N, Potenza F, Schmid AW, Rietsch S, Counts SE, Auwerx J. Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity. Nature. 2017 December 14;552(7684):187-193. doi: 10.1038/nature25143 PMID: 29211722 PMCID: PMC5730497

Stelmokas J, Yassay L, Giordani B, Dodge HH, Dinov ID, Bhaumik A, Sathian K, Hampstead BM. Translational MRI Volumetry with NeuroQuant: Effects of Version and Normative Data on Relationships with Memory Performance in Healthy Older Adults and Patients with Mild Cognitive Impairment. Journal of Alzheimer's Disease. 2017, 60; 1499-1510. doi: 10.3233/JAD-170306 PMID: 29060939 PMCID: PMC5858697

Tarraf W, Rodríguez CJ, Daviglus ML, Lamar M, Schneiderman N, Gallo L, Talavera GA, Kaplan RC, Fornage M, Conceicao A, González HM. Blood Pressure and Hispanic/Latino Cognitive Function: Hispanic Community Health Study/Study of Latinos Results. Journal of Alzheimer's disease : JAD. 2017;59(1):31-42. doi: 10.3233/JAD-170017 PMID: 28582859 PMCID: PMC5567691

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Vega IE, Cabrera LY, Wygant CM, Velez-Ortiz D, Counts SE. Alzheimer's Disease in the Latino Community: Intersection of Genetics and Social Determinants of Health. J Alzheimers Dis. 2017. 58(4):979-992. doi: 10.3233/JAD-161261 PMID: 28527211 PMCID: PMC5874398.

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Kavcic V, Zalar B, Giordani B. The relationship between baseline EEG spectra power and memory performance in older African Americans endorsing cognitive concerns in a community setting. International Journal of Psychophysiology. 2016, 109: 116-123. doi:  10.1016/j.ijpsycho.2016.09.001 PMID: 27613569

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Zhang J, Shi J, Stonnington C, Li Q, Gutman BA, Chen K, Reiman EM, Caselli RJ, Thompson PM, Ye J, Wang Y. Hyperbolic Space Sparse Coding with Its Application on Prediction of Alzheimer's Disease in Mild Cognitive Impairment.  Medical Image Comput Comput Assist Interv. 2016 Oct, 9900: 326-334. doi: 10.1007/978-3-319-46720-7_38 PMID: 28066843 PMCID: PMC5217478

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Reams N, Eckner JT, Almeida AA, Aagesen AL, Giordani B, Paulson H, Lorincz MT, Kutcher JS. A clinical approach to the diagnosis of traumatic encephalopathy syndrome: A review.  Journal of the American Medical Association: Neurology. 2016, 73(6): 734-749. doi: 10.1001/jamaneurol.2015.5015 PMID: 27111824 PMCID: PMC4922002

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Gabel NM, Crane NA, Avery ET, Kay RE, Laurent A, Giordani B, Alexander NB, Weisenbach SL. Dual-tasking gait variability and cognition in late-life depression. Int J Geriatr Psychiatry. 2015 Nov, 30(11): 1120-8. doi: 10.1002/gps.4340 PMID: 26251013

Albin RL, Fisher-Hubbard A, Shanmugasundaram K, Koeppe RA, Burke JF, Camelo-Piragua S, Lieberman AP, Giordani B, Frey KA. Post-mortem evaluation of amyloid-dopamine terminal positron emission tomography dementia classifications. Ann Neurol. 2015 Nov, 78(5): 824-30. doi: 10.1002/ana.24481. PMID: 26183692 PMCID: PMC4836870

Mufson EJ, Mahady L, Waters D, Counts SE, Perez SE, DeKosky ST, Ginsberg SD, Ikonomovic MD, Scheff SW, Binder L. Hippocampal plasticity during the progression of Alzheimer’s disease. Neuroscience. 2015 Nov 19, 309: 51-67. doi: 10.1016/j.neuroscience.2015.03.006. PMID: 25772787 PMCID: PMC4567973

Sachdev PS, Lipnicki DM, Kochan NA, Crawford JD, Thalamuthu A, Andrews G, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Carrière I, Ancelin ML, Lam LC, Wong CH, Fung AW, Guaita A, Vaccaro R, Davin A, Ganguli M, Dodge HH, Hughes T, Anstey KJ, Cherbuin N, Butterworth P, Ng TP, Gao Q, Reppermund S, Brodaty H, Schupf N, Manly J, Stern Y, Lobo A, Lopez-Anton R, Santabárbara J. The prevalence of mild cognitive impairment in diverse geographical and ethnocultural regions: the COSMIC collaboration. PLoS One. 2015 Nov 5, 10(11): e0142388. doi: 10.1371/journal.pone.0142388 PMID: 26539987 PMCID:PMC4634954

Friedman EM, Shih RA, Langa KM, Hurd MD.US prevalence and predictors of informal caregiving for dementia. Health Aff (Millwood). 2015 Oct, 34(10): 1637-41. doi: 10.1377/hlthaff.2015.0510 PMID: 26438738 PMCID: PMC4872631

Beach PA, Huck JT, Miranda MM, Bozoki AC. Autonomic, behavioral, and subjective pain responses in Alzheimer’s disease. Pain Med. 2015 Oct;16(10):1930-42. doi: 10.1111/pme.12769 PMID: 25929320

Beach PA, Huck JT, Miranda MM, Bozoki AC. Factors associated with cognitive evaluations in the United States. Pain Med. 2015 Oct, 16(10): 1930-42. doi: 10.1111/pme.12769 PMID: 25929320 PMCID: PMC4336093

Lichtenberg PA, Ficker LJ, Rahman-Filipiak A. Financial decision-making abilities and exploitation in older African Americans: Preliminary validity evidence for the Lichtenberg Financial Decision Rating Scale (LFDRS). J Elder Abuse Negl. 2016, 28(1): 14-33. doi: 10.1080/08946566.2015.1078760 PMID: 26285038 PMCID: PMC4740256

Oh SY, He F, Krans A, Frazer M, Taylor JP, Paulson HL, Todd PK. RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome. Hum Mol Genet. 2015 Aug 1, 24(15): 4317-26. doi: 10.1093/hmg/ddv165 PMID: 25954027 PMCID: PMC4492395

Votruba KL, Persad C, Giordani B. Patient mood and instrumental activities of daily living in Alzheimer disease: Relationship between patient and caregiver reports. J Geriatr Psychiatry Neurol. 2015 Sep, 28(3): 203-9. doi: 10.1177/0891988715588829 PMID: 26071443

Levine DA, Galecki AT, Langa KM, Unverzagt FW, Kabeto MU, Giordani B, Wadley VG. Trajectory of cognitive decline after incident stroke. JAMA. 2015 Jul 7, 314(1): 41-51. doi: 10.1001/jama.2015.6968 PMID: 26151265 PMCID: PMC4655087

Kotagal V, Bohnen NI, Müller ML, Koeppe RA, Frey KA, Langa KM, Albin RL. Educational attainment and motor burden in Parkinson’s disease. Mov Disord. 2015 Jul, 30(8): 1143-7. doi: 10.1002/mds.26272 PMID: 26096339 PMCID: PMC4504749

Barmada SJ, Ju S, Arjun A, Batarse A, Archbold HC, Peisach D, Li X, Zhang Y, Tank EM, Qiu H, Huang EJ, Ringe D, Petsko GA, Finkbeiner S. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1. Proc Natl Acad Sci U S A. 2015 Jun 23, 112(25): 7821-6. doi: 10.1073/pnas.1509744112 PMID:26056265 PMCID: PMC4485101

Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE; Alzheimer’s Disease Genetics Consortium; GERAD1 Consortium; EPIC-InterAct Consortium, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA. Associations between potentially modifiable risk factors and Alzheimer disease: A Mendelian Randomization Study. PLoS Med. 2015 Jun 16, 12(6): e1001841; discussion e1001841. doi: 10.1371/journal.pmed.1001841 PMID: 26079503 PMCID: PMC4469461

Fyock CA, Hampstead BM. Comparing the relationship between subjective memory complaints, objective memory performance, and medial temporal lobe volumes in patients with mild cognitive impairment. Alzheimers Dement (Amst). 2015 Jun 1, 1(2): 242-248. doi: 10.1016/j.dadm.2015.03.002 PMID: 26191540 PMCID:PMC4501028

Monsell SE, Dodge HH, Zhou XH, Bu Y, Besser LM, Mock C, Hawes SE, Kukull WA, Weintraub S; Neuropsychology Work Group Advisory to the Clinical Task Force. Results from the NACC Uniform Data Set Neuropsychological Battery Crosswalk Study. Alzheimer Dis Assoc Disord. 2016 Apr-Jun, 30(2): 134-9. doi: 10.1097/WAD.0000000000000111 PMID: 26485498 PMCID: PMC4834278

Atkin G, Moore S, Lu Y, Nelson RF, Tipper N, Rajpal G, Hunt J, Tennant W, Hell JW, Murphy GG, Paulson H. Loss of F-box only protein 2 (Fbxo2) disrupts levels and localization of select NMDA receptor subunits, and promotes aberrant synaptic connectivity. J Neurosci. 2015 Apr 15, 35(15): 6165-78. doi: 10.1523/JNEUROSCI.3013-14.2015 PMID: 25878288 PMCID: PMC4397610

Langa KM. Is the risk of Alzheimer’s disease and dementia declining? Alzheimers Res Ther. 2015 Mar 26, 7(1): 34. doi: 10.1186/s13195-015-0118-1 PMID: 25815064 PMCID: PMC4374373

Moon SW, Dinov ID, Kim J, Zamanyan A, Hobel S, Thompson PM, Toga AW. Structural neuroimaging genetics interactions in Alzheimer’s Disease. J Alzheimers Dis. 2015, 48(4): 1051-63. doi: 10.3233/JAD-150335 PMID: 26444770 PMCID: PMC4730943

Beck JS, Mufson EJ, Counts SE. Evidence for mitochondrial UPR gene activation in familial and sporadic Alzheimer’s disease. Curr Alzheimer Res. 2016, 13(6): 610-4. PMID: 26687188

Moon SW, Dinov ID, Zamanyan A, Shi R, Genco A, Hobel S, Thompson PM, Toga AW; Alzheimer's Disease Neuroimaging Initiative (ADNI). Gene interactions and structural brain change in early-onset Alzheimer’s disease subjects using the pipeline environment. Psychiatry Investig. 2015 Jan, 12(1): 125-35. doi: 10.4306/pi.2015.12.1.125 PMID: 25670955 PMCID: PMC4310910

Hampstead BM, Khoshnoodi M, Yan W, Deshpande G, Sathian K.Patterns of effective connectivity during memory encoding and retrieval differ between patients with mild cognitive impairment and healthy older adults. Neuroimage. 2016 Jan 1, 124(Pt A): 997-1008. doi: 10.1016/j.neuroimage.2015.10.002 PMID: 26458520

Paulson D, Lichtenberg PA. The Paulson-Lichtenberg Frailty Index: evidence for a self-report measure of frailty. Aging Ment Health. 2015, 19(10): 892-901. doi: 10.1080/13607863.2014.986645 PMID: 25537004 PMCID: PMC4480217