January 19, 2022


Core Resources

To download a PDF of this list, please click here.

Clinical Core

Leads: Benjamin Hampstead, Ph.D., ABPP/CN, bhampstea@med.umich.edu and Judith Heidebrink, M.D., M.S., jheide@med.umich.edu

Manager: Stephen Campbell, LLMSW, stepcamp@med.umich.edu


ADRC UDS data and Neuropsychological assessment data. ADRC subject pool.

Biomarker Core

Leads: Dave Morgan, Ph.D., scientist.dave@gmail.com, Nicholas Kanaan, Ph.D., nkanaan@msu.edu


Blood (or other biological fluid) biomarker assessments via SIMOA immunoassays and/or mass spectrometry

Data Management and Statistical Core

Lead: Kelly Bakulski, Ph.D., bakulski@umich.edu

Manager: Jonathan Reader, M.S., readerj@med.umich.edu


Contact information for study recruitment, data for secondary analyses, database design/automation, statistical consultation for grant/manuscript, collaboration for analyses for grant/manuscript

Neuroimaging Core

Lead: Doug Noll, Ph.D., dnoll@umich.edu


Access to neuroimaging data for Michigan ADRC cohorts, consulting on design of imaging components and imaging biomarkers, consulting on image analysis

Neuropathology Core

Lead: Andrew Lieberman, M.D., Ph.D., liebermn@med.umich.edu

Manager: Matthew Perkins, B.A., perkmd@med.umich.edu



Fresh frozen and FFPE (on Slides) post-mortem human samples of various Neurodegenerative diseases. MRotary Microtome of FFPE Tissues, Brain Extraction, and Spinal Cord Extraction (laminectomy), Blood Sample Processing (Buffy coat, Serum, Plasma, Packed Red Blood Cells).

We can also procure desired tissues from donors with neurodegenerative disease through our autopsy services.

Outreach, Recruitment and Engagement Core

Lead: Scott Roberts, Ph.D., jscottr@umich.edu

Manager: Renee Gadwa, M.B.A., rgadwa@med.umich.edu


We can help assist studies actively trying to recruit participants; we can offer speaking opportunities / feature articles on our website/newsletter to promote visibility of their work. We also have a research registry available to junior investigators conducting research studies and we can also share information about research studies through our Center newsletters, social media, and email communications. We host an annual Research Symposium and encourage junior investigators to attend and participate in the poster session/oral presentations. We offer various educational materials about dementia, brain health, and helpful resources for patients and families. We encourage junior investigators to follow and interact with our Center/Center Director Twitter accounts @umichalzheimers and @Henrypaulson5. We are always looking for new faculty to join our group of expert presenters and have speaking opportunities available ongoing. Anyone interested can contact Erin Fox at eefox@med.umich.edu.

Research Education Component

Leads: Roger Albin, M.D., ralbin@med.umich.edu, Peter Lichtenberg, Ph.D., p.lichtenberg@wayne.edu, Irving Vega, Ph.D., vegaie@msu.edu

Manager: Stephanie Nava, M.A., senava@med.umich.edu


Mentorship of junior investigators, quarterly case conferences, developmental project funds, conference award funds for junior investigators.  Dementia for Scientists curriculum (https://alzheimers.med.umich.edu/for-professionals/)

Faculty Expertise

To download a PDF of this list, please click here.

Amanda Leggett, Ph.D.

Amanda Leggett, Ph.D.
Wayne State University
Assistant Professor, Institute of Gerontology and Department of Psychology
Michigan ADRC, Leaders Initiative, Clinical Core


Scientific expertise: Family caregiving for individuals living with dementia

Methods or instrumentation: Mixed-methods, qualitative and quantitative data analysis

Grant application reviews: Social and behavioral science applications surrounding dementia

Ana Daugherty, Ph.D.

Ana Daugherty, Ph.D.
Wayne State University
Assistant Professor, Institute of Gerontology, Department of Psychology, and Department of Psychiatry and Behavioral Neurosciences
Michigan ADRC, Leaders Initiative, Data Management and Statistical Core



Scientific expertise: Vascular and metabolic health factors that modify human brain aging and dementia risk. I use multimodal neuroimaging and blood biomarkers, actigraphy, neuropsychological assessment and health history to study longitudinal aging in community samples. Emphasis on pathways for hypertension-related risk for Alzheimer's disease and related dementia.

Methods or instrumentation: Multimodal MRI (structural T1, high-res hippocampal subfields, susceptibility weighted imaging, T2 FLAIR); actigraphy; (non-clinical) cognitive assessment

Training: Advanced statistics (multivariate methods, structural equation modeling, mixed models, reliability); MRI methods

Andrew Bender, Ph.D.

Andrew Bender, Ph.D.
Michigan State University
Assistant Professor, Department of Neurology and Ophthalmology
Michigan ADRC, Leaders Initiative, Neuroimaging Core


Scientific expertise: My expertise is in structural and diffusion MRI in the contexts of cognitive aging, lifespan development, and neurodegenerative disease. In addition to a host of methods for MRI processing, my work uses a variety of approaches for statistical analysis including structural equation modeling, mixed effects models, partial least squares, and path analysis.

Methods or instrumentation: MRI processing methods (e.g., ANTs, ASHS, FSL, Freesurfer, MRtrix, SPM); high dimensional analysis methods (e.g., clustering, mixed effects models); manual and automated brain segmentation methods; advanced diffusion MRI processing (e.g., MRtrix, NODDI, DKI)

Training: My lab has training resources for basic image processing, and we can offer consultation on image segmentation and diffusion MRI methods

Grant application reviews: Approach and significance of MRI methods, particularly for structural and diffusion MRI

Andrew Lieberman, M.D., Ph.D.

Andrew Lieberman, M.D., Ph.D.
University of Michigan
Gerald Abrams Collegiate Professor of Pathology
Michigan ADRC, Neuropathology Core Lead



Scientific expertise: Neuropathology, cellular and mouse models of neurodegeneration, polyglutamine and lysosomal disorders

Animal models: AR113Q; Npc1 -/-; Npc1 flox; human NPC1 I1061T

Methods or instrumentation: Molecular biology, biochemistry, histology

Training: Analysis of neuropathology

Grant application reviews: Mechanisms of neurodegeneration

Annalise Rahman-Filipiak, Ph.D.

Annalise Rahman-Filipiak, Ph.D.
University of Michigan
Assistant Professor, Department of Psychiatry
Michigan ADRC, Leaders Initiative, Clinical Core



Scientific expertise: Neuropsychology, cognitive aging, biomarker disclosure

Methods or instrumentation: Neuropsychological testing, PET imaging, feedback, biomarker disclosure, mixed methods

Training: Cognitive testing, test development and validation, psychometrics

Grant application reviews: Neuropsychology, cognitive aging, caregiving, TBI, Alzheimer's disease and related dementias

Benjamin Combs, Ph.D.

Benjamin Combs, Ph.D.
Michigan State University
Research Assistant Professor, Department of Translation Science and Molecular Medicine
Michigan ADRC, Leaders Initiative, Biomarker Core


Scientific expertise: I study the role of tau protein in neurodegenerative disease using protein biochemistry, cultured cells, and animal models. Specifically, I look at the role of tau protein in dysregulation of axonal transport as a potential mechanism of tau's toxicity in disease.

Animal models: TauKO: a mouse line with the MAPT gene knocked out. hTau: a mouse line with human MAPT gene replacing mouse tau.

Methods or instrumentation: Primary neuron culture, confocal microscopy, electron microscopy

Grant application reviews: Tau protein, axonal transport

Benjamin Hampstead, Ph.D., ABPP/CN

Benjamin Hampstead, Ph.D., ABPP/CN
University of Michigan
Stanley Berent, Ph.D., Collegiate Professor of Psychology
Michigan ADRC, Clinical Core Lead



Scientific expertise: I focus on the early detection of, and non-pharmacologic treatment for, cognitive deficits arising from neurologic injury and disease.

Core resources: UM-MAP data set

Methods or instrumentation: TMS, tES, fNIRS, s/fMRI, neuropsych measures, cognition-oriented treatments

Training: TMS, tES, fNIRS, s/fMRI, neuropsych measures, cognition-oriented treatments

Grant application reviews: Areas related to neuromodulation, neuroimaging, non-pharmacologic interventions, and diagnosis

Bruno Giordani, Ph.D.

Bruno Giordani, Ph.D.
University of Michigan
Professor of Psychology, Departments of Psychiatry, Neurology, Psychology
Chief Psychologist, Department of Psychiatry
Senior Director, Mary A. Rackham Institute
Michigan ADRC, Associate Director


Scientific expertise: Earliest appearance of cognitive and motor features in healthy aging and dementia. Nonpharmacological to cognitive loss in aging and medical illness.

Methods or instrumentation: Computer-based assessment, EEG methodologies

Training: Computer-based assessment and remediation of cognitive, motor, and behavioral features in medical illness and dementia

Grant application reviews: See previous

Other resources: Driving simulators

Dave Morgan, Ph.D.

Dave Morgan, Ph.D.
Michigan State University
Professor, Department of Translational Neuroscience
Michigan ADRC, Biomarker Core Co-Lead


Scientific expertise: Neurochemistry of memory. Mouse models of amyloidosis and tauopathy. Immunotherapy and gene therapy. CSF and Blood fluid biomarkers in AD

Animal models: APP+PS1 model of amyloidosis. PS19 model of tauopathy. Aged C57 mice.

Core resources: Access to SIMOA assays

Methods or instrumentation: Digital scanning microscopy, SIMOA protein measurement at fg/ml levels

Training: Quantitative microscopy

Grant application reviews: Animal models, drug development, fluid biomarkers

Courtney Polenick, Ph.D.

Courtney Polenick, Ph.D.
University of Michigan
Assistant Professor, Department of Psychiatry
Michigan ADRC, Leaders Initiative, Outreach, Recruitment and Engagement Core


Scientific expertise: Family relationships and caregiving, chronic illness management, and complex care needs including dementia and multimorbidity.

Methods or instrumentation: Daily diary and ecological momentary assessment, salivary biomarkers, dyadic data

Grant application reviews: Caregiving, chronic illness management, dyadic data

Doug Noll, Ph.D.

Doug Noll, Ph.D.
University of Michigan
Ann and Robert H. Lurie Professor of Biomedical Engineering
Professor, Department of Radiology
Co-Director, fMRI Center
Michigan ADRC, Neuroimaging Core Lead



Scientific expertise: Research is focused on the data acquisition and processing for imaging brain function using magnetic resonance imaging (functional MRI or fMRI). Projects include development of image acquisition and reconstruction techniques, post-processing and analysis methods, methods for elimination of movement and other artifacts, and the development of neuroimaging biomarkers for disease.

Core resources: Access to neuroimaging data for MADRC cohorts, consulting on design of imaging components and imaging biomarkers, consulting on image analysis

Methods or instrumentation: 3T MRI, Functional and Anatomical MRI

Training: MRI Physics, MRI protocols, fMRI experimental design

Grant application reviews: Imaging components

Henry Paulson, M.D., Ph.D.

Henry Paulson, M.D., Ph.D.
University of Michigan
Lucile Groff Professor of Neurology for Alzheimer’s Disease and Related Dementias
Interim Co-Director, Michigan Neuroscience Institute
Michigan ADRC, Director and Principal Investigator


Scientific expertise: Mechanisms of age-related neurodegenerative diseases

Animal models: multiple polyglutamien mouses models, esp. SCa3; P301S Tau tg ; A53T synuclein tg; WT-UBQLN2 and P506T-UBQLN2 tgtg

Methods or instrumentation: Basic molecular and cell biological methods

Training: Basic molecular and cell biological methods

Grant application reviews: Mechanisms of neurodegenerative diseases

Irving Vega, Ph.D.

Irving Vega, Ph.D.
Michigan State University
Associate Professor, Department of Translational Neuroscience
Michigan Center for Contextual Factors in Alzheimer’s Disease, Recruitment Core Co-Lead
Michigan ADRC, REC Co-Lead



Scientific expertise: Proteome changes associated with the accumulation of pathological tau. Identification of biomarkers in tissue and biofluids. Health disparities associated with ADRD.

Animal models: JNPL3 - expresses htauP301L under the prion promoter (SW background as developed at Mayo Clinic JAX by Mike Hutton and Jada Lewis))

Other resources: At the Integrated Mass Spectrometry Unit, we provide proteomics services. https://translationalscience.msu.edu/resources/proteomics.html

Methods or instrumentation: Mass spectrometry-based proteomics for the identification and quantification of proteins and PTMs

Training: Proteomics

Grant application reviews: Projects related to tauopathies that involves molecular and biochemical approaches. Also, projects that propose interventions related to ADRD in underserved and underrepresented groups.

Jeske Damoiseaux, Ph.D.

Jeske Damoiseaux, Ph.D.
Wayne State University
Associate Professor, Institute of Gerontology, Department of Psychology
Michigan ADRC, Leaders Initiative, Neuroimaging Core

damoiseaux@wayne.edu | connectlab.wayne.edu

Scientific expertise: Age and disease related changes in cognition and brain structure and function. Early detection of atypical brain changes and identifying risk groups. Possible interventions to delay cognitive decline.

Methods or instrumentation: Functional and structural MRI; brain network connectivity

Training: General MRI data analyses; specific functional connectivity analyses

Grant application reviews: Cognitive and brain changes in aging and neurodegenerative disease; specifically, neuroimaging applications

Joan Ilardo, PhD  

Joan Ilardo, Ph.D.
Michigan State University
College of Human Medicine, Director of Research Initiatives
Michigan Dementia Coalition
Michigan ADRC, Outreach, Recruitment and Engagement Core Investigator


Scientific expertise: Health Services Research and Implementation Science, Chronic Disease Self-Management Program Implementation and Evaluation

Training: Translational research phases T3 and T4

Grant application reviews: Translational research phases T3 and T4

Judith Heidebrink, M.D., M.S.

Judith Heidebrink, M.D., M.S.
University of Michigan
Richard D. and Katherine M. O’Connor Research Professor of Neurology
Michigan ADRC, Clinical Core Co-Lead


Scientific expertise: Clinical research pertinent to diagnosis/management of dementia, including clinical trials in the prevention and treatment of Alzheimer's disease

Methods or instrumentation: Clinical trial methodology

Training: Clinical trial methodology

Grant application reviews: Clinical trials in dementia prevention/treatment

Kelly Bakulski, Ph.D.

Kelly Bakulski, Ph.D.
University of Michigan
Assistant Professor, Department of Epidemiology, School of Public Health
Michigan ADRC, Data and Statistical Core Lead



Scientific expertise: Environmental chemical and genetic risk factors for neurological disorders using epidemiology and toxicology methods.

Core resources: Contact information for study recruitment, data for secondary analyses, database design/automation, statistical consultation for grant/manuscript, collaboration for analyses for grant/manuscript

Methods or instrumentation: Data preprocessing and analysis for genetics, RNA expression, epigenetics, and exposomics

Training: I teach three regular classes in programming in R statistical software, epigenomics data QC and analyses, and pathophysiology

Grant application reviews: Epidemiology, toxicology, genetics, environmental exposures

Luis Hernandez-Garcia, PhD

Luis Hernandez-Garcia, Ph.D.
University of Michigan
Research Professor, Department of Biomedical Engineering and Functional MRI Laboratory
Co-Director, Animal MRI Facility



Scientific expertise: MRI, brain blood flow, non-invasive neuromodulation

Methods or instrumentation: MRI

Training: MRI, signal processing, mathematical modeling

Grant application reviews: MRI, signal processing, mathematical modeling

Marcia Gordon, Ph.D. 

Marcia Gordon, Ph.D.
Michigan State University
Professor of Translational Neuroscience



Scientific expertise: I am especially interested in the role of innate immunity in aging and neurodegenerative disease.  Increasingly, my research focuses on developing novel therapeutics to modulate innate immunity, including small molecule agents, vaccines, gene therapy and biologics, using transgenic mouse models with Alzheimer-like pathology.

Animal models: APP+PS1 transgenic mice = age-dependent accumulation of amyloid deposits, cognitive deficits and innate immune activation; rTg4510 = transgenic mice overexpressing 4R tau, with age-dependent tau phosphorylation, aggregation and deposition leading to cognitive impairments; PS-19= similar to Tg4510 but less aggressive.

Methods or instrumentation: Bench-top cell sorter, mouse behavior facility, digital slide scanner and computer-assisted image analysis

Grant application reviews: Innate immune activation, mouse models, innate immunity, glial activation

Navid Seraji, M.D.

Navid Seraji, M.D.
University of Michigan
Associate Professor of Neurology


Scientific expertise: MRI measures of neuro degeneration and disease progression.

Methods or instrumentation: MRI, morphometrics, fMRI, MRS and diffusion MR

Training: Post processing of MR data

Grant application reviews: Imaging research

Nick Kanaan, Ph.D.

Nick Kanaan, Ph.D.
Michigan State University
Associate Professor of Translational Neuroscience
Michigan ADRC, Biomarker Core Co-Lead



Scientific expertise: Molecular mechanisms of disease with a focus on Alzheimer's disease and other tauopathies, as well as tau protein biology and pathobiology

Animal models: Wild-type C57 mice; PS19 transgenic mice: mice harboring P301S mutant tau; Human tau knockin mice (Saido model): endogenous mouse tau gene was replaced with human tau gene and mice express all 6 human tau isoforms; Tau knockout mice: endogenous mouse tau gene was removed

Core resources: Blood (or other biological fluid) biomarker assessments via SIMOA immunoassays and/or mass spectrometry

Methods or instrumentation: Microscopy (TEM, confocal), Recombinant protein, monoclonal antibody production, biomarkers (SIMOA immunoassays), histology, biochemical assays, molecular biology assays, cell culture (including primary neurons), rodent models of tauopathy

Training: Any of the previous

Grant application reviews: Grants on AD, tauopathy, tau, aging, PD

Peter Lichtenberg, Ph.D.

Peter Lichtenberg, Ph.D.
Wayne State University
Distinguished University Service Professor of Psychology
Director of the Institute of Gerontology and Merrill Palmer Skillman Institute
Michigan ADRC, REC Co-Lead



Scientific expertise: Clinical geropsychology and geriatric neuropsychology; Financial decision making and neurocognitive decline; intersection of declining cognition, financial management and financial exploitation.

Core resources: REC provides a number of opportunities including developmental funds

Methods or instrumentation: Interviews, cognitive assessment

Training: Community engaged research, financial capacity measurement; Engaging with African American communities to enhance research participation

Grant application reviews: Behavioral science grants--both basic and intervention; Community based work in behavioral sciences

Peter Tessier, Ph.D.

Peter Tessier, Ph.D.
University of Michigan
Albert M. Mattocks Professor of Pharmaceutical Sciences and Chemical Engineering



Scientific expertise: My lab focuses on therapeutic antibody discovery, engineering, and optimization of affinity and specificity. We also work on delivery of antibodies to the brain using bispecific antibodies.

Animal models: Wild type and PS19 (tau) mice

Methods or instrumentation: Mammalian protein production (suspension HEK 293 and CHO), immunization and in vitro antibody library generation, single B-cell sorting for antibody generation, flow cytometry and FACS

Training: Mammalian antibody production, antibody discovery and engineering

Grant application reviews: Therapeutic antibodies

Robert A. Koeppe, Ph.D.

Robert A. Koeppe, Ph.D.
University of Michigan
Professor of Radiology


Scientific expertise: Research interests center around the quantitative aspects of positron emission tomography (PET). Specific research areas include the development and implementation of tracer kinetic models for new and existing positron labeled radiotracers. Has extensive experience in multi-center trials involving PET imaging of amyloid and tau.

Methods or instrumentation: PET Scanning

Roger L. Albin, M.D.

Roger L. Albin, M.D.
University of Michigan
Anne B. Young Collegiate Professor, Department of Neurology
Michigan ADRC, Research Education Component Lead


Scientific expertise: Movement Disorders; Neurodegeneration Clinical Research

Methods or instrumentation: PET Scanning

Training: Participant characterization

Grant application reviews: Neurodegeneration research

Sami Barmada, Ph.D.

Sami Barmada, Ph.D.
University of Michigan
Angela Dobson Welch and Lyndon Welch Research Professor of Neurology
Director, Michigan Brain Bank
Michigan ADRC, Leaders Initiative, Neuropathology Core



Scientific expertise: We focus on disease mechanisms and therapeutic strategies in amyotrophic lateral sclerosis and frontotemporal dementia. Our objective is to use these models to test and identify effective new therapeutics; and define the pathways culminating in neurodegeneration in these disorders.

Animal models: primary neurons isolated from rodents (rattus norvegicus, mus musculus) or human stem cell derived neurons from individuals with sporadic and familial disease

Lab resources: We are happy helping with imaging needs and disease modeling.

Other resources: Longitudinal microscopy, super-resolution microscopy

Methods or instrumentation: High content microscopy, super-resolution microscopy, longitudinal microscopy, directed differentiation of stem cells into neuronal subtypes

Training: Fluorescence microscopy, super-resolution microscopy, human neuron differentiation from stem cells

Grant application reviews: Basic science of FTD/ALS, protein and RNA homeostasis, disease modeling

Sarah Elzinga, Ph.D.

Sarah Elzinga, Ph.D.
University of Michigan
Edith Briskin Emerging Scholar
Postdoctoral Fellow, NeuroNetwork for Emerging Therapies



Scientific expertise: Immuno-metabolic interactions in the CNS

Animal models: C57BL6 high fat diet induced obesity and prediabetes

Methods or instrumentation: IHC (floating sections and confocal microscopy), Western blotting, Cognitive testing in mice

Training: IHC (floating sections and confocal microscopy), Western blotting, Cognitive testing in mice

Grant application reviews: Basic review of scientific content and minor editing of language/structure

Scott Counts, Ph.D.

Scott Counts, Ph.D.
Michigan State University
Associate Professor of Translational Neuroscience



Scientific expertise: Cellular and molecular mechanisms of AD and VCID

Animal models: 3 rat models: Tg344-19 AD (F344 rats carrying APPswe and PS1d9); Spontaneously hypertensive stroke-prone rats (SHRSPs, Wistar-Kyoto rats with naturally occuring vascular abnormalities); "Frankenrats" (Tg344-19 AD rats backcrossed onto SHRSPs as a model for VCID)

Methods or instrumentation: Laser capture microdissection (LCM)

Training: LCM; single neuron gene expression analysis; rat behavioral training; stereotactic surgery; all standard molecular, cell biological, histological, and biochemical assays

Grant application reviews: Anything dementia related but specifically anything that would be handled by CNN study section

Scott Peltier, Ph.D.

Scott Peltier, Ph.D.
University of Michigan
Technical Director and Research Scientist Functional MRI Laboratory



Scientific expertise: MRI acquisition and data analysis

Core resources: The lab offers pilot grants for investigators to allow collection of preliminary data

Methods or instrumentation: Human MRI scanners (3T)

Training: Our lab runs a yearly FMRI course

Grant application reviews: Imaging applications

Scott Roberts, Ph.D.

Scott Roberts, Ph.D.
University of Michigan
Professor, Health Behavior and Health Education
Michigan ADRC, Outreach, Recruitment and Engagement Core Lead



Scientific expertise: Health communication; bioethics; dementia education; health psychology, especially as applied to genetic testing

Core resources: We can help assist studies actively trying to recruit participants; we can offer speaking opportunities / feature articles on our website/newsletter to promote visibility of their work

Methods or instrumentation: Social and behavioral health surveys

Training: Social / behavioral interventions / surveys; RCR / ELSI

Grant application reviews: Grants addressing psychosocial issues posed by Alzheimer's disease

Sean Ferris, M.D., Ph.D.   

Sean Ferris, M.D., Ph.D.
University of Michigan
Assistant Professor, Neuropathology in the Department of Pathology
Michigan ADRC, Leaders Initiative, Neuropathology Core

Scientific expertise: Clinical neuropathology (surgical, muscle/nerve, dementia brain autopsy diagnosis), PhD in biochemistry/glycoprotein folding, experience in mouse work

Methods or instrumentation: Whole slide scanning, immunohistochemistry through the U-M pathology department

Training: Neuropathology, mouse necropsy

Grant application reviews: Neuropathology, mouse necropsy

Sheria Robinson-Lane, PhD, RN  

Sheria Robinson-Lane, Ph.D., R.N.
University of Michigan
Assistant Professor, Department of Systems, Populations and Leadership, School of Nursing
Michigan ADRC, Leaders Initiative, Outreach Recruitment and Engagement Core



Scientific expertise: My work examines the personal, familial, and structural adaptations necessary for diverse older adults to age in place with cognitive and/ or physical disabilities. This work is evaluated through a health equity lens.

Methods or instrumentation: Content analysis, ethnography, mixed-methods study design

Grant application reviews: Pain and symptom management, informal caregiving, long term care services, community based participatory research, anti-racism